We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Advertise with Us

Latest Issue

Clinical ChemistryMolecular DiagnosticsHematologyImmunologyMicrobiologyPathologyLab Tech.Industry NewsBioResearch Events

Clinical ChemistryMolecular DiagnosticsHematologyImmunologyMicrobiologyPathologyLab Tech.Industry NewsBioResearch Events Advertise with Us

Abbott Diagnostics

Featured Products

powered by:

HDMZ

Download Mobile App

Trending Articles

Unexplained Liver Disease Diagnosed by Whole-Exome Sequencing

Novel Genes and Pathways Discovered in Celiac Disease

Gene Translocation Marker Linked to Drug Resistance and Poor Prognosis

Novel Software Reduces Variability in ELISA Biomarker Tests

Early Sepsis Detection Test Approved for U.S. Marketing

Low Serum Creatinine Associated with Diabetes Risk

Protein Atlas Accelerates Personalized Medicine in Leukemia Patients

Featured Video

AACC:
71st AACC Annual Scientific Meeting & Clinical Lab Expo

AACC

Recommended on TradeMed

visit trademed.com

Blood Gas Analyzer
Stat Profile Prime

Hemoglobin Assay Kit
MAK115

Immunochromatographic Reader
EASY READER+

Partner Sites

HospiMedica

Smart Pill Bottle Fights Prescription Drug Abuse

Intracranial Coiling Device Assists Aneurysm Embolization

Induced Labor No Costlier than Spontaneous Labor

Collaboration Formed to Advance Digital Patient Safety

Aortic Stenosis Device Improves Valve Hemodynamics

Ebola Rapid Lateral Flow Test Previewed at the 2015 AACC Annual Meeting

By Labmedica International staff writers
Posted on 27 Jul 2015

Image: The AtomoRapid lateral flow immunoassay diagnostic platform (Photo courtesy of Atomo Diagnostics).

Image: The AtomoRapid lateral flow immunoassay diagnostic platform (Photo courtesy of Atomo Diagnostics).

A novel rapid point-of-care assay for the diagnosis of Ebolavirus infection was introduced at the 2015 AACC Annual Meeting & Clinical Lab Expo (Atlanta, GA, USA).

BBI Solutions (Cardiff, United Kingdom), a biotech company that supplies a range of mouse monoclonal antibodies for detecting the Ebola virus, announced from its booth (3665) at the AACC Annual meeting that that it would soon release a rapid test for Ebola in association with the technology transfer company Ploughshare Innovations (Stockbridge, United Kingdom).

The test is built around the highly regarded Atomo Diagnostics (Sydney, Australia) lateral flow technology and provides a result in approximately 20 minutes. Five Ebola antibodies against the Zaire and Sudan strains of Ebolavirus have been tested successfully with this system. BBI Solutions also provides a panel comprising 13 different monoclonal antibodies, to the Zaire and Sudan strains.

The lateral flow test has already been evaluated in the field. In trials in Sierra Leone a 100% detection rate was achieved for 138 participants. At low positive levels the test achieved 100% sensitivity and 92% specificity, and at a high positive, 100% sensitivity and 97% specificity. This performance suggests that the BBI Solutions assay is potentially more sensitive and specific than other lateral flow or dipstick type assays currently available.

Leigh Thomas, chief commercial officer at BBI Solutions, said, “BBI has developed high performance lateral flow tests for some of the world’s leading diagnostic companies for over 25 years. Our expertise and flexibility has allowed us to quickly deploy a team and develop a rapid test in nine months which, based on field testing, promises to have an immediate and positive impact on the Ebola crisis. We are pleased that our test will meet an immediate need in the field and ultimately improve the lives of others.”

Related Links:
2015 AACC Annual Meeting & Clinical Lab Expo
BBI Solutions
Atomo Diagnostics

Latest AACC 2015 News

Channels

Clinical Chemistry

view channel

Image: Research shows that low blood glucose levels in diabetics are tied to hospital readmission (Photo courtesy of Maria Muccioli PhD).

Low Blood Glucose Level in Diabetics Tied to Hospital Readmission

More than 29 million Americans are living with diabetes and an additional 86 million are at risk for developing the disease, In hospitalized patients, low blood sugar, also known as hypoglycemia, is associated... Read more

Image: The TOSOH G8 ion exchange high performance liquid chromatography analyzer (Photo courtesy of Tosoh Bioscience).

Lower HbA1c Levels Seen in Diabetic Liver Disease Patients

Diabetes is a leading cause of liver disease, with cirrhosis responsible for a considerable number of deaths in people with diabetes in the USA. The association is mediated by multiple mechanisms including... Read more

Image: Knee osteoarthritis, also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage (Photo courtesy of Bruce Blaus).

