We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




Portable Quadruplex PCR System Unveiled

By LabMedica International staff writers
Posted on 08 Mar 2018
An early-access program for a portable real time quantitative polymerase chain reaction (qPCR) system has been launched. More...
The platform weighs one kilogram and can run quadruplex qPCR on each of four samples simultaneously.

The system combines low-light complementary metal–oxide–semiconductor, or CMOS, biosensors with microfluidics to miniaturize medical devices at a reduced cost. The system is initially targeting the platform toward the research and applied markets, and eventually diagnostics.

The system is called Maverick (Anitoa Systems, Menlo Park, CA) and is an ultra-portable, Bluetooth(R) 2.0 enabled qPCR system that is compatible with standard qPCR assays, with up to 4-channel multiplexing. Target applications are rapid, on-the-site nucleic acid test of infectious diseases; blood screening; food safety and environmental monitoring. Maverick features a 4-channel fluorescence optical system based on Anitoa ULS24 Ultra-low light Bio-imaging chip. With no internal moving parts, Maverick is rugged and requires no calibration to operate.

In terms of the thermal cycler itself, the instrument uses standard Peltier cycling, but Anitoa has adapted techniques from the computing industry to miniaturize its systems. For example, it used technologies to manage heat that are commonly used in handset manufacturing, and heat sink innovations from the personal computing industry. Overall, the system can heat at 5° C per second and cool at 4° C per second, enabling a sub-30-minute test cycle. The Maverick is different from some of the other available systems in that it is real-time PCR, so it is quantitative, and it can be multiplexed with optical channels enabling detection of up to four targets per tube. The company plans for a commercial release of the Maverick in the summer, and is currently supplying beta products as part of its early-access program.

Zhimin Ding, PhD, the CEO of Anitoa Systems, said, “Our system is a direct imaging system, so there is no need for calibration in the field. Subsequent image analysis software quantifies the reaction. In contrast, in systems that use a photodiode to pick up signal, alignment of the diode and tubes needs to be accurate, and re-calibrated if the machine is jolted or shaken. Compared to other systems, the Maverick is lighter and more portable, and, since Anitoa controls the manufacture of its optical components, it can be more cost competitive than a number of other systems. It will cost between USD 3,500 and USD 6,000, depending on the number of optical channels a customer needs in the instrument.” The device was shown at the Molecular Medicine Tri-Conference held February 11-16, 2018, in San Francisco, CA, USA.


New
Gold Member
Serological Pipets
INTEGRA Serological Pipets
Serological Pipet Controller
PIPETBOY GENIUS
New
Celiac Disease Test
Anti-Gliadin IgG ELISA
New
Staining Management Software
DakoLink
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








DIASOURCE (A Biovendor Company)

Channels

Molecular Diagnostics

view channel
Image: The RNA-seq based diagnostic test for pediatric leukemia ensures better outcomes for children with this common cancer (Photo courtesy of Qlucore)

RNA-Seq Based Diagnostic Test Enhances Diagnostic Accuracy of Pediatric Leukemia

A new unique test is set to reshape the way Acute Lymphoblastic Leukemia (BCP-ALL) samples can be analyzed. Qlucore (Lund, Sweden) has launched the first CE-marked RNA-seq based diagnostic test for pediatric... Read more

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: A simple blood test could replace surgical biopsies for early detecion of heart transplant rejection (Photo courtesy of Shutterstock)

Blood Test Detects Organ Rejection in Heart Transplant Patients

Following a heart transplant, patients are required to undergo surgical biopsies so that physicians can assess the possibility of organ rejection. Rejection happens when the recipient’s immune system identifies... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.