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Pathology

Image: Peripheral blood smear from a patient with chronic lymphocytic leukemia (CLL). The lymphocytes with the darkly staining nuclei and scant cytoplasm are the CLL cells (Photo courtesy of VashiDonsk).

Second Malignancy Risk Higher for Some Leukemia Survivors

 Chronic lymphocytic leukemia (CLL) is the most common leukemia diagnosis in adults, with favorable outcomes in majority of patients and a 5-year survival of around 85%. A large proportion of CLL patients may never require treatment, requiring only ongoing surveillance. More...
25 Nov 2019
Image: The Oncotype DX test is a genomic test that analyzes the activity of a group of genes that can affect how a cancer is likely to behave and respond to treatment (Photo courtesy of Michael Jarrett/Genomic Health)

Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants

 A single normal cell randomly acquires a series of mutations that allows it to proliferate and to be transformed into a cancer cell (i.e., founding clone), which initiates tumor progression and recurrence. More...
25 Nov 2019
Image: A simple blood test could diagnose breast cancer up to five years before symptoms occur. The presence of autoantibodies, that compliment tumor-associated antigens, help to diagnose breast cancer earlier (Photo courtesy of Oncology Central).

Innovative Blood Test Aids Early Detection of Breast Cancer

 A blood test is being developed that could help detect breast cancer five years before any symptoms become apparent. This method would also be less uncomfortable and more cost effective than traditional mammograms. More...
25 Nov 2019
Image: Retinoblastoma is cancer of the eye and cannot be biopsied. Aqueous humor is superior to blood to diagnose retinoblastoma (Photo courtesy of Aravind Eye Hospital).

Aqueous Humor Is Superior to Blood to Diagnose Retinoblastoma

Retinoblastoma is a cancer that forms in the light-detecting cells in the back of the eye. It often appears in children under two years of age and can lead to blindness or eye removal. Most cancers are biopsied and studied so that medical scientists can design targeted treatments. More...
25 Nov 2019
Image: The HISCL-5000 is a fully automated immunoassay analyzer with a throughput of 200 tests per hour. The incubation time for each parameter is 17 minute and allows each laboratory to achieve maximum efficiency and productivity (Photo courtesy of Sysmex Corporation).

Automated Immunoassay Systems Evaluated for KL‐6 Antigen Quantification

Interstitial lung disease (ILD) is a group of diseases characterized by various forms of pulmonary interstitial inflammation and fibrosis, which are usually chronic, progressive, and fatal, causing death 2‐5 years after diagnosis in most patients. More...
20 Nov 2019
Image: Histopathology of prostate cancer: crystalloids (bright eosinophilic rhomboid to prismatic structures, seen in ~40% cancer) and amorphous eosinophilic secretions (Photo courtesy the American Urological Association).

High Levels Of Blood Hormones Raise Prostate Cancer Risk

Men with higher levels of 'free' testosterone and a growth hormone in their blood are more likely to be diagnosed with prostate cancer. Other factors such as older age, ethnicity and a family history of the disease are already known to increase a man's risk of developing prostate cancer. More...
11 Nov 2019
Image: A scanning electron micrograph (SEM) of prostate cancer cells (Photo courtesy of Sloan Kettering Institute).

Prostate Cancer Methylation Levels Linked to Epigenetic Profiles

Prostate cancer is cancer that occurs in the prostate, a small walnut-shaped gland in men that produces the seminal fluid that nourishes and transports sperm. Prostate cancer is one of the most common types of cancer in men. More...
07 Nov 2019
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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