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Pathology

Image: HistoCore PEGASUS Plus Tissue Processor (Photo courtesy of Leica Biosystems)

Leica Biosystems Launches HistoCore PEGASUS Plus Dual-Retort Tissue Processor in Europe

Leica Biosystems (Nussloch, Germany) has launched a compact, dual-retort tissue processor, the HistoCore PEGASUS Plus. For the first time, the technology will now be available to medium-sized laboratories, enabling them to optimize histopathology workflows. More...
04 May 2022
Image: MinION sequencing device was used on three novel species for hybrid assembly (Photo courtesy of Oxford Nanopore Technologies)

Urinary Microbiome Linked to Prostate Cancer Risk

Prostate cancer is the most common non-skin malignancy in men in developed countries, with over 250,000 deaths annually worldwide. The clinical course of prostate cancer is highly heterogeneous, and critical decisions are made about the likelihood of aggressive disease based on information obtained at presentation. More...
02 May 2022
Image: Lunit SCOPE PD-L1 (Photo courtesy of Lunit)

Lunit AI-Powered Pathology Solution Aids Highly Accurate Cancer Diagnosis

Programmed death ligand 1 (PD-L1) expression is the standard biomarker in advanced non-small cell lung cancer (NSCLC). However, manual evaluation of PD-L1 tumor proportion score (TPS) by pathologists has practical limitations of interobserver bias, variation in subjectivity on the area of interest, and intensive labor. Now, a new artificial intelligence (AI)-powered TPS analyzer could reduce the human discrepancy. More...
28 Apr 2022
Image: PathScan Enabler IV Histology/Pathology Digital Slide Scanner (Photo courtesy of Meyer Instruments)

Immunohistochemistry-Guided Sequencing Finds Mutations in Most Cortisol-Producing Adenomas

Cushing syndrome (CS) represents a constellation of signs and symptoms associated with chronic and excessive exposure to glucocorticoids, from either endogenous endocrinopathies or, more commonly, from exogenous pharmacologic sources. More...
27 Apr 2022
Image: BOND-MAX Fully Automated IHC and ISH Staining System (Photo courtesy of LeicaBiosystems)

Single-Cell Proteomics of Localized Prostate Cancer Defines Disease Heterogeneity

Prostate cancer affects about 12.6% of men over the course of their lives, and while most individuals with localized disease can be cured, disease does recur in a small number of patients. The treatment of localized prostate cancer is based on clinicopathological information including Gleason score, prostate-specific antigen (PSA) levels, stage, and patient age. More...
26 Apr 2022
Image: Micrograph of brain tissue with glioma enlargement and disease histology (Photo courtesy of 123rf.com)

Two Simple Serum Biomarkers Differentiate Lymphoma from Glioma

Two simple serum biomarkers, absolute lymphocyte count and prognostic nutritional index, which are easily derived from routine pre-treatment blood tests, have fair correlation and acceptable diagnostic accuracy for differentiating primary central nervous system lymphoma (PCNSL) from high-grade glioma (HGG) in patients with similar morphology on MRI. More...
22 Apr 2022
Image: Testing Neurofilament Light (NF-L) chain in blood samples to monitor neurodegenerative diseases: qualification of an ultrasensitive immuno-assay using clinical serum and plasma samples (Photo courtesy of Advanced BioScience Laboratories, Inc)

Neurofilament Light Biomarker Linked With Parkinson's Disease

Parkinson's disease is caused by a loss of nerve cells in part of the brain called the substantia nigra. This leads to a reduction in a chemical called dopamine in the brain. Blood biomarkers may allow earlier identification of Parkinson’s disease (PD), Parkinsonism, and poor PD-related outcomes, such as physical functioning. More...
19 Apr 2022
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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