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AKI生物标记物的反应快于其它状态标记物

By LabMedica International staff writers
Posted on 01 Apr 2011
一种诊断急性肾损伤(AKI)的新型生物标记物的反应先于其它肾状态的标记物,如血清肌酐,且反应与损伤程度成正比。

这种新型的快速NGAL检验只用几滴血浆或尿液,10分钟就可给出结果,从而解决了迅速确定肾损伤的普遍需求。该检验提供了一种新的鉴定途径,可在检测出严重急性肾损伤(AKI)的24-72小时前发现有此风险的病人。

NGAL检验的设计用途是在不同品牌化学分析仪的开放通道上运行,使大多数实验室方便而容易地确定肾损伤。NGAL水平在肾损伤后急速上升,所以已被用于各种临床场合,如重症监护、急诊医疗、肾移植和涉及静脉内对比度增强剂与其它肾毒性药物的过程。

BioPorto Diagnostics公司(Gentofte, Denmark; www.bioporto.com)刚刚在欧洲发布获得CE标志的NGAL检验。这意味着该公司开始向欧洲的医院销售,医生将使用该工具来克服急性肾损伤的有害作用。

2010年11月,BioPorto公司预发布了NGAL检验,但只用于科研,此后该产品在欧洲、美国和东南亚的指定医院成功通过了测试。

"有了CE标志,我们就可以开始在欧盟销售,但CE标志也是迈向世界市场的重要一步,"BioPorto公司CEO Thea Olesen说。她又补充说:"在加拿大和印度等其它关键市场,当地的审批取决于NGAL检验的CE标志。"

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BioPorto Diagnostics >> www.bioporto.com
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