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Pathology

Image: Histological features of COVID-19 lungs (Photo courtesy of the University of Trieste).

COVID-19 Lung Damage Caused by Persistence of Abnormal Cells

Several uncertainties still relate to the involvement of other organs in COVID-19. Besides indirect multi-organ injury, a few reports have suggested the possibility of direct injury caused by viral replication in brain, heart and kidney. More...
19 Nov 2020
Image: The CELLSEARCH CTC System is the first and only clinically validated, FDA-cleared system for identification, isolation, and enumeration of circulating tumor cells (CTCs) from a simple blood test (Photo courtesy of Menarini Silicon Biosystems).

Circulating Tumor Cell-Count Drives Therapy Choice for Breast Cancer

The choice between chemotherapy and endocrine therapy as first-line treatment for hormone receptor–positive, ERBB2 (also known as HER2)-negative metastatic breast cancer is usually based on the presence of clinical features associated with a poor prognosis. More...
18 Nov 2020
DIASOURCE (A Biovendor Company)
Image: The AbsoluteIDQ p180 kit provides scientists with highly reproducible metabolomics data to confidently obtain detailed knowledge about the metabolic phenotypes in their studies (Photo courtesy of BIOCRATES Life Sciences).

Metabolomics Profiles Associated with Diabetic Retinopathy

Diabetic retinopathy (DR), like diabetic neuropathy and nephropathy, is a common complication of diabetes. It is the leading cause of loss of vision in diabetic patients. Long-standing disease, along with hyperglycemia, hyperlipidemia, hypertension, and genetic factors, is a major risk factor of diabetes retinopathy. More...
16 Nov 2020
Image: Autoantibody order, timing helps predict genetically susceptible children most likely to get type 1 diabetes (Photo courtesy of the Morsani College of Medicine).

Autoantibody Timing Predicts Genetically At-Risk Children for Diabetes

While antibodies are molecules produced by the body's immune system to detect and destroy specific viruses, bacteria and other harmful substances, autoantibodies are antibodies that target a person's own healthy tissue. In the case of type 1 diabetes (T1D), a misdirected autoimmune response attacks the pancreas and gradually destroys the organ's insulin-producing beta cells. More...
11 Nov 2020
Image: The Qiagen miRNeasy serum/plasma miRNA isolation kit (Photo courtesy of Qiagen).

Molecular Blood Test Kit Detects Gastric Cancer Early

Gastric cancer (GC) is the fifth most common cancer and the third-leading cause of cancer deaths worldwide. GC mortality is high due to late presentation. In most countries, mass screening is neither feasible nor cost-effective because such screening methods are costly and invasive, with poor compliance. More...
09 Nov 2020
Image: The HM-JACKarc analytical system is a compact bench top system that uses Integrated Sphere Latex Turbidimetry to measure fecal hemoglobin concentration using a highly sensitive latex reagent coated with polyclonal antibodies to human hemoglobin (Photo courtesy of Hitachi Chemical Diagnostics Systems).

Fecal Immunochemical Test Assessed in Suspected Colorectal Cancer

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. More...
05 Nov 2020
Image: A neural stem cell model of sporadic congenital hydrocephalus (Photo courtesy of Yale University School of Medicine).

Genetic Alterations Associated with Sporadic Congenital Hydrocephalus

Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with neurosurgical CSF diversion with high morbidity and failure rates. More...
02 Nov 2020
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.

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