We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
GLOBE SCIENTIFIC, LLC

Download Mobile App




血液生物标志物可预测心血管疾病

By LabMedica International staff writers
Posted on 04 Jul 2010
一种简单的血检可帮助识别出有心脏病风险的病人的血管炎症问题。

血液中发现的一种酶绝大部分会与低密度脂蛋白(LDL)结合,可作为冠状动脉血管疾病的风险因素给出指示。脂蛋白相关的磷脂A2 (Lp-PLA2)的活性上升经常会导致动脉硬化,脂蛋白相关的磷脂A2也被称为血小板活化因子乙酰水解酶(PAF-AH)。它被认为是脂肪斑恶化和破裂的关键,脂肪斑会堵塞冠状动脉血管,导致心脏病发作。

LpPLA2的活性和质量在进行动脉X光摄影(血管造影)的高危病人身上进行衡量,动脉X光摄影是一种医疗成像技术,可以看见血管和心室的内腔。有336名白种人和224名非裔美国人参与了研究。

研究结果显示,LpPLA2活性在患有冠状动脉心脏疾病的白人和非裔美国人身上都增加了,不过只有后者的LpPLA2指数可以独立预测冠状动脉血管疾病。

"动脉X光摄影是高度有效的,不过作为普通筛查被认为是太危险,而且费用高”,加州大学戴维斯分校(UC Davis, Sacramento, CA, USA; www.ucdmc.ucdavis.edu)首席科学家Lars Berglund医生说。所以,可以可靠预测心脏病发作的简单血检方法会比创伤性过程更易被采用。LpPLA2检测已经被广泛采用,关于这种酶以及针对更大范围人群的其他炎症成份的进一步研究将使得科学家们能够诊断并预测出不同种族和不同民族的心脏病。

研究公布在2010年《临床内分泌学和代谢杂志》上。研究中所提供的信息将使医生们能够针对病人特殊需要进行治疗。

Related Links:
加州大学戴维斯分校>>> www.ucdmc.ucdavis.edu

Gold Member
Troponin T QC
Troponin T Quality Control
3-Part Differential Hematology Analyzer
Swelab Alfa Plus Sampler
New
Biochemistry Analyzer
Chemi+ 8100
New
Glucose Tolerance Test
NERL Trutol
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: The tip optofluidic immunoassay platform enables rapid, multiplexed antibody profiling using only 1 μL of fingertip blood (Photo courtesy of hLife, DOI:10.1016/j.hlife.2025.04.005)

POC Diagnostic Platform Performs Immune Analysis Using One Drop of Fingertip Blood

As new COVID-19 variants continue to emerge and individuals accumulate complex histories of vaccination and infection, there is an urgent need for diagnostic tools that can quickly and accurately assess... Read more

Microbiology

view channel
Image: The LIAISON PLEX® Gram-Positive Blood Culture Assay runs on the on the LIAISON PLEX instrument (Photo courtesy of Diasorin)

Blood Culture Assay Enhances Diagnostic Stewardship Through Targeted Panel Selection

Each year, around 250,000 individuals in the US are diagnosed with bloodstream infections (BSIs). Sepsis caused by these infections carries a mortality rate ranging from 16% to 40%, and any delay in administering... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.