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Clinical Chemistry

Image: Elecsys Pro-BNP II Gen Assay may identify higher natriuretic peptide levels during early pregnancy were better for maternal blood pressure (Photo courtesy of Biolab Diagnostics)

High NT-proBNP Paradoxically Shows Lower Risk in Early Pregnancy

Hypertensive disorders of pregnancy are associated with future cardiovascular disease, perhaps because of subclinical cardiac dysfunction before pregnancy leading to impaired adaptation to pregnancy. More...
03 Feb 2022
Image: Enzyme-Free Sensor (Photo courtesy of Integrated Graphene)

New, Enzyme-Free Glucose Monitoring Sensor Solution Could Find Applications in Range of POC Diagnostics

Researchers have developed a new glucose sensor that is cheaper and more robust than current systems, opening up the possibility of taking the underlying applied methodology to a vast range of similar point-of-care diagnostics. More...
03 Feb 2022
Image: The Beckman AU5800 automatic analyzer (Photo courtesy of Beckman Coulter)

ALT/AST Ratio Is an Independent Risk Factor for Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) is defined as a state of impaired glucose tolerance first being discovered during pregnancy. GDM increases the risk of pregnancy complications and adverse perinatal outcomes, such as pregnancy-induced hypertension, preeclampsia, abortion, premature delivery, premature ruptures of membranes, and large for gestational age infants. More...
02 Feb 2022
Image: The Proprium Fibro-CHI Diagnostic ELISA Kit for the quantification of Chitinase 3-Like 1 (CHI3L1) in serum and plasma (Photo courtesy of Proprium Biotech Company Limited)

Diagnostic Value of Serum CHI3L1 in Hepatocellular Carcinoma Explored

Primary liver cancer is the sixth diagnosed cancer and the fourth cause of cancer-related death worldwide. Hepatocellular carcinoma (HCC) is the major pathological category and comprises a 75%–85% incidence of primary liver cancer cases. More...
02 Feb 2022
Image: Proteomic Noninvasive Biomarkers Discovered Associated with Sport-Related Concussions (Photo courtesy of The Lancet)

Proteomic Noninvasive Biomarkers Associated with Sport-Related Concussions

Sport-related concussions affect millions of individuals across the USA each year, and current techniques to diagnose and monitor them rely largely on subjective measures. Concussion can be frustratingly hard to diagnose and track. More...
26 Jan 2022
Image: The Homeostasis Model Assessment (HOMA) may have utility as a single-time-point measurement to stratify risk of type 1 diabetes development in autoantibody-positive individuals (Photo courtesy of Adobe Stock)

HOMA2-B Assessed for Type 1 Diabetes Risk

Methods to identify individuals at highest risk for type 1 diabetes are essential for the successful implementation of disease-modifying interventions. Simple metabolic measures are needed to help stratify autoantibody-positive (Aab+) individuals who are at risk of developing type 1 diabetes. More...
26 Jan 2022
Image: The SENTIFIT-FOB Gold test is a latex agglutination immunoturbidimetric assay for quantitation of hemoglobin in feces (Photo courtesy of Sentinel Diagnostics)

Fecal Immunochemical Test for Hemoglobin Evaluated on Automated System

Colorectal cancer (CRC) is the third most common cancer in men and women and has the second most mortality rate worldwide. Most of the new CRC cases are found in patients presenting with symptoms in primary health care, such as changes in bowel habit and red blood in the feces. More...
25 Jan 2022
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.

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