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Clinical Chemistry

Image: The UriSed 3 PRO is a professional automated urine sediment analyzer with a revolutionary new optical system combining bright-field and phase contrast microscopy (Photo courtesy of 77 Elektronika)

Automated Urine Microscope Verified for Regional Laboratories

Automated Urine Microscopy examines a sample of urine under a microscope. It can check cells from the urinary tract, blood cells, crystals, bacteria, parasites, and cells from tumors. This test is often used to confirm the findings of other tests or add information to a diagnosis. More...
03 Feb 2021
Image: ACQUITY I-Class UPLC coupled with Xevo TQ-S mass spectrometer (Photo courtesy of Waters Corporation).

UPLC-MS/MS Method Simultaneously Determines Plasma Catecholamines and Their Metabolites

Phaeochromocytomas and paragangliomas (PPGLs) are rare tumors of adrenal chromaffin cells or extra-adrenal paraganglia. They are difficult to diagnose because of the non-specific clinical symptoms such as hypertension, palpitations, flushing and sweating. More...
27 Jan 2021
DIASOURCE (A Biovendor Company)
Image: Tryptophan metabolism is dysregulated in individuals with Fanconi anemia (Photo courtesy of Cincinnati Children’s Hospital Medical Center).

Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia

Fanconi anemia (FA) is a complex genetic disorder frequently associated with progressive marrow failure and a strong predisposition to early malignancies, particularly squamous cell carcinomas and hepatocellular carcinomas. More...
20 Jan 2021
Image: Photomicrograph of a section of human skin showing a vacuolar interface dermatitis with dermal mucin. These findings are consistent with discoid skin lesions in lupus dermatitis (Photo courtesy of Nephron).

Serum Pentosidine Levels Measured in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. More...
14 Jan 2021
Image: Human Total Angiopoietin ELISA assay (Photo courtesy of Immuno-biological laboratories Co).

Angiopoietin-Like 2 Is a Biomarker for Diabetic Foot Patients

Diabetic foot ulcers (DFUs) are one of the common complications in type 2 diabetes mellitus patients and are chartered by lower extremity vascular obstructions, persistent foot infections, ulcers, and deep tissue destruction. More...
14 Jan 2021
Image: The VITALAB Selectra ProS Biochemical Analyzer System (Photo courtesy of ELITechGroup).

Gestational Lipid Profiles Associated with Adverse Cardiovascular Risk

Pregnancy has been proposed as a natural ‘stress test’ to predict the risk of cardiovascular disease (CVD) later in life. The long-term effect of high blood pressure during pregnancy has been well established. Women who develop a hypertensive disorder of pregnancy such as gestational hypertension or pre-eclampsia have a 2–8 times higher risk of developing chronic hypertension and other diseases. More...
12 Jan 2021
Image: Preliminary Predictive Criteria Identified For COVID-19 Cytokine Storm (Photo courtesy of University of L’Aquila).

Preliminary Predictive Criteria Identified for COVID-19 Cytokine Storm

While most of cases of COVID-19 are mild, a sizeable number of patients develop a severe acute hyperimmune response characterized by a cytokine storm (CS). Two forms of CS, hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS), rely on well-established criteria to identify their occurrence. More...
05 Jan 2021
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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