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Clinical Chemistry

Image: Simoa is an ultra-sensitive immunoassay technology that allow detection of proteins and nucleic acids at lowest possible levels (Photo courtesy of Quanterix)

Plasma Amyloid-β 42/40 Assays Compared in Alzheimer Disease

Blood-based tests for brain amyloid-β (Aβ) pathology are needed for widespread implementation of Alzheimer disease (AD) biomarkers in clinical care and to facilitate patient screening and monitoring of treatment responses in clinical trials. More...
14 Oct 2021
Image: The SCIEX QTRAP 6500+ system combines triple quadrupole mass spectrometry with linear ion trap (LIT) (Photo courtesy of Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences)

Folate, Vitamin B12 Tied to GDM Risk in Early Pregnancy

Gestational diabetes mellitus (GDM) is a common medical disorder in pregnancy, estimated to affect more than 20 million pregnancies worldwide, and causes significant short- and long-term consequences to both the women and their offspring. More...
12 Oct 2021
Image: Laboratory water systems from Carolina Liquid Chemistries (Photo courtesy of Carolina Liquid Chemistries, Corp.)

Carolina Liquid Chemistries Corp. Introduces Line of Water Systems for Clinical Chemistry Analyzers

Carolina Liquid Chemistries, Corp. (CLC, Greensboro, NC, USA) has introduced a new line of laboratory water systems to the US market. The water system is offered in two models for compatibility with a variety of automated clinical analyzers. More...
07 Oct 2021
Image: The AU5800 Clinical Chemistry Analyzer is an automated chemistry analyzer that measures many different chemical analytes (Photo courtesy of Beckman Coulter)

Differential Biochemical Markers Identified in Inflammatory Processed Synovial Fluid

Joint infections with a non-specific presentation are difficult to diagnose, mainly due to the absence of specific clinical signs and symptoms, relative lack of accurate laboratory tests, low virulence due to previous treatment, and biofilm ability of the pathogens. More...
06 Oct 2021
Image: DxU Iris Workcell Urinalysis Solution (Photo courtesy of Beckman Coulter, Inc.)

New Urinalysis Solution Improves Laboratory Workflow by Reducing Manual Reviews and Sample Processing Time

Beckman Coulter, Inc. (Brea, CA, USA) has launched the DxU Iris Workcell, its new fully automated system that streamlines urinalysis workflow and reduces manual reviews to 4%. More...
05 Oct 2021
Image: Higher blood high density lipoprotein and apolipoprotein A1 levels are associated with reduced risk of developing amyotrophic lateral sclerosis (Photo courtesy of Forth)

Blood Lipid Biomarkers Associated with Lower Risk of ALS

Amyotrophic lateral sclerosis (ALS) ALS belongs to a wider group of disorders known as motor neuron diseases, which are caused by gradual deterioration (degeneration) and death of motor neurons. Motor neurons are nerve cells that extend from the brain to the spinal cord and to muscles throughout the body. More...
30 Sep 2021
Image: The Ketonix Breath Ketone Analyzer may be considered as a non-invasive screening tool to rule out ketosis in adults with type 1 diabetes (Photo courtesy of Ketonix)

Breath Ketone Analyzer Accurately Detects Ketosis in Type 1 Diabetes

The presence of high levels of ketones in the bloodstream is a common complication of diabetes, which if left untreated can lead to ketoacidosis. Ketones build up when there is insufficient insulin to help fuel the body’s cells. More...
30 Sep 2021
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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