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Integrated LC-MS System to Be Released in Conjunction with AACC Annual Meeting

By LabMedica International staff writers
Posted on 01 Aug 2016
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Image: The CLAM-2000 automated LC-MS sample preparation system (Photo courtesy of Shimadzu Scientific Instruments).
Image: The CLAM-2000 automated LC-MS sample preparation system (Photo courtesy of Shimadzu Scientific Instruments).
What may be the first truly integrated sample preparation system for LC-MS (liquid chromatography-mass spectrometry) that allows users to process samples in an instrument that is directly attached to the LC-MS system is to be released at the 2016 AACC Annual Meeting & Clinical Lab Expo (Philadelphia, PA, USA).

Shimadzu Scientific Instruments (Kyoto, Japan) had announced that the release of the Clinical Laboratory Automation Module-2000 (CLAM-2000), a fully integrated sample pretreatment module for LC-MS, will coincide with the 2016 AACC Annual Meeting.

The CLAM-2000 system, which is on display in Booth 4054 of the expo, automatically performs all the processes necessary for analyzing blood and other biological samples, from scanning in information from the blood collection tubes to sample pretreatment and LC-MS analysis. The for-research-use-only instrument is the first truly integrated sample preparation system for LC-MS. It allows users to process samples in an instrument that is directly attached to the LC-MS system, a simple and safe way for lab personnel to process and analyze samples.

The instrument is controlled by a user-friendly interface that offers a variety of functions that regulate reagent management, calibration curve management, control management, and system maintenance management. By automating operations such as dispensing, stirring, filtering, heating, and sample transfer, the system effectively improves data accuracy and achieves the high level of reproducibility needed for clinical research.

“This system highlights the considerable progress made in the use of mass spectrometers for high-sensitivity detection in medical R&D,” said Dr. Scott Kuzdzal, general manager of marketing at Shimadzu Scientific Instruments. “It is ideal for medical research centers, university medical departments, hospital pharmaceutical departments, and contract research organizations that are dealing with issues of variability in analytical results or laboratory efficiency. It can also effectively support forensic applications conducted by universities, research institutes, and testing companies.”

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