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Immunology

Image: The RF direct latex tests for the detection of rheumatoid factor (RF) in serum (Photo courtesy of VedaLab).

Specificity of Rheumatoid Factor Detected by Latex Fixation Compared

Rheumatoid arthritis is a chronic inflammatory and autoimmune disorder that can affect more than just the joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels. More...
02 Sep 2020
Image: Mass cytometry by time of flight uses CyTOF technology to enable deep profiling of translational and clinical samples across a range of cell surface and intracellular markers (Photo courtesy of University of Virginia).

Adaptive Immune Cells in Ulcerative Colitis Revealed by Single-Cell Analyses

Inflammatory bowel disease encompasses a spectrum of complex intestinal disorders characterized by dysregulated innate and adaptive immune responses to gut microbiota in genetically susceptible hosts. More...
01 Sep 2020
Image: De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection (Photo courtesy of UT Southwestern Medical Center).

Cancer-Associated T Cell Receptors Evaluated for Malignancy Detection

A key goal in oncology is diagnosing cancer early, when it is more treatable. Despite decades of progress, early diagnosis of asymptomatic patients remains a major challenge. Most methods for this involve detecting cancer cells, but a different approach, focused on the body’s immune response. More...
31 Aug 2020
Image: Photomicrograph of Hodgkin lymphoma (HL), from a fine needle aspiration of a lymph node, which shows a mixture of cells common in HL: Eosinophils, Reed-Sternberg cells, Plasma cells, and Histocytes (Photo courtesy of Nephron).

Hodgkin Lymphoma Therapy Response Linked to T-Cell Receptor Repertoire

Hodgkin lymphoma (HL) is a type of lymphoma in which cancer originates from a specific type of white blood cells called lymphocytes. Symptoms may include fever, night sweats, and weight loss. Often there will be non-painful enlarged lymph nodes in the neck, under the arm, or in the groin. More...
27 Aug 2020
Image: Schematic diagram of the OvCa-Chip microsystem that recreates vascular endothelium–mediated platelet extravasation in ovarian cancer (Photo courtesy of Texas A&M College of Engineering).

Microfluidic Device Explores Ovarian Cancer Interactions

In many cancers, platelet interactions with circulating tumor cells and their role in metastasis have been studied extensively. In ovarian cancer, platelet extravasation into the tumor and resulting metastasis is thought to be regulated mostly by the vascular endothelium. More...
26 Aug 2020
Nucleic acid amplification testing-based assay (NAT) improves the surveillance system and prevent transfusion-transmitted malaria in blood banks (Photo courtesy of University of Cambridge).

Blood Bank NAT-Based Assay Prevents Transfusion-Transmitted Malaria

Blood transfusion is an essential component of health care, which saves millions of lives across the world. The screening of blood donors for transfusion-transmissible agents is crucial in reducing risks of transfusion of infected units. More...
20 Aug 2020
The Gallios 10-color/3-laser flow cytometer (Photo courtesy of Beckman Coulter).

Prostate Cancer Identified By Profiling Immune Cell Subsets

With an estimated 1.8 million new cases in 2018 alone, prostate cancer is the fourth most common cancer in the world. Diagnosing the disease early increases the chances of survival, but this cancer remains difficult to detect. More...
19 Aug 2020
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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