Biomarkers Predict Total Joint Replacements in Osteoarthritis Patients

Osteoarthritis (OA) in major joints ultimately leads to joint failure for which the only curative treatment is total joint replacement. This procedure is associated with risk of complications and approximately... Read more

Image: The INNOTEST PHOSPHO-TAU(181P) is a solid-phase enzyme immunoassay for the quantitative determination of phosphorylated Tau (Phospho-Tau(181P)) in human cerebrospinal fluid (CSF) (Photo courtesy of Fujirebio).

Primary Fatty Amides Produce Blood Test for Alzheimer Disease

Neurodegenerative dementias are characterized by a progressive decline in cognitive function and memory performance. Alzheimer's disease (AD) is the most common of the neurodegenerative dementias making... Read more

Molecular Diagnostics

view channel

Image: A histopathology of castration-resistant prostate cancer (Photo courtesy of Andrew J. Armstrong, MD, ScM).

Genomic Data Affects Prognosis of Advanced Prostate Cancer

Heterogeneity in the genomic landscape of metastatic prostate cancer has become apparent through several comprehensive profiling efforts, but little is known about the impact of this heterogeneity on clinical... Read more

Image: The Affymetrix Genechip 7G scanner analyzes next-generation higher-density arrays (Photo courtesy of Thermo Fisher Scientific).

Assay Stratifies Esophageal Cancer Patients for Treatment

The incidence of esophageal adenocarcinoma (OAC) in the Western world has risen six-fold in the last 40 years with the highest incidence occurring in the UK and there were about 9,200 cases of the disease... Read more

Image: A micrograph of a high-grade serous ovarian carcinoma (Photo courtesy of Wikimedia Commons).

Protein Panel Accurately Differentiates Forms of Ovarian Tumors

A panel of eight proteins was found that distinguishes between the milder endometrioid (EC) and more deadly high-grade serous (HGSC) forms of ovarian cancer with 99.2% accuracy. Ovarian carcinomas are... Read more

Image: A micrograph of urothelial carcinoma of the urinary bladder (Photo courtesy of Baylor College of Medicine).

Clinical Trial Highlights Poor Prognosis for Bladder Cancer Patients

Analysis of the IMvigor 210 clinical trials involving patients with platinum-refractory or cisplatin-ineligible urothelial carcinoma (the most common type of bladder cancer) who were treated with the PD-L1... Read more

Hematology

view channel

Sickle Cell Disease Screening Helps Save Lives of Migrants

Sickle cell disease (SCD) is an inherited disorder that affects the production of hemoglobin, a protein in red blood cells that delivers oxygen to cells throughout the body. This abnormal hemoglobin can... Read more

Image: The Bioanalyzer 2100 system is a microfluidic platform that provides quantitation and quality control of DNA and RNA by capillary electrophoresis (Photo courtesy of Agilent Technologies).

Multiple Myeloma Sequences Reveal Prognostic Immunoglobulin Translocation

Multiple myeloma is the second most common hematological cancer, which affects terminally differentiated antibody secreting B cells, known as plasma cells. Clinical manifestations of myeloma include hypercalcemia,... Read more

Image: The Early Sepsis Indicator kit was designed for use on automated hematology instruments such as the DxH 900 analyzer (Photo courtesy of Beckman Coulter).

Early Sepsis Detection Test Approved for U.S. Marketing

A test for the early detection of sepsis has been approved for marketing in the United States as an in vitro diagnostic product. Sepsis is caused by an inflammatory immune response triggered by an infection.... Read more

Image: The PacBio RS II sequencer uses single molecule, real time (SMRT) sequencing technology (Photo courtesy of Pacific Biosciences).

High-Res Genotyping Improves Survival for Stem Cell Transplantation

Allogeneic hematopoietic cell transplantation (HCT) provides a curative treatment option for individuals with hematologic diseases. Recipients and donors are considered to be compatible or “well matched”... Read more

Immunology

view channel

Image: The V-PLEX Aβ Peptide Panel 1 (6E10) Kit (Photo courtesy of Meso Scale Discovery).

Diagnostic Process Detects Alzheimer’s Years before Symptoms Appear

Alzheimer's disease (AD) pathology is accompanied by misfolding of amyloid-β (Aβ) and tau from monomeric into β-sheet–enriched pathogenic species. This process is suggested to precede about 10 to 15 years... Read more

Simple and Inexpensive Ebola Virus Disease Test Developed

Ebola and Marburg viruses can cause severe bleeding and organ failure, with fatality rates reaching 90% in some outbreaks. The diseases spread through direct contact with bodily fluids of an infected person,... Read more

Image: The FLEXMAP3D Analyzer is an advanced and versatile multiplexing platform (Photo courtesy of Luminex).

