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Clinical Chemistry

Image: The three-dimensional (3D) herringbone nanopatterned microfluidic chip that detects cancer faster (Photo courtesy of the University of Kansas).

Nanopatterned Microfluidic Chip Detects Cancer Markers

The performance of current microfluidic methods for exosome detection is constrained by boundary conditions, as well as fundamental limits to microscale mass transfer and interfacial exosome binding. More...
13 Mar 2019
Image: The pHOx Ultra blood gas analyzer is used for routine blood gas analysis (Photo courtesy of Nova Biomedical).

Analysis Compared for Accurate Pleural Fluid pH Determination

Pleural effusion is the pathological accumulation of pleural fluid resulting from excess fluid production and/or increased transpleural pressure, increased capillary permeability, and impaired lymphatic drainage. More...
12 Mar 2019
DIASOURCE (A Biovendor Company)
Image: Blood samples are loaded into a mass spectrometer to analyze them for signs of metabolic variations that could signal autism spectrum disorder (Photo courtesy of NeuroPointDX).

Blood Test Identifies Amino Acid Metabotypes Associated with Autism

Autism spectrum disorder (ASD) could benefit from new and improved diagnostic methods and the arrival of a newly commercialized blood test, along with other efforts headed toward a similar end goal, and could be nudging the field toward earlier detection and intervention. More...
06 Mar 2019
Image: The API 4000 liquid-chromatography mass spectrometry system (Photo courtesy of SCIEX).

Vitamin D Measured in Human Hair

Vitamin D deficiency has reached epidemic proportions worldwide, with over one billion people estimated to be affected. Deficiency has been linked with bone health, but it could also be a risk factor for depression, cardiovascular disease, inflammation, diabetes and cancer. More...
05 Mar 2019
Image: The 3100 OFFGEL Fractionator (Photo courtesy of Agilent Technologies).

Blood Test Detects Alzheimer's Disease before Symptoms Appear

A blood-based assessment of preclinical disease would have huge potential in the enrichment of participants for Alzheimer’s disease (AD) therapeutic trials. More...
27 Feb 2019
Image: Procalcitonin (PCT) levels and their relation to the clinical sepsis and septic shock (Photo courtesy of Technology Networks).

Procalcitonin Evaluated as Sepsis Diagnostic Marker

Sepsis is a potentially life-threatening condition caused by the body's response to an infection and occurs when the body's response to chemicals released into the bloodstream is out of balance, triggering changes that can damage multiple organ systems. More...
27 Feb 2019
Image: The bile acid blood test is used to predict stillbirth risk (Photo courtesy of bluehorizon).

Simple Bile Acid Blood Test Predicts Stillbirth Risk

Intrahepatic cholestasis of pregnancy (ICP) is caused by a build-up of bile acids in the blood, and symptoms include pruritus. ICP is a liver disorder affecting approximately 5,300 pregnancies annually in the UK, more than 14 every day. More...
25 Feb 2019
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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