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Hematology

Image: Bone marrow aspirate from a patient with diffuse large B cell lymphoma (Photo courtesy of Peter Maslak).

Blood Test Predicts Lymphoma Therapy Success

A blood test can predict which patients with a type of cancer called diffuse large B cell lymphoma are likely to respond positively to initial therapy and which are likely to need more aggressive treatment. More...
04 Sep 2018
Image: Multiple myeloma, a cancer of the blood plasma (Photo courtesy of Medical News Today).

Multi-Omics Approach Guides Relapsed Multiple Myeloma Treatment

Many patients with relapsed multiple myeloma are not often matched with correct treatment options in a timely or personalized manner, and most patients have a median survival rate of six years. With standard diagnosis and treatment, relapses are usually inevitable and fatal for most patients. More...
30 Aug 2018
Image: The STA COMPACT MAX 2 is a fully automated benchtop analyzer (Photo courtesy of Diagnostica Stago).

Coagulation Tests Affected by Sodium Citrate Concentration

Despite a high degree of standardization, coagulation tests largely depend on preanalytic factors. Apart from artifacts acquired during blood drawing and transportation, the in vitro anticoagulant used has a potential impact on the coagulation test result. More...
27 Aug 2018
Image: The HaloPlex system enables fast, simple and efficient analysis of genomic regions of interest in a large number of samples (Photo courtesy of Agilent Technologies).

Mutations Identified As Cause for Rare Bone Marrow Disorder

Scientists have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder. The answer may allow some children to avoid the risk and expense of bone marrow transplantation, a common treatment for leukemia and bone marrow disorders. More...
09 Aug 2018
Image: The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies (Photo courtesy of PerkinElmer).

Homogeneous BTK Occupancy Assay Developed

Bruton’s tyrosine kinase (BTK), a member of the tyrosine kinase expressed in the hepatocellular carcinoma (TEC) family of cytoplasmic protein tyrosine kinases, was initially identified as the pathogenic protein in X-linked agammaglobulinemia, a human primary immune deficiency disease. More...
02 Aug 2018
Image: A blood smear from a patient with acute myeloid leukemia showing very large, immature myeloblasts with many nucleoli. A distinctive feature of these blasts is a linear red \"Auer rod\" composed of crystallized granules (Photo courtesy of University of Utah Medical School).

Acute Myeloid Leukemia Risk Predicted in Healthy Individuals

The incidence of acute myeloid leukemia (AML) increases with age and mortality exceeds 90% when diagnosed after age 65. Most cases arise without any detectable early symptoms and patients usually present with the acute complications of bone marrow failure. More...
25 Jul 2018
Image: A blood smear shows size heterogeneity of peripheral red blood cells, known as anisocytosis (Photo courtesy of Dr. Jay Park, MD).

Hematological Parameters Predict Severity of Acute Pancreatitis

Acute pancreatitis (AP) is an acute inflammation of the pancreatic parenchyma induced by activated pancreatic enzymes due to multiple causes. Current severity scores include multiple variables and some of them are only complete within 48 hours of admission. More...
23 Jul 2018
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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