Renal Transplant Rejection Assessed by HLA Antigen Bead Assay

Acute cellular rejection (ACR) is associated with complications after kidney transplantation, such as graft dysfunction and graft loss. Early risk assessment is therefore critical for the improvement of... Read more

Image: The Helios CyTOF mass cytometry platform (Photo courtesy of Fluidigm).

Immune Cell Profiling Assay Boosts Use of Mass Cytometry

A new, multiplexed, antibody-based assay for immune cell profiling on its mass cytometry platform has been launched. The assay is comprised of a single-tube assay pre-loaded with 30 metal-labeled antibodies... Read more

Microbiology

view channel

Image: The HumaLoop M: The easy-to-use Loopamp technology for primary and district laboratories (Photo courtesy of Human Diagnostics).

LAMP Malaria Test Detects Less-Diagnosed Species

A new loop-mediated isothermal amplification (LAMP) molecular assay has been developed that can detect Plasmodium vivax, a species of the parasite that causes malaria. Almost all molecular tests currently... Read more

Image: QuantiFERON-TB Gold (QFT) is a simple blood test that aids in the detection of Mycobacterium tuberculosis, the bacteria which causes tuberculosis (TB). QFT is an interferon-gamma (IFN-γ) release assay, commonly known as an IGRA, and is a modern alternative to the tuberculin skin test (Photo courtesy of Qiagen).

Bronchoalveolar Lavage Explored for TB Diagnosis

Tuberculosis (TB) is among the top 10 causes of death worldwide, and the leading cause from a single infectious agent. In 2017, TB caused an estimated 1.3 million deaths among Human Immunodeficiency Virus... Read more

Image: The RealTime HBV is an in vitro polymerase chain reaction (PCR) assay for the quantitation of Hepatitis B Virus (HBV) DNA in human plasma or serum from HBV-infected individuals (Photo courtesy of Abbott Molecular).

Serum HBV RNA Quantification Monitors Chronic Hepatitis B Infection

Chronic hepatitis B viral infection is a global health problem, especially in the Asian-Pacific region. Approximately 1.2 million people in the USA and 350 million people worldwide have Hepatitis B.... Read more

Image: A photomicrograph of human papilloma virus associated oropharyngeal cancer. The tissue has been stained to show the presence of the virus by in situ hybridization (Photo courtesy of Jennifer L. Hunt, MD).

Oral HPV-DNA Persists after Oropharyngeal Cancer Treatment

Head and neck cancers affect some 53,000 people in the USA each year, according to the National Cancer Institute, and human papilloma virus (HPV) has been implicated in many of those cases.... Read more

Pathology

view channel

Image: A photomicrograph showing tumor-infiltrating lymphocytes in a case of colorectal cancer with evidence of high microsatellite instability (MSI-H) on immunostaining (Photo courtesy of Nephron).

Biomarker Predicts Appropriate Immunotherapy for Cancer Patients

Microsatellite instability (MSI) is a hypermutable phenotype caused by the loss of DNA mismatch repair activity. MSI is detected in about 15% of all colorectal cancers; 3% are of these are associated with... Read more

Image: A diagram of evolutionary trajectories of IDH-WT glioblastomas revealing a common path of early tumorigenesis instigated years ahead of initial diagnosis (Photo courtesy of German Cancer Research Center).

Glioblastoma Driver Mutations Appear Long Before Diagnosis

Glioblastomas are the most common high-grade (cancerous) primary brain tumor in adults. They can also occur, rarely, in children. Glioblastomas belong to a group of brain tumors known as gliomas, as they... Read more

Image: A histopathology of hepatocellular carcinoma: a mononuclear inflammatory cell infiltrate extends from portal areas and disrupts the limiting plate of hepatocytes which are undergoing apoptosis, the so-called interface hepatitis of chronic active hepatitis. In this case, the hepatitis B surface antigen (HBsAg) and hepatitis B core antibody (HBcAb) were positive (Photo courtesy of University of Utah Medical School).

Virus-Associated Liver Cancer Detected by Blood Tests

Viral infection with either hepatitis C virus (HCV) or Hepatitis B virus (HBV) is the chief cause of liver cancer in the world today, accounting for 80% of hepatocellular carcinoma (HCC).... Read more

EBUS More Reliable Than Histology for Cancer Diagnoses

Radial probe endobronchial ultrasound (EBUS) is a minimally invasive procedure that improves localization of peripheral pulmonary lesions. Cytology samples of the suspect lesion site collected by radial... Read more

Lab Tech.

view channel

Image: The Atellica CH Enzymatic Hemoglobin A1c (A1c_E) Assay (Photo courtesy of Siemens Healthineers).

Siemens Healthineers Hemoglobin A1c Test Now Available on Atellica Solution

The Atellica CH Enzymatic Hemoglobin A1c (A1c_E) Assay is an easy-to-implement chemistry test, offering precise and accurate results for diabetic patient management. The A1c_E assay is less prone to... Read more

Image: A nanoelectronics assay: stressed blood cells could be a biomarker for chronic fatigue (Photo courtesy of The Scientist).

