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Microbiology

Image: A photomicrograph of the bone marrow of a pediatric patient with acute myeloid leukemia (Photo courtesy of St. Jude Children\'s Research Hospital).

Genetically Encoded Sensor Isolates Hidden Leukemic Stem Cells

All stem cells can multiply, proliferate and differentiate and because of these qualities, and leukemic stem cells are the most malignant of all leukemic cells. Understanding how leukemic stem cells are regulated has become an important area of cancer studies. More...
26 Mar 2019
Image: The ZymoBIOMICS DNA Mini Kit is designed for purifying DNA from any sample input that is immediately ready for microbiome or metagenome analyses (Photo courtesy of Zymo Research).

Oral Bacteria Linked to More Aggressive Tumors

Pancreatic cystic neoplasms (PCN) are increasingly detected in the general population. They comprise a clinically challenging entity with potential to progress to invasive cancer. The disease is often discovered late, which means that in most cases the prognosis is poor. More...
26 Mar 2019
DIASOURCE (A Biovendor Company)
Image: A scanning electron micrograph (SEM) showing long sickle cell in front of more disc-shaped normal red cell (Photo courtesy of the Wellcome Trust).

Infections Identified in Pediatric Sickle Cell Disease

Sickle cell anemia is a hereditary disorder of autosomal recessive inheritance that is characterized by sickle-shaped red blood cells. It is the most common type of hemoglobinopathy and is the result of a mutation in the β-globin chain gene that results in creating sickle hemoglobin (HbS) instead of the normal adult hemoglobin (HbA). More...
21 Mar 2019
Image: A paper-based microfluidic device enables multiplex LAMP-based detection of malaria in blood (Photo courtesy of University of Glasgow).

Paper-Based Technology Enables Malaria Detection

Populations living in remote rural communities would benefit from rapid, highly sensitive molecular, DNA-based diagnostics to inform the correct and timely treatment of infectious diseases. More...
21 Mar 2019
Image: The CFX96 real-time polymerase chain reaction detection system (Photo courtesy of Bio-Rad).

Fast Diagnosis of Sporotrichosis Based on RT-PCR

Sporotrichosis is a subacute or chronic infectious disease caused by dimorphic fungi of Sporothrix spp. The genus Sporothrix consists of several species with different geographic distributions, virulence, and antifungal susceptibilities, making species-level identification necessary. More...
21 Mar 2019
Image: The cobas e 602 integrates immunoassay and clinical chemistry testing on a single platform (Photo courtesy of Roche).

Efficacy Investigated for Electrochemiluminescence Immunoassay

Syphilis caused by Treponema pallidum is a chronic bacterial infection. T. pallidum cannot be cultured in vitro, and new molecular tests for syphilis are unlikely to replace serology in the short term because they are fairly expensive and require sophisticated equipment. More...
20 Mar 2019
Image: The Host Response to Microbe Analysis platform can be tailored for different pathogens including Salmonella enterica (Photo courtesy of Wikipedia).

New AI-driven Toolkit Provides Insight into Infectious Pathogens

Scientists at the Francis Crick Institute and UCL have developed a new AI-driven platform that can analyze how pathogens infect human (‘host’) cells with the precision of a trained biologist. More...
20 Mar 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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