Hemolytic, Icteric, and Lipemic Samples Automatically Detected and Managed

The effects of preanalytical factors can account for up to 70% of a clinical laboratory's errors.

The new generation of coagulation systems automatically detects and manages hemolytic, icteric, and lipemic samples prior to test run. Using preanalytical sample integrity (PSI) technology, the Sysmex CS-2000i system from Siemens Healthcare Diagnostics (Deerfield, IL USA) provides extra operator support by identifying and automatically managing potentially problematic samples prior to analysis. To further maximize workflow, intuitive user-defined software automatically handles results based on user-defined criteria.

The system's simultaneous multiwavelength analytical scanning uses up to five different wavelengths to analyze clotting reactions: 340 nm, 405 nm, 575 nm, 660 nm, and 800 nm. The intelligent system design reduces the need for visual reads and selects the optimal wavelength to reduce the effect of interfering substances. The wide optical spectrum enables measurement of light transmittance over the entire course of the clot formation, not just the end. Thus, atypical reaction patterns can be easily identified to aid in determining the correct coagulation reaction result for patients with unusual in vitro clot reactions such as sepsis or disseminated intravascular coagulation (DIC).

The Sysmex CS-2100i system offers an advanced, third-generation cap-piercing option, intuitive software, troubleshooting software support, and minimal user maintenance. The refrigerated reagent table allows for long on-board stability and reduces the need to remove and place reagents each day while tilted reagent vial positions with positive barcode identification reduce reagent waste. In addition, the robust design with rotating reagent table and short pipettor movements rapidly processes samples and increases system reliability.

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