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Clinical Chemistry

Image: A new study suggests obesity that affects the liver could play a part in the long-term onset of Alzheimer\'s and dementia (Photo courtesy of Deposit Photos).

Alzheimer’s Disease Risk Impacted by Liver and Diet

Reduced levels of plasmalogens are associated with an increased risk of Alzheimer’s Disease. Plasmalogens are created in the liver and are dispersed through the bloodstream in the form of lipoproteins. More...
21 Aug 2018
Image: The ARCHITECT i2000SR immunoassay analyzer (Photo courtesy Abbott Diagnostics).

Fifth-Generation Cardiac Troponin Assays Compared

Cardiac troponin I (cTnI) and cardiac troponin T (cTnT) are highly specific biomarkers of myocardial injury. The 99th percentile upper reference limit (URL) of a normal reference population is the recommended threshold which defines an increased cTnI or cTnT plasma concentration indicative for myocardial injury. More...
20 Aug 2018
Image: Mannitol salt agar plate with oxacillin showing methicillin-resistant Staphylococcus aureus (Photo courtesy of Medical College, Pondicherry).

Time To Blood Culture Positivity Predicts Infective Endocarditis

Blood cultures are used to detect the presence of bacteria or fungi in the blood, to identify the type present, and to guide treatment. Testing is used to identify a blood infection (septicemia) that can lead to sepsis, a serious and life-threatening complication. More...
16 Aug 2018
Image: Early diagnosis of Parkinson’s disease is important because it affects the choice of therapy and is subject to a relatively high degree of error (Photo courtesy of Technion - Israel Institute of Technology).

Breath Test Detects Early-Stage Parkinson's Disease

Parkinson's disease (PD) is a degenerative disease that destroys brain tissue and affects movement. It has four main symptoms: stiffness, shaking, slowness, and problems with coordination and balance. Other problems can also develop as the disease progresses, including fatigue, speech difficulties, disrupted sleep, memory problems, and depression. More...
15 Aug 2018
Image: A diagram of the causes of diabetes insipidus resulting from the lack of vasopressin (ADH) production in the hypothalamus or the pituitary gland (Photo courtesy of Maria Khatun Mona, RN).

Test Enables Quick Diagnosis for Rare Hormone Disorder

The indirect water-deprivation test is the current reference standard for the diagnosis of diabetes insipidus. However, it is technically cumbersome to administer, and the results are often inaccurate. More...
14 Aug 2018
Image: The G4 Platinum continuous glucose monitoring (CGM) system (Photo courtesy of Dexcom).

Diagnostic Tool Created for Hypoglycemia-Associated Autonomic Failure

Low blood sugar, or hypoglycemia, is a major complication of type 1 and type 2 diabetes. People with diabetes can have difficulty self-administering the exact insulin dose at the correct time to keep blood sugar levels in healthy ranges. More...
14 Aug 2018
Image: One drop of blood is enough for TBIcheck to diagnose a possible mild brain trauma. If a line appears below the control line, the injured person will have to go to the hospital for a CT scan (Photo courtesy of the University of Geneva).

Mild Brain Trauma Diagnosed with POC Device

Every year in Europe, three million people are admitted into hospitals for suspected mild traumatic brain injury (mTBI) cases. Biomarkers have been intensively studied for their potential as diagnostic tools in cases of mTBI to allow accurate diagnosis, improve patient management speeds and reduce medical costs. More...
14 Aug 2018


The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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