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Molecular Diagnostics

Image: Bone marrow aspirate from a patient with diffuse large B-cell lymphoma (Photo courtesy of Dr. Peter G. Maslak, MD)

Targeted Locus Amplification Validated for Lymphoma

Structural variation (SV) in the genome is a recurring hallmark of cancer. Translocations (genomic rearrangements between chromosomes) in particular are found as recurrent drivers in many types of hematolymphoid malignancies. More...
15 Jul 2021
Image: The Super Sensitive 1-STEP Polymer HRP IHC detection kit (Photo courtesy of BioGenix)

Protein Biomarker Helps Diagnose Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC), characterized by dense desmoplastic stroma laid down by pancreatic stellate cells (PSC), has no reliable diagnostic biomarkers for timely detection. More...
14 Jul 2021
Image: The ProSpecT Rotavirus Microplate ELISA Assay (Photo courtesy of Thermo Fisher Scientific)

Rotavirus Co-Infection with Diarrheagenic Pathogens Detected by Different Methods

Diarrhea is the second most common cause of childhood mortality worldwide, with Group A Rotavirus (RVA) recognized as a leading diarrheagenic agent, causing 38% of acute diarrhea among children aged five and below worldwide. More...
14 Jul 2021
Image: (c) Illustration of workflow for human buccal swab sample testing on the toroidal PCR. Total turnaround time is under one hour. (d) Genotyping 15 SNP loci from buccal swab samples from a family trio (Photo courtesy of Rice University)

Portable, PCR-Based Assay Developed for Rapid, Multiplexed DNA Detection

The detection of specific DNA sequences is central to precision medicine, from pathogen identification to the risk assessment of human genetic diseases to disease prognosis. While technologies exist for DNA detection, they tend to be limited either in terms of multiplexing, turnaround times, quantification accuracy, or specificity for single-nucleotide differences. More...
13 Jul 2021
Image: A normal bone marrow biopsy: Note the presence of an eosinophilic myelocyte, a basophilic myelocyte, and a plasma cell. There is an association between a common, benign genotype and unnecessary bone marrow biopsies among African-American patients (Photo courtesy of University of Utah School of Medicine)

Genotyping Helps Avoid Needless Bone Marrow Biopsies in African-Americans

Bone marrow biopsies may be used unnecessarily in some African American individuals who are genetically predisposed to having relatively low white blood cell counts. More...
13 Jul 2021
Image: Artist’s depiction of stress molecules in blood being detected electronically inside nanowells (Photo courtesy of Ella Marushchenko)

A Novel Nanowell Array Sensor for POC Measurement of Stress Hormones

Researchers have constructed a microchip "nanosensor" to measure stress hormones such as cortisol in a dedicated nanowell array, which does not require molecular labels or washing steps. More...
13 Jul 2021
Image: Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease (Photo courtesy of Wikimedia Commons)

Novel Stool Biomarker Screening Tests Detect Colorectal Cancer and Inflammatory Bowel Disease

Two recent papers described the use of novel stool protein biomarkers in screening tests to diagnose colorectal cancer (CRC) and inflammatory bowel disease (IBD). More...
12 Jul 2021
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Antipsychotic TDM Assays
Saladax Antipsychotic Assays
POC Helicobacter Pylori Test Kit
Hepy Urease Test
Capillary Blood Collection Tube
IMPROMINI M3
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Ketosis and DKA Test
D-3-Hydroxybutyrate (Ranbut) Assay


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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