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Liquid Tumor Marker Control Covers Fifteen Cancer Antigens

By LabMedica International staff writers
Posted on 04 Dec 2012
A new multianalyte liquid tumor marker control covers a total of 15 commonly tested and esoteric cancer antigens and tumor markers. More...
The inclusion of assayed, instrument specific target values enables laboratories to effectively monitor their accuracy and precision.

The Liquid Tumor Marker Control includes Alpha-fetoprotein (AFP), Beta-2- Microglobulin, CA15-3, CA19-9, CA27-29, CA72-4, CA125, Carcinoembryonic Antigen (CEA), Cyfra 21-1, Ferritin, Human Chorionic Gonadotropin (hCG), Neuron-specific Enolase (NSE), Prostate Specific Antigen Free (PSA Free), Prostate Specific Antigen Total (PSA Total), and Thyroglobulin.

Requiring no preparation, the liquid ready-to-use format is convenient for laboratory staff. The material can be easily shipped and stored at +2–8 °C. Liquid stable controls eliminate the need for reconstitution and reduce the amount of human handling necessary. The user friendly 6 x 3 mL pack size and open vial stability of 30 days at +2–8 °C for all analytes listed significantly helps to minimize waste and keep running costs low.

Released by Randox (Crumlin, United Kingdom) the Acusera immunoassay controls use serum that is 100% human in origin, providing a matrix similar to the patient sample but also reducing antibody cross reactivity and the possibility of control values shifting when reagent batch is changed. Three levels of control are available with all analytes including PSA present at desirable levels. Clinically relevant PSA levels ensure the ratio of free to bound PSA is typical of that found in cancer patients.

An interlaboratory data management program called Acusera 24.7 Live Online was designed to monitor analytical performance, interpret QC results, and improve the effectiveness of quality control. With Acusera 24.7 users benefit from online access anytime, peer group data generated from thousands of laboratories every 24 hours, fully interactive charts and reports and automatic import of QC data direct from the Laboratory Information Management Systems (LIMs) or instrument via Acusera 24.7 Connect.

As a true third party control, laboratories can use the Acusera liquid tumor marker control to independently assess analytical performance. Fully assayed, instrument specific target values and ranges are provided for many common clinical chemistry and immunoassay systems.

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