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Pathology

Image: Microscopic examination of bronchoalveolar lavage fluid revealing the presence of Strongyloides stercoralis larvae in hemorrhagic background (Photo courtesy Kyung-Nyeo Jeon, MD, PhD).

Severe Strongyloidiasis Infection Reported in Kidney Transplant Recipients

 Strongyloides stercoralis is a soil-transmitted human pathogenic parasitic roundworm causing the disease strongyloidiasis. It is found in tropical and subtropical regions worldwide. Many people infected are asymptomatic at first. Symptoms include dermatitis: swelling, itching, larva currens, and mild hemorrhage at the site where the skin has been penetrated. More...
25 Feb 2020
Image: Proteogenomic Characterization of Endometrial Carcinoma (Photo courtesy of the Clinical Proteomic Tumor Analysis Consortium).

Proteogenomic Characterization of Endometrial Carcinoma Analyzed

 Endometrial cancer is a cancer that arises from the endometrium which is the lining of the uterus or womb. It is the result of the abnormal growth of cells that have the ability to invade or spread to other parts of the body. More...
24 Feb 2020
DIASOURCE (A Biovendor Company)
Image: This side-by-side comparison of a breast tissue biopsy demonstrates some of the infrared-optical hybrid microscope’s capabilities. On the left, a tissue sample dyed by traditional methods. Center, a computed stain created from infrared-optical hybrid imaging. Right, tissue types identified with infrared data. The pink in this image signifies malignant cancer (Photo courtesy of Rohit Bhargava, PhD).

All-Digital Histopathology Attained by Infrared-Optical Hybrid Microscopy

 The gold standard of tissue pathology is to add dyes or stains so that pathologists can see the shapes and patterns of the cells under a microscope. However, it can be difficult to distinguish cancer from healthy tissue or to pinpoint the boundaries of a tumor, and in many cases diagnosis is subjective. More...
24 Feb 2020
Image: Normal electrocardiogram (ECG) and an ECG showing QT interval prolongation (long QT syndrome). The P wave represents atrial depolarization; the QRS complex, ventricular depolarization; and the T wave, ventricular repolarization. The QT interval is measured from the beginning of the QRS complex to the return of the T wave to the isoelectric line (Photo courtesy of Mayo Clinic).

Several Genes Linked to Long QT Syndrome Reappraised

 Long QT syndrome (LQTS) is the first described and most common inherited arrhythmia. Over the last 25 years, multiple genes have been reported to cause this condition and are routinely tested in patients. More...
20 Feb 2020
Image: Histopathology of Lung adenocarcinoma (Photo courtesy of Nikon).

Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans

 Lung adenocarcinoma is a subtype of non-small cell lung cancer (NSCLC). Lung adenocarcinoma is categorized as such by how the cancer cells look under a microscope. Lung adenocarcinoma starts in glandular cells, which secrete substances such as mucus, and tends to develop in smaller airways, such as alveoli. More...
18 Feb 2020
Image: Histopathology of early gastric cancer, an intramucosal adenocarcinoma. A blood test used in a targeted methylation (TM) sequencing assay may help detect hard-to-detect gastrointestinal cancers in asymptomatic individuals (Photo courtesy of Andrey Bychkov, MD, PhD).

Blood Test Lead to Earlier Detection of Gastrointestinal Cancers

 Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract (GI tract) and accessory organs of digestion, including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus. More...
13 Feb 2020
Image: Workflow of cancer personalized profiling by deep sequencing (CAPP-Seq) circulating tumor-DNA analysis (ctDNA) (Photo courtesy of Rashedul Islam Rony, PhD).

Lung Cancer Liquid Biopsy Guides MRD-Directed Adjuvant Therapy

 Minimal residual disease (MRD) is the name given to small numbers of leukemic cells (cancer cells from the bone marrow) that remain in the person during treatment or after treatment when the patient is in remission or have no symptoms or signs of disease. More...
11 Feb 2020
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.

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