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Thermo Fisher Scientific

Clinical Chemistry

Image: Research shows individuals with lower levels of calcium in the blood are more likely to experience SCA than those with higher calcium levels (Photo courtesy of SPL).

Low Serum Calcium Increases Risk of SCA

Sudden cardiac arrest (SCA) is fatal for over 90% of patients, and more than half of men and close to 70% of women who die of SCA have no clinical history of heart disease prior to this cardiac event. It is one of the leading causes of death in the USA and kills more people than any single cancer. More...
19 Oct 2017
Image: The NephroCheck test is intended to assist the clinician in assessing the risk of moderate to severe acute kidney injury within the next 12 hours (Photo courtesy of Astute Medical).

Renal Biomarker Test Prevents Acute Kidney Injury

Acute kidney injury (AKI) is a frequent complication among patients undergoing major surgery, and is known to increase morbidity, mortality risk, and costs. Although the complication can be managed, today’s standard indicators of AKI, such as elevated levels of serum creatinine, may not be present until kidney damage has already occurred. More...
18 Oct 2017
ELITech Group
Image: Immunostaining for nuclear p21 on a pituitary tumor. ACTH-secreting adenoma without cytoplasmic staining (Photo courtesy of the William Harvey Research Institute).

Diagnostic Options When Standard Tests Are Inconclusive

The diagnosis of Cushing’s disease, the predominant endogenous form of Cushing’s syndrome, requires a laboratory strategy that sequentially rules out potential causes of excess cortisol until the correct one is identified. More...
18 Oct 2017
Image: The Synapt G2 high definition mass spectrometer (HDMS) (Photo courtesy of Waters).

Metabolomics Analysis Applied to Investigate MPS

Inborn errors of metabolism (IEM) represent a group of about 500 rare diseases with an overall estimated incidence of 1/2,500. The diversity of involved metabolisms explains the difficulties in establishing their diagnosis. More...
17 Oct 2017
Image: The GEM 4000 whole blood analyzer (Photo courtesy of Werfen UK).

Umbilical Cord Bilirubin Predicts Neonatal Jaundice

Hyperbilirubinemia is one of the commonest causes of admission to hospital in the neonatal period amongst term babies in all settings. Prevention of serious complications depends on effective early treatment, but clinically significant jaundice may not develop until one or more days after delivery. More...
17 Oct 2017
Image: Smell problems can increase people’s risk for health-related conditions and can also be a sign of neurodegenerative disease (Photo courtesy of Getty Images).

Tests for Smell Loss May Detect Alzheimer’s and PD

In a new approach to testing for olfaction dysfunction, researchers have developed “white smells,” mixtures of several odor molecules, which help reduce test bias and patient subjectivity, thus also creating a more globally applicable testing format. They suggest that these tests could also aid in earlier detection of neurological disorders that have been associated with olfaction problems. More...
16 Oct 2017
Image: The FreeStyle Libre Flash Glucose Monitoring System (Photo courtesy of Abbott).

Monitoring System No Longer Requires Fingerstick Calibration

People with diabetes must regularly test and monitor their blood sugar to make sure it is at an appropriate level, which is often done multiple times per day by taking a fingerstick sample and testing it with a blood glucose meter. More...
10 Oct 2017

The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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