Biomarker Test Developed for Chronic Fatigue Syndrome

Myalgic encephalomyelitis, or chronic fatigue syndrome (ME/CFS), is a serious condition that may affect up to 2.5 million people in the USA. Symptoms include extreme tiredness, difficulty sleeping, trouble... Read more

Flow Cytometry Leukemia/Lymphoma Antibody Panel Receives Approval

A panel of immune-phenotyping flow cytometer reagents that identifies both lymphoid and myeloid cell lines has been granted diagnostic marketing clearance by the [U.S.] Food and Drug Administration to... Read more

Image: Liquid handling products from Hecht-Assistant (Photo courtesy of Glaswarenfabrik Karl Hecht).

Glaswarenfabrik Karl Hecht Celebrates 100-year Anniversary

In 1919, Karl Hecht laid the foundation for the Glaswarenfabrik in Sitzendorf-Unterweißbach in Thuringia, Germany. Over the decades the company continuously specialized in production and distribution of... Read more

Industry News

view channel

Image: The DxA total lab automation solution (Photo courtesy of Beckman Coulter).

Beckman Coulter Introduces New Total Laboratory Automation Solution

Beckman Coulter’s (Brea, CA, USA) latest addition to its automation portfolio, the DxA 5000 total laboratory automation solution has achieved European CE Mark and China Food and Drug Administration approval.... Read more

Image: The Multi-Test VITROS chemistry product slides (Photo courtesy of Ortho Clinical Diagnostics).

Ortho Clinical Diagnostics Presents Cardiac Advances at EuroMedLab 2019

Ortho Clinical Diagnostics (Raritan, NJ, USA) sponsored an educational workshop on high-sensitivity troponin assays and presented five scientific posters at EuroMedLab 2019, the 23rd IFCC-EFLM European... Read more

Image: The global point of care diagnostics/testing market is expected to reach almost USD 23 billion by 2025 (Photo courtesy of iStock).

Global POC Diagnostics/Testing Market to Reach USD 22.8 Billion by 2025

The global point of care (POC) diagnostics/testing market size is expected to grow at a CAGR of 3.3% over the forecast period 2019-2025 to reach USD 22.8 billion by 2025, driven by the ability of POC tests... Read more

Global Automated Immunoassay Analyzer Market Driven by Increase in Applications

The global automated immunoassay analyzer market is expected to achieve significant growth over the coming years, driven by innovations in the existing products and increased clinical applications of these systems.... Read more

BioResearch

view channel

$Image: A micrograph showing retinal cells derived from a patient\'s skin cells, via induced pluripotent stem cells. The cells are organized in a polygonal shape and have taken on characteristic pigmentation (Photo courtesy of the University of California, San Diego).$

Laboratory Model Reveals Genetic Risk Loci for AMD

Eye disease researchers used advanced stem cell technology to create a laboratory model of age-related macular degeneration (AMD), which enabled in-depth analysis of the genetics underlying the syndrome.... Read more

Image: A micrograph showing four-cell stage mouse embryos (Photo courtesy of Kirill Makedonski, the Hebrew University of Jerusalem).

Gene Set Isolated in Transformation of Skin Cells into Embryonic Tissues

A team of developmental biologists identified a set of five genes that is capable of transforming skin cells into pluripotent stem cells and then into all three of the cell types that comprise the early... Read more

Image: A micrograph of a mucinous ovarian carcinoma (Photo courtesy of Wikimedia Commons).

Large GWAS Pinpoints Ovarian Cancer Risk Genes

Results of a large genome-wide association study identified 34 genes that are associated with an increased risk for developing the earliest stages of ovarian cancer. The current study, which was carried... Read more

Image: A micrograph of a colonic biopsy showing inflammation of the large bowel in a case of inflammatory bowel disease (Photo courtesy of Wikimedia Commons).

Blood Test Distinguishes between Forms of Inflammatory Bowel Disease

A recently developed blood test distinguishes between mild and severe forms of inflammatory bowel disease and is potentially a step towards realizing personalized therapy for the syndrome.... Read more

LabMedica

About Us
Advertising Info
Subscription
Client Login
Privacy Policy
Cookie Policy
Journal Info
Contact Us

Channels

Clinical Chemistry
Molecular Diagnostics
Hematology
Immunology
Microbiology
Pathology
Lab Tech.
Industry News
BioResearch
Events

Features

Events Product Showcase LinkXpress Whitepapers archive Video Library

Partner Sites

TradeMed.com HospiMedica.com Globetech.net

Copyright © 2000-2019 Globetech Media. All rights reserved.

MOBILE | FULL SITE