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Technology

Image: A diagram of simplifying disease diagnosis using topically applied nanotechnology could change the way skin diseases such as abnormal scars are diagnosed and managed (Photo courtesy of Nanyang Technological University).

Topical Nanotechnology Simplifies Skin Disease Diagnosis

Tissue biopsies are necessary for the accurate diagnosis of skin diseases, but their application is limited by the pain, inconvenience, and morbidity experienced by patients, as well as risks of scarring and infection. More...
30 May 2018
Image: A laboratory setup used to test exosomes extracted from blood samples for pancreatic cancer biomarkers (Photo courtesy of the University of California, San Diego).

Electronic Chip Captures Pancreatic Cancer Exosomes for Analysis

A novel electronic chip-based method for rapid capture and analysis of exosomes together with their protein and other biomarker content will facilitate liquid biopsy diagnosis of pancreatic cancer. More...
29 May 2018
Image: The RainDrop digital PCR system (Photo courtesy of RainDance Technologies).

Factors Affecting Plasma DNA Analysis Evaluated

There is vast potential in precision-medicine methods of both detecting and monitoring disease by looking for indications of cancer mutations in cell-free DNA (cfDNA), circulating in the blood. However, there are many factors that can significantly alter these samples as they are collected and analyzed. More...
21 May 2018
Image: The Genedrive HCV ID kit is a qualitative assay providing results in 90 minutes in a decentralized environment (Photo courtesy of Genedrive).

Near-Patient Hepatitis C Assay Validated

Chronic infection with hepatitis C virus (HCV) is a major public health problem, estimated to infect 1.0% of the world’s population (71 million people) and to be responsible for 400, 000 annual deaths as a result of cirrhosis and liver cancer. More...
17 May 2018
Image: The C1000 Touch thermal cycler (Photo courtesy of Bio-Rad).

Assays Using ddPCR Quantify DNA Fragments

Optimized droplet digital polymerase chain reaction (ddPCR) assays have been developed that quantify short and long DNA fragments. These assays have been used to analyze plasma cell-free (cfDNA) fragment size distribution in human blood. More...
14 May 2018
Image: A microscopic appearance of cell blocks prepared by the HistoGel + ethanol (EtOH) method versus HistoGel-only and the EtOH-only methods. The insets in C and F illustrate excellent cytomorphologic preservation with this method (Photo courtesy of Memorial Sloan Kettering Cancer Center).

Cell Block Prep Method Modified for Molecular Studies

Biomarker testing is currently required to guide the selection of a growing number of targeted therapies in patients with a wide range of malignancies. Combined with increasing use of immunostaining for tumor diagnosis, this has substantially increased the demand for the amount of tissue in small specimens. More...
14 May 2018
Image: The low-cost, portable laboratory on a phone that can interpret results from a microplate assay (Photo courtesy of Washington State University).

Smart Phone Reader Detects Common Pathogens

In rural or low resource areas, doctors sometimes must rely on a patient's symptoms or use their own judgement in looking at test sample color results to determine whether a patient has an infection. More...
10 May 2018
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LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.
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