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BioResearch

Image: A micrograph showing a lymph node invaded by ductal breast carcinoma, with an extension of the tumor beyond the lymph node (Photo courtesy of Wikimedia Commons).

Elevated Collagen XIII Levels Linked to Breast Cancer Metastasis

Elevated levels of the transmembrane protein collagen XIII were found to be associated with breast cancer metastasis, cell invasion, anoikis resistance, and poor prognosis for the patient. More...
23 Oct 2018
Image: Researchers have found a deficiency in the protein STIM1 in brain tissue from patients with Alzheimer\'s disease. Its involvement in neurodegenerative processes has been verified by CRISPR/Cas9 gene editing (Photo courtesy of the University of Extremadura).

Gene Editing Used to Mimic Dysfunctional Neurodegenerative Calcium Transport

A team of neurodegenerative disease researchers working with various Alzheimer's disease model systems has found that expression levels of the STIM1 gene in brain tissues decreased with the progression of neurodegeneration. More...
22 Oct 2018
Image: Cells that are normally bright green turn bright red after lipid nanoparticles have delivered an mRNA cargo encoding Cre protein. Cells that are red contain the mRNA, while green cells do not (Photo courtesy of Daryll Vanover, Georgia Institute of Technology).

Screening Technique Finds Endothelial Cells Targeted by Nanoparticles

A recently developed technique allows researchers to identify lipid nanoparticles that preferentially target endothelial cells – rather than liver cells – for transport of the components of the CRISPR/Cas9 gene-editing tool. More...
18 Oct 2018
Image: A photomicrograph of small cell neuroendocrine prostate cancer: cancer cells are seen expressing diagnostic prostate cancer markers in green and red (blue color indicates the cell nucleus) (Photo courtesy of Jung Wook Park & Owen Witte, University of California, Los Angeles).

Research Determines Why Different Cancers Display Similar Profiles

A team of cancer researchers has identified a molecular mechanism that may explain why gene expression profiles are similar in late stage cancers from different organs. More...
17 Oct 2018
Image: A diagram of a fundamentally new molecule that can halt proliferation and growth of breast cancer cells in the laboratory (Photo courtesy of the Stevens Institute of Technology).

Molecular Scaffolds Promise Drug Synthesis in Breast Cancer Treatment

A recently developed class of molecular scaffolds for treatment of breast cancer promises to facilitate the synthesis of drugs capable of degrading or inhibiting estrogen receptors (ERs). More...
16 Oct 2018
Image: A three-dimensional (3D) representation of the chemical structure of trans-resveratrol (Photo courtesy of Wikimedia Commons).

Targeted Delivery of Resveratrol Prevents Lung Cancer in Model

A team of Swiss cancer researchers prevented development of lung cancer in a mouse model system using a method, which they had developed, that delivered high concentration dosages of the natural cancer chemoprevention compound resveratrol directly to the animals' lungs. More...
15 Oct 2018
Image: A digitally colorized transmission electron microscopic (TEM) image of Zika virus. Virus particles, here colored blue, are 40 nanometers in diameter, with an outer envelope and an inner dense core (Photo courtesy of the CDC).

Genetically Engineered Zika Virus Slows Tumor Growth in Model

Injecting mice carrying human glioblastoma tumors with modified Zika virus was shown to significantly reduce intracerebral tumor growth and prolong animal survival. More...
11 Oct 2018
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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