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Immunology

Image: Scientists have greatly boosted the amount of information that can be obtained using Seq-Well S3, a technique for rapidly sequencing RNA from single cells (Photo courtesy of MIT).

Novel Method Reclaims Resolution of Single-Cell RNA-Seq

Single-cell RNA sequencing (scRNA-seq) is a powerful tool to characterize cells. Current scRNA-seq platforms, despite offering high throughput, are inefficient and provide low resolution among distinct cell states and molecular features. More...
28 Oct 2020
Image: The EUROPattern Microscope Live: Ultrafast fluorescence microscopy that automatically detects anti-neutrophil cytoplasmic antibodies (Photo courtesy of EUROIMMUN AG).

Methods for Automated Anti-Neutrophil Cytoplasmic Antibodies Compared

The detection of anti-neutrophil cytoplasmic antibodies (ANCA) by indirect immunofluorescence assays (IFA) is of diagnostic importance in vasculitis and some other inflammatory diseases. More...
21 Oct 2020
Image: The AFIAS-6 (AFIAS-automated fluorescent immunoassay system) is an automated fluorescent immunoassay system that uses blood, urine, and other samples to measure quantitatively or semi-quantitatively the concentration of targeted analyte (Photo courtesy of Boditech Med Inc).

New Diagnostic Tests for Rotavirus and Norovirus Infections Evaluated

Acute gastroenteritis is one of the most impactful and common infectious diseases, accounting for millions of deaths annually in young children. Rotavirus and norovirus are leading causes of acute viral gastroenteritis spread through fecal to oral transmission. More...
21 Oct 2020
Image: Photomicrograph showing tumor-infiltrating lymphocytes in colorectal carcinoma which are suggestive of microsatellite instability (Photo courtesy of Nephron)

Lymphocytic Infiltration Explored as Biomarker for Stable Colorectal Tumors

Identifying stage II patients with colorectal cancer (CRC) at higher risk of progression is a clinical priority in order to optimize the advantages of adjuvant chemotherapy while avoiding unnecessary toxicity. A remarkable feature of CRC is the difference in prognosis of patients diagnosed at early versus late stages of the disease. More...
15 Oct 2020
Image: The BD FACSymphony A5 flow cytometer (Photo courtesy of BD Biosciences).

MAIT Cell Activation Dynamics Associated with COVID-19 Disease Severity

The balance between protective versus pathological immune responses in COVID-19 has been a concern since the onset of the pandemic. SARS-CoV-2 infection can lead to acute respiratory distress syndrome (ARDS), a condition characterized by aggressive inflammatory responses in the lower airways. More...
13 Oct 2020
Image: LIAISON XL is a fully automated chemiluminescence analyzer, performing complete sample processing as well as measurement and evaluation (Photo courtesy of Diasorin).

Serum Thyroglobulin Assays Compared for Differentiated Thyroid Carcinoma

Measurement of serum thyroglobulin (Tg) plays a key role in the post‐thyroidectomy management of differentiated thyroid carcinoma (DTC). In this context, the performance of new‐generation thyroglobulin assay has clinical implications in the follow‐up of DTC patients. More...
05 Oct 2020
Image: DPP Ebola Antigen System is a 15 minute rapid test for detection of Ebola Virus Specific Antigen (Photo courtesy of Chembio Diagnostic Systems).

Performance Compared for Three Ebola Rapid Diagnostic Tests

Ebola is a rare but deadly virus that causes fever, body aches, and diarrhea, and sometimes bleeding inside and outside the body. As the virus spreads through the body, it damages the immune system and organs. Ultimately, it causes levels of blood-clotting cells to drop. More...
01 Oct 2020
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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