We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




Gene-Based Molecular Diagnostic Prostate Cancer Test Validated

By LabMedica International staff writers
Posted on 27 Oct 2008
A new gene-based molecular diagnostic test for prostate cancer has been validated and is ready to be commercialized for use by physicians on their patients at risk of having prostate cancer.

The combined results of recently completed double-blinded clinical validation studies demonstrated that the new gene-based molecular diagnostic test for prostate cancer achieved a sensitivity of 90% for correctly identifying the presence of Grade 3 or higher prostate cancer cells, and a specificity of 97% for correctly identifying non-cancer cells (normal and benign prostatic hyperplasia), representing an overall test accuracy of 93%. More...


The test was developed by the Health Discovery Corporation (HDC; Savannah, GA, USA) and it will be performed at Clarient's Clinical Laboratory (Aliso Viejo, CA, USA). HDC will receive 30% royalty on each test performed. The genomics based-test should be performed on the 75% of men (approximately 600,000 men annually in the US alone) with initial biopsies reported as negative, to assist physicians in identifying those men who could have prostate cancer that was missed by the first biopsy.

Stephen D. Barnhill, M.D., chairman and CEO of HDC commented, ``The successful development, validation and commercialization of this new molecular diagnostic test for prostate cancer proves that HDC, by combining our patented [support vector machine] SVM and [support vector machine-recursive feature elimination] SVM-RFE technology and our expert scientific team, has the ability to produce new molecular diagnostic and prognostic tests, which are the future of personalized medicine. Our patent protected discovery method allows us to develop molecular diagnostic and prognostic tests that are free of outside intellectual property rights and thereby allows HDC to fully patent protect our molecular diagnostic gene signatures. Using the same expertise of our scientific team and the HDC patented technology, we are currently developing additional new molecular diagnostic tests in a variety of other cancers.”

Related Links:
Health Discovery Corporation
Clarient's Clinical Laboratory



New
Gold Member
Collection and Transport System
PurSafe Plus®
Collection and Transport System
PurSafe Plus®
New
Gold Member
Automatic Chemiluminescence Immunoassay Analyzer
Shine i2000
Anterior Nasal Specimen Collection Swabs
53-1195-TFS, 53-0100-TFS, 53-0101-TFS, 53-4582-TFS
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Hematology

view channel
Image: New evidence shows viscoelastic testing can improve assessment of blood clotting during postpartum hemorrhage (Photo courtesy of 123RF)

Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage

Postpartum hemorrhage, severe bleeding after childbirth, remains one of the leading causes of maternal mortality worldwide, yet many of these deaths are preventable. Standard care can be hindered by delays... Read more

Immunology

view channel
Image: The CloneSeq-SV approach can allow researchers to study how cells within high-grade serous ovarian cancer change over time (Photo courtesy of MSK)

Blood Test Tracks Treatment Resistance in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is often diagnosed at an advanced stage because it spreads microscopically throughout the abdomen, and although initial surgery and chemotherapy can work, most... Read more

Industry

view channel
Image: The collaboration aims to improve access to Hb variant testing with the Gazelle POC diagnostic platform (Photo courtesy of Hemex Health)

Terumo BCT and Hemex Health Collaborate to Improve Access to Testing for Hemoglobin Disorders

Millions of people worldwide living with sickle cell disease and other hemoglobin disorders experience delayed diagnosis and limited access to effective care, particularly in regions where testing is scarce.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.