Specific Blood Test Diagnoses Early Onset Kidney Failure

Its utility as an accurate diagnostic marker of diabetic nephropathy, immunoglobulin A (IgA) nephropathy, other types of chronic kidney disease (CKD) and early onset kidney damage is well documented.

In the past, serum creatinine has been used as test for kidney function but this is subject to influence from diet, muscle mass, and exercise. In contrast, cystatin C is not affected by these factors and rises in concentration within blood in line with even minor decreases in kidney function. This allows it to be used for the diagnosis of early onset kidney failure which serum creatinine cannot detect.

The SPOTCHEM Banalyst CysC (Cystatin C) from ARKRAY Inc. (Kyoto, Japan) is an in vitro diagnostic product for the testing of kidney failure. It is used together with whole blood or plasma samples on the SPOTCHEM Banalyst SI-3610, which is being sold through ARKRAY Inc. The SPOTCHEM Banalyst SI-3610 uses Micro Total Analysis Systems (µ-TAS) technology to offer high precision measurement in a compact test system. The µ-TAS analysis system uses a microprocessed chip to include flow channels and reactions which then allows separation of blood cells, reagent mixing and other processes in a short space of time. CysC is the fourth reagent in the series joining glycosylated hemoglobin (HbA1c), C-reactive protein (CRP) and other diabetes and infectious diseases biomarkers.

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