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Clinical Chemistry

Image: The SEQPRO LIPO IS assay is for the genetic diagnosis of familial hypercholesterolemia (Photo courtesy of Progenika Biopharma).

Genetic Familial Hypercholesterolemia Prevalent in Premature CVD

Premature coronary artery disease (CAD) is a major cause of mortality and morbidity. Increased low-density lipoprotein-cholesterol (LDL-C) level is a major risk factor for CAD and thus the main target for its prevention. More...
12 Jun 2019
Image: The KRYPTOR compact PLUS fully automated random access immunoassay analyzer (Photo courtesy of BRAHMS).

Plasma Copeptin Reveals Presence and Severity of Liver Disease

Vasopressin (VP) is a hormone secreted by the pituitary gland in response to increased plasma osmolality, low plasma volume, and low blood pressure. Copeptin is a cleavage product of the C-terminal part of the VP precursor which correlates well with plasma VP concentrations and which is easier to measure reliably. More...
11 Jun 2019
Image: A molecule model of Apo E (Photo courtesy of Wikimedia Commons).

Study Confirms Association of AD and High Levels of LDL Cholesterol

High LDL cholesterol levels have been linked to the risk of developing early-onset Alzheimer's disease (AD). More...
10 Jun 2019
Image: A diagram of the 3D-printed microchip electrophoresis device that can sensitively detect three serum biomarkers of preterm birth (Photo courtesy of Brigham Young University).

3D-Printed Device Detects Biomarkers of Preterm Birth

Preterm birth (PTB), defined as birth before the 37th week of gestation, is the leading complication of pregnancy and it affects about 1 in 10 pregnancies worldwide. Preterm infants can suffer complications such as neurological, respiratory and cardiac problems and, in some cases, even death. More...
06 Jun 2019
Image: Tendinous xanthomas on the hand of a patient with familial hypercholesterolemia (Photo courtesy of ScreenPro FH).

Blood Donations Screened for Familial Hypercholesterolemia

Familial hypercholesterolemia is an autosomal-dominant disorder that often causes premature coronary artery disease. Unfortunately, familial hypercholesterolemia remains largely undiagnosed. More...
06 Jun 2019
Image: The Combur-10 brand of reagent strips for urinalysis can be used for cerebrospinal fluid analysis (Photo courtesy of Roche Diagnostics).

Reagent Strips Test Analyzed for CSF in Neurological Disorders

Cerebrospinal fluid (CSF) examination is often performed in emergency to obtain diagnostic information of various life threatening conditions such as meningitis, subarachnoid hemorrhage, demyelinating diseases or carcinomas. More...
05 Jun 2019
Image: Serum Cyr61 concentrations and diagnostic performance of Cyr61 in participants in the training cohort. A: Levels of serum Cyr61 in healthy controls and RA patients (Photo courtesy of Peking University First Hospital).

Cysteine-Rich 61 Biomarker Reflects RA Disease Activity

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes progressive articular damage, functional loss, and comorbidity. Until now, the exact pathological processes involved in RA remain incompletely understood. More...
05 Jun 2019
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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