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Technology

Image: A CyteFinder instrument is an automated six channel fluorescence microscopes that rapidly image slides and employ machine learning to identify rare cells (Photo courtesy of RareCyte)

Circulating Trophoblast-Based Noninvasive Prenatal Testing Are Feasible

 Circulating cells from the fetus or placenta in a pregnant woman’s blood, primarily trophoblasts and nucleated fetal red blood cells (fnRBCs), have long been appreciated as potential targets for noninvasive prenatal testing (NIPT) and diagnosis. More...
26 Dec 2019
Image: Acoustofluidic exosome isolation chip for salivary exosome isolation. The microfluidic channel is shown by red dye solution and the coin demonstrates the size of the chip. Two pairs of gold interdigital transducers are deposited along the channel, which separates particles according to size (Photo courtesy of The Journal of Molecular Diagnostics)

A Rapid Method for Isolating Viral DNA-enriched Salivary Exosomes for Diagnosis and Monitoring of Oropharyngeal Cancer

 A novel method, based on the combination of microfluidics and acoustics, for concentrating exosomes containing viral DNA from the saliva of oropharyngeal cancer patients was found to be 15 times more sensitive than the current gold standard differential centrifugation method. More...
24 Dec 2019
Image: The Fuji dri-chem immuno AG cartridge FluAB kit (Photo courtesy of Fujifilm Corporation)

High Performance of Rapid Influenza Diagnostic Test Validated

 Influenza is a leading infectious cause of morbidity and mortality worldwide. Annually, about 5% to 10% of adults and 20% to 30% of children have symptoms of influenza-like illness (ILI), and approximately 650,000 deaths secondary to influenza occur each epidemic season. More...
19 Dec 2019
Image: Norovirus, which is highly contagious and can survive for days on hard surfaces, infects as many as 700 million people globally every year. PCR.ai is a highly accurate time-saving tool that reduces complexity of qPCR analysis for this and other pathogens (Photo courtesy of Centre for Infection/Public Health England/SP).

Implement Diagnostics System Improves Infectious Disease Testing

 A team of scientists recently began using machine-learning tools and assessed them in a prospective clinical trial to determine whether artificial intelligence could perform better than specialists in clinical test interpretation. More...
17 Dec 2019
Image: The Aptima BV and Aptima CV/TV assays for the diagnosis of infectious vaginitis (Photo courtesy of Hologic).

Vaginitis Tests Offer Improvements Over Gold Standard Methods

 Gynecologist visits in the USA are motivated by an inflammation of the vagina called vaginitis. Infectious vaginitis due to bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and Trichomonas vaginalis accounts for a significant proportion of all gynecologic visits in the USA. More...
16 Dec 2019
Image: Micrograph showing a prostate cancer (conventional adenocarcinoma) with perineural invasion (Photo courtesy of Wikimedia Commons)

Home Urine Collection for More Accurate Prostate Cancer Detection

 A standardized sampling system enables men being tested for prostate cancer to collect a urine sample at home and mail it to a laboratory for analysis. More...
09 Dec 2019
Image: Methods of extracting features from label-free immune cell analysis. Multivariate label-free data, composed of both morphological and spectral parameters, are used to identify high-level features at the single-cell level such as cellular type, response to drugs, as well as response differences between specimens (Photo courtesy of Osaka University)

Non-Invasive Microscopy Detects Activation and Distinguishes Cell Types

 Measurement techniques that allow the global analysis of cellular responses while retaining single-cell sensitivity are increasingly needed in order to understand complex and dynamic biological processes. More...
04 Dec 2019
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LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.
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