We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Gut Microbe Strains Linked to More Severe Strokes

By LabMedica International staff writers
Posted on 09 May 2022
Print article
Image: Gram staining of Negativibacillus massiliensis bacteria isolated from a human left colon sample (Photo courtesy of Aix Marseille University)
Image: Gram staining of Negativibacillus massiliensis bacteria isolated from a human left colon sample (Photo courtesy of Aix Marseille University)

The human microbiome is composed of bacteria, archaea, viruses and eukaryotic microbes that reside in and on individual bodies. These microbes have tremendous potential to impact that physiology, both in health and in disease.

Globally, about 13 million people experience a stroke each year and about 5.5 million people die from strokes. A stroke happens when blood is not able to reach the brain. If blood flow to the brain becomes blocked, oxygen and vital nutrients cannot get to the brain, which can cause brain cells to die.

Medical Scientists at the Sant Pau Research Institute (Barcelona, Spain) and their colleagues have linked specific bacteria in the gut microbiome to both stroke severity and recovery. The team analyzed studied samples from 89 ischemic stroke patients and 12 controls. They performed shotgun metagenomics sequencing to analyze the taxonomic profiles.

The scientists identified multiple types of bacteria associated with an increased risk for ischemic stroke, including the bacteria Fusobacterium and Lactobacillus. They also found the bacteria Negativibacillus and Lentisphaeria were associated with a more severe stroke in the acute phase and the bacteria Acidaminococcus led to poor post-stroke recovery after three months.

Miquel Lledós, PhD, the lead author of the study, said, “Acidaminococcus is an opportunistic pathogen, and this genus has already been related to a higher risk of stroke.” Acidaminococcus is a member of the family Veillonellaceae, known for producing succinate, a compound linked to increased risk factors for cardiovascular disease.”

Dr. Lledós added, “In other pathologies, clinical trials are being carried out in which scientists replace the intestinal flora through dietary changes or fecal transplantation from healthy individuals that is much more consistent in the long term. One way to do that is by using lyophilized compounds of microorganisms in capsules that are easy to ingest and that modify the intestinal flora.”

The authors concluded that multiple new taxonomic profiles associated with stroke, revealing that gut microbiome could be an important factor associated with stroke risk and stroke acute and long-term outcome. The study was presented at the 2022 European Stroke Organisation Conference held May 4-6, 2022 in Lyon, France.

Related Links:
Sant Pau Research Institute 

Gold Supplier
Real-Time Diagnostics Onscreen Viewer
GEMweb Live
Data Management Software
Human Anti-S. Cerevisiae Antibodies Test
Anti-HIV 1/2 ELISA Test
HIV 1/2 Antibody (3rd) Test Kit (ELISA)

Print article
IIR Middle East


Molecular Diagnostics

view channel
Image: Metabolomic profiling reveals risk of multiple diseases all at once (Photo courtesy of BIH)

Single Blood Test Predicts Risk of Multiple Diseases Simultaneously Using AI

Prevention is better than cure. To prevent diseases from occurring in the first place, it is important to identify those individuals who are at particularly high risk as early as possible.... Read more


view channel
Image: OneDraw Blood Collection Device significantly reduces obstacles for drawing blood (Photo courtesy of Drawbridge Health)

Near Pain-Free Blood Collection Technology Enables High-Quality Testing

Blood tests help doctors diagnose diseases and conditions such as cancer, diabetes, anemia, and coronary heart disease, as well as evaluate organ functionality. They can also be used to identify disease... Read more


view channel
Image: The MC-80 digital cell morphology analyzer can screen and diagnose malignant and non-malignant blood diseases (Photo courtesy of Mindray)

Mindray Showcases Hematology Innovations at ISLH 2022

Mindray (Shenzhen, China) showcased its hematology innovations and academic achievements to medical experts from Europe and around the world at the International Symposium on Technological Innovations... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.