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Immunology

Image: Schematic diagram of Type 1 Diabetes (TID). Immune Response to Insulin Could Identify and Help Treat Those at Risk for TID (Photo courtesy of Harvard Medical school).

Immune Response to Insulin Identifies Risk of Juvenile-Diabetes

Type 1 diabetes (T1D), also known as juvenile diabetes, is a form of diabetes in which very little or no insulin is produced by the islets of Langerhans (containing β-cells) in the pancreas. Insulin is a hormone required for the body to use blood sugar. More...
08 Mar 2021
Image: The Atellica CH 930 Immunoassay & Clinical Chemistry Analyzer (Photo courtesy of Siemens Healthcare).

Fibrinogen to Albumin Ratio Reflects ANCA‐Associated Vasculitis Activity

Microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) belong to a group of anti-neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV). More...
04 Mar 2021
Image: Schematic diagram of Rh alloimmunization in chronically transfused patients with thalassemia receiving RhD, C, E, and K matched transfusions (Photo courtesy of The Children’s Hospital of Philadelphia).

Rh Alloimmunization Explored in Chronically Transfused Thalassemia Patients

Chronic life-long transfusions are often required for patients with severe thalassemia to provide normal red blood cells and to suppress the patients’ own ineffective erythropoiesis. Cumulative exposure increases the risk for red cell alloimmunization and subsequent delayed hemolytic transfusion reactions (DHTRs). More...
01 Mar 2021
Image: The Simoa HD-1 Analyzer is a novel fully automated digital immunoassay analyzer with single-molecule sensitivity and multiplexing (Photo courtesy of Quanterix).

Blood Biomarker Predicts Dementia in Cerebral Small Vessel Disease

Cerebral small vessel disease (SVD) is a highly prevalent condition, which causes lacunar stroke, vascular cognitive impairment and vascular dementia. Few treatments have been shown to delay disease progression. More...
24 Feb 2021
Image: The BinaxNOW Legionella Urinary Antigen Card. Accurate. Rapid identification of Legionnaires` disease caused by Legionella pneumophila serogroup 1 with an easy-to-use technology (Photo courtesy of Abbott).

Urinary Antigen Test Kit Evaluated for Diagnosing Legionella Pneumonia

Legionellosis is caused by bacteria called Legionella. The disease has two different forms. Legionnaires’ disease is the more severe form of infection that causes pneumonia. Pontiac fever is caused by the same bacteria, but is a milder illness without pneumonia. More...
24 Feb 2021
Image: Glioblastoma omics highlights informative tumor features, immune subtypes (Photo courtesy of Washington University in St. Louis).

Proteogenomic And Metabolomic Studies Characterize Human Glioblastoma

Glioblastoma (GBM) is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells. Glioblastoma can occur at any age, but tends to occur more often in older adults. It can cause worsening headaches, nausea, vomiting and seizures. More...
23 Feb 2021
Image: T cell response in patients recovered from COVID-19 has been profiled using ImmunoScape TargetScape assay (Photo courtesy of The Scientist).

T Cell Response Profiled in COVID-19 Patients

The clinical spectrum of SARS-CoV-2 infection is highly variable, spanning from asymptomatic or subclinical infection, to severe or fatal disease. Characterization of the immune response to SARS-CoV-2 is urgently needed in order to better inform more effective treatment strategies, including antivirals and rationally designed vaccines. More...
22 Feb 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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