Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
GLOBE SCIENTIFIC, LLC

DIASORIN

DiaSorin develops, produces and commercializes diagnostic tests for a wide range of clinical areas. The company’s tes... read more Featured Products: More products

Download Mobile App




Molecular Multiplexing Panel for Blood Culture Identification Enables Targeted Treatment Decisions

By LabMedica International staff writers
Posted on 03 Oct 2024

Each year, approximately 250,000 patients in the US are diagnosed with bloodstream infections (BSIs). More...

Sepsis resulting from BSIs has an average mortality rate of 16-40%, and any delays in initiating appropriate treatment increase patient risk. Sepsis is also the most expensive cause of hospitalization in the US, accounting for more than USD 20 billion annually. Gram-negative bacteremia represents about 30% of all positive blood cultures, and each pathogen along with its resistance genes often necessitates adjustments to the initial empiric therapy. Now, a multiplex blood culture panel can improve the microbiological diagnosis of BSIs by detecting Gram-negative bacteria and relevant resistance genes, thereby enhancing standard-of-care workflows and reducing operational costs.

Diasorin’s (Saluggia VC, Italy) LIAISON PLEX Gram-Negative Blood Culture Assay enables clinicians to make more targeted treatment decisions within two hours after the Gram stain by quickly identifying pathogens and detecting resistance determinants. The assay utilizes Diasorin’s proprietary NanoGrid technology, a unique non-amplified molecular chemistry designed to reduce false positives. Because this panel is based on Gram stain results and focuses exclusively on Gram-negative pathogens, it enhances diagnostic stewardship and helps control treatment costs compared to current market solutions that include a broader range of pathogens associated with bacteremia, regardless of Gram stain results.

Diasorin has submitted a 510(k) premarket notification to the U.S. Food and Drug Administration (FDA) for the LIAISON PLEX Gram-Negative Blood Culture Assay, which is the second of three molecular multiplex panels for blood culture identification on the LIAISON PLEX instrument. Previously, Diasorin received FDA clearance for the LIAISON PLEX Respiratory Flex Assay in March 2024 and the LIAISON PLEX Yeast Blood Culture Assay in June 2024.

“We firmly believe that LIAISON PLEX provides unique flexibility by enabling clinicians to select the most appropriate blood panel for their patients. This ensures that clinical laboratories can generate reliable results more quickly and cost-effectively,” said Angelo Rago, President of Luminex. “We are committed to developing critically important tests for the platform to expand its application to a broader range of healthcare needs.”

Related Links:
Diasorin


New
Gold Member
Serological Pipets
INTEGRA Serological Pipets
Serological Pipet Controller
PIPETBOY GENIUS
New
Celiac Disease Test
Anti-Gliadin IgG ELISA
New
DNA/RNA Extraction/Purification Kit
Nucleic Acid Extraction or Purification Kit
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: A simple blood test could replace surgical biopsies for early detecion of heart transplant rejection (Photo courtesy of Shutterstock)

Blood Test Detects Organ Rejection in Heart Transplant Patients

Following a heart transplant, patients are required to undergo surgical biopsies so that physicians can assess the possibility of organ rejection. Rejection happens when the recipient’s immune system identifies... Read more

Pathology

view channel
These images illustrate how precision oncology Organ Chips recapitulate individual patients’ responses to chemotherapy (Photo courtesy of Wyss Institute at Harvard University)

Cancer Chip Accurately Predicts Patient-Specific Chemotherapy Response

Esophageal adenocarcinoma (EAC), one of the two primary types of esophageal cancer, ranks as the sixth leading cause of cancer-related deaths worldwide and currently lacks effective targeted therapies.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.