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Technology

Image: The positive results of Helicobacter pylori infection by the traditional Giemsa stain. White arrows indicate stained Helicobacter pylori (blue) that are attached to the brush border of the gastric foveolar epithelial cells (Photo courtesy of National Health Research Institutes).

Giemsa Stain Outperforms Urease Test for Helicobacter Pylori Diagnosis

More than 50% of the worldwide population is infected by Helicobacter pylori which is harbored in their upper gastrointestinal tract. Despite having chronic gastritis, most people infected by H. pylori are asymptomatic and have no specific clinical signs and symptoms. More...
05 May 2020
Image: Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging (Photo courtesy of Massachusetts General Hospital Research Institute).

Ultra-Fast Cycling for Multiplexed Cellular Fluorescence Imaging

In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. Until now, analyses of these dynamic changes with conventional biopsies and tissue sections could take days to weeks, or not occur at all prior to treatment. More...
07 Apr 2020
Image: The SpectraMax M5 Microplate Reader is the standard for UV/visible multi-mode reader absorbance, providing ultrafast, full spectral range detection for cuvettes, 96-, and 384-well microplates (Photo courtesy of Molecular Devices).

Novel Rapid Test Developed for Detecting Carbapenemase

As a potent β-lactamase, carbapenemase can degrade almost all β-lactam antimicrobial drugs, including the carbapenems, regarded as the last line of therapy for many life-threatening infections. If uncontrolled, the spread of these carbapenemases is expected to increase therapeutic failure and leave many patients with no effective treatment options. More...
02 Apr 2020
Image: The high throughput immunochemistry cobas e 801 module (Photo courtesy of Roche Diagnostics).

Novel Method Developed to Estimate LDL Particle Size

Premature atherosclerotic disease commonly occurs in individuals with atherogenic dyslipidemia who share a phenotype characterized by centripetal obesity, insulin resistance, and physical inactivity. Cardiovascular diseases (CVD) are the leading cause of mortality in the Western World being subclinical atherosclerosis the triggering factor for most of these events. More...
01 Apr 2020
Image: A new fluid analyzing platform allows for the isolation of circulating tumor cells (CTCs), which are formed during metastasis (Photo courtesy of NYU Abu Dhabi)

Hybrid Liquid Biopsy Platform Enables Tracking and Monitoring of Circulating Tumor Cells

By creating a hybrid microfluidic liquid biopsy platform that incorporates atomic force microscopy (AFM), cancer researchers have captured and characterized circulating tumor cells (CTCs), a technique which should prove useful in the diagnosis and prognosis of prostate cancer as well as other forms of cancer. More...
01 Apr 2020
Image: The image shows bacterial cells trapped in a three-dimensional microbead matrix (Photo courtesy of Wenrong He, Rochester Institute of Technology)

Novel Nanofluidic Device Traps and Concentrates Pathogenic Bacteria

 A nanofluidic device containing stacked magnetic beads of different sizes has been developed to efficiently trap, concentrate, and retrieve Escherichia coli (E. coli) bacteria from liquid suspensions. More...
31 Mar 2020
Image: The fully automated Idylla EGFR Mutation Test covers 51 mutations in exons 18–21 in a single cartridge using only one FFPE tissue section from metastatic non-small cell lung cancer (NSCLC) showing a high concordance of >95% compared with reference methods (Photo courtesy of Biocartis).

EGFR Mutation Assay Cartridges Evaluated

 Lung cancer remains the leading cause of cancer deaths. The management of lung cancer has been aided by the better understanding of molecular mechanisms involved in its initiation and progression and increased usage of molecular testing. More...
24 Mar 2020
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