We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
Sekisui Diagnostics

Download Mobile App




Microscopio de rayos X de súper-resolución permite la observación del interior celular

By LabMedica International staff writers
Posted on 16 Sep 2008
Un microscopio novedoso de rayos X de súper-resolución combina el poder de penetración alta de los rayos X, con la resolución espacial alta, haciendo posible, por primera vez observar la composición detallada del interior de las estructuras celulares y equipos semiconductores.

El instrumento nuevo usa un Megapixel Pilatus (un detector de píxeles de silicona), capaz de contar millones de fotones de rayos X en un área grande. More...
Esta característica clave hace posible registrar patrones de difracción detallados mientras la muestra es escaneada a través del punto focal del rayo. Por el contrario, los microscopios convencionales de barrido de rayos X miden únicamente la intensidad total transmitida.

Los microscopios electrónicos de barrido convencionales pueden suministrar imágenes de alta resolución, pero usualmente solamente para la superficie de la muestra, que debe ser mantenida al vacío. El nuevo microscopio con súper resolución permite que los científicos miren en la profundidad de las muestras biológicas o los semiconductores sin alterarlos. Puede ser usado para caracterizar de manera no destructiva los defectos en nanómetros en los equipos semiconductores enterrados, y ayudar a mejorar la producción y desempeño de equipos semiconductores futuros con características de centésimas de nanómetros.

El poder de penetración de los rayos-x puede ser usado para investigar, células incrustadas o estructuras subcelulares. El método también puede ser transferido a luz electrónica o láser visible, y ayudar en el diseño de microscopios de luz y electrónicos, mejores.

El microscopio fue desarrollado por un equipo de científicos del Instituto Paul Scherrer (PSI; Villigen PSI, Suiza) y la Ecole Polytechnique Fédérale de Lausanne (EPFL; Lausana, Suiza). Los científicos han estado trabajando en conceptos de microscopía de súper-resolución para electrones y rayos-x por muchos años. El profesor de la EPFL y líder del equipo, Franz Pfeiffer, dijo: "Sólo la construcción de un instrumento dedicado de millones de francos suizos en la Fuente de Luz Suiza, en PSI, nos permitió lograr la estabilidad necesaria para implementar nuestro método nuevo en la práctica”.

Enlaces relacionados:
Paul Scherrer Institut
Ecole Polytechnique Fédérale de Lausanne

Platinum Member
Automated Coagulation Analyzer
Hemolumi H6
βeta-Hydroxybutyrate Reagent
β-Hydroxybutyrate LiquiColor®
LAIR2 Antibody Pair Set
LAIR2 Antibody Pair [Biotin]
Gold Member
Electrolyte Analyzer
CBS-4000 (CBS-400)
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Clinical Chemistry

view channel
Image: Study design and workflow (Parankusham H, Vanderlip C, Birkenbihl C, et al. A two-stage plasma biomarker algorithm reduces amyloid PET use and the p-Tau217 gray zone. Annals of Clinical and Translational Neurology. Published online October 19, 2026. doi:10.1002/acn3.70560)

Two-Step Blood Testing Approach Reduces Uncertainty in Amyloid Assessment

Blood-based biomarkers offer a more accessible, less expensive way to detect Alzheimer’s-related brain changes than traditional methods such as amyloid-beta positron emission tomography (Aβ-PET).... Read more

Molecular Diagnostics

view channel
Image: Tumor DNA is extracted from a pathology sample, and normal DNA is extracted from the buffy coat. Both samples undergo WGS to generate the patient-specific mutational signature. At each follow-up, ctDNA extracted from plasma undergoes WGS and is analyzed using a patient-derived signature and an artificial intelligence (AI) pattern recognition algorithm. FFPE: formalin fixed, paraffin embedded. (Snuderl M, Smadbeck J, Wilkins R, et al. The Journal of Molecular Diagnostics, 2026. DOI: 10.1016/j.jmoldx.2026.07.003)

Liquid Biopsy Detects Lung Cancer Recurrence Signals Months Before Imaging

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and remains a major cause of cancer-related death. Early-stage tumors are often treated surgically, but recurrence can still occur... Read more

Immunology

view channel
Image Credit: iStock

Antibody Profiling Predicts Inflammatory Bowel Disease Years Before Diagnosis

Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, involves abnormal immune responses that cause persistent inflammation and damage in the digestive system.... Read more

Pathology

view channel
Image: HETA Quality Control identifies slide quality issues before analysis, while HETA Tumor Detect annotates tumor regions and flags slides likely to contain tumor during scanning. (Photo courtesy of Aignostics)

AI Pathology Platform Targets Workflow Delays and Molecular Test Failures

Pathology laboratories often rely on visual review of tissue slides to assess quality, identify tumors, count mitoses, and estimate tumor content. These tasks can be time-consuming and vary between readers,... Read more

Technology

view channel
Image: Signals LabGistics uses AI to turn natural-language instructions and SOPs into coordinated scientific workflows, helping connect teams, systems, and processes. (Photo courtesy of Revvity)

New AI-Powered System Aims to Streamline Laboratory and Manufacturing Workflows

Scientific laboratories supporting drug development, biotechnology, and materials research increasingly rely on coordinated digital workflows to move data, samples, and activities across teams.... Read more

Industry

view channel
Image: The acquisition of Reveal Genomics would expand Hologic’s oncology diagnostics portfolio to support treatment decisions for more women with breast cancer.

Hologic to Broaden Breast Cancer Testing Portfolio Through Reveal Genomics Acquisition

Hologic (Marlborough, MA, USA) has signed a definitive agreement to acquire Reveal Genomics (Barcelona, Spain), a precision oncology company developing genomic diagnostic tests to help personalize cancer treatment.... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.