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Image: DBS sampling is simple, inexpensive and can be self-collected by the patient at home, using a simple finger prick (Photo courtesy of University of Birmingham)

Use of Dried Blood Samples Facilitates Tracking of COVID-19 Antibodies

A recent study confirmed that dried blood spot samples could be used as an alternative to venous blood for detecting antibodies to the SARS-CoV-2 virus (COVID-19). More...
13 Oct 2020
Image: Cryptosporidium oocysts and the larger Giardia cysts stained by Crypto/Giardia IFA kit (Photo courtesy of Cellabs).

Smartphone Microscopic Method Detects Cryptosporidium and Giardia

Food and water-borne illness arising from the consumption of contaminated food and water are serious health hazards globally. Cryptosporidium and Giardia are the major food and water‒borne parasites. The infection occurs mainly by (oo)cyst phase of the parasites. More...
30 Sep 2020
Image: Laboratory set-up of microfluidic sorting and purification of cells during red blood cell culture and manufacturing (Photo courtesy of Singapore-MIT Alliance for Research and Technology).

Microfluidic Label-Free Bioprocessing of Reticulocytes from Erythroid Culture

Blood transfusions save millions of lives every year, but over half the world's countries do not have sufficient blood supply to meet their needs. The ability to manufacture red blood cells (RBCs) on demand, especially the universal donor blood (O+), would significantly benefit those in need of transfusion. More...
30 Sep 2020
Image: Illustration demonstrating painless and biodegradable microneedles on a paper patch (Photo courtesy of University of Tokyo)

Paper-Based Microneedle Skin Patch for Continuous Glucose Monitoring

A microneedle skin patch for the continuous monitoring of an individual’s glucose level was designed to be a painless and disposable screening and diagnostic test for diabetes patients, as well as those with pre-diabetes. More...
23 Sep 2020
Image: The Aedes aegypti mosquito can spread various tropical diseases including dengue, zika, and chikungunya, which have similar symptoms (Photo courtesy of Gwangju Institute of Science and Technology)

A Paper-Based Nucleic Acid Testing Device for Rapid Diagnosis of Mosquito-Borne Viral Diseases

An all-in-one nucleic acid testing device loaded into a paper chip forms the basis for a simple, rapid diagnostic test for a range of mosquito-borne viral diseases. More...
22 Sep 2020
Image: The QX200 droplet digital polymerase chain reaction (ddPCR) instrument (Photo courtesy of Bio-Rad).

Click Chip’ Detects Early-Stage Liver Cancer Biomarkers in Extracellular Vesicles

 Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related deaths worldwide. The poor prognosis of HCC can be attributed to the fact that diagnosis is often made at a late stage in disease development. More...
21 Sep 2020
Image: Upconverting nanoparticles: With the combination of NIR-excitation (980 nanometers) and detection at a lower wavelength, the autofluorescence from biological samples is totally eliminated, and the particles are detectable through tissue sections and even in whole blood (Photo courtesy of Kaivogen Oy)

Novel Rapid Lateral Flow Assay Measures Ovarian Cancer Biomarker CA125

A radically modified lateral flow immunoassay was able to detect the ovarian cancer biomarker glycosylated CA125 in serum samples and rapidly differentiate epithelial ovarian cancer from benign endometriosis and healthy controls. More...
21 Sep 2020
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