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Immunology

Image: Schematic diagram of the IMMray PanCan-d assay that relies on the IMMray microarray technology, where single chain fragment antibodies are printed onto a slide in a measured amount as a microarray of different antibody biomarkers (Photo courtesy of Immunovia)

Immunoassay Detects Pancreatic Cancer in People at High Risk

An immunoassay was able to detect pancreatic cancer in high-risk individuals and with high sensitivity and specificity. More...
28 Feb 2022
Image: The ABI PRISM 3100 Genetic Analyzers is an automated capillary electrophoresis systems that can separate, detect, and analyze fluorescent-labeled DNA fragments in one run (Photo courtesy of Michaela Pereckas)

Chromosomally Normal Miscarriage Is Associated With Vaginal Dysbiosis

Emerging evidence supports an association between vaginal microbiota composition and risk of miscarriage; however, the underlying mechanisms are poorly understood. We aim to investigate the vaginal microbial composition and the local immune response in chromosomally normal and abnormal miscarriages and compare this to uncomplicated pregnancies delivering at term. More...
17 Feb 2022
Illustration

Novel Immune-Profiling Method Reports Specific Immune Cell Types Using Only DNA from Blood

A novel immune-profiling method can return detailed immune cell type proportions using only DNA from blood with no requirement for intact cells, potentially allowing for individualized prediction of outcomes in immunotherapy patients. More...
10 Feb 2022
Image: Heart rate variability changes with levels of inflammatory serum markers. Left: normal levels of IL-12 and ICAM-1 associated with normal heart rate variability. Right: increased levels of IL-12 and ICAM-1 resulting in decreased heart rate variability. IL-12 is known to associate with arterial stiffness in healthy (Photo courtesy of BMC)

Elevated Interleukin-12/23p40 Indicates Dysfunctional Heart Rate Variability in T2D

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in type 2 diabetes (T2D), accounting for approximately 50% of all deaths. Cardiovascular functions, including heart rate, heart contractility, and blood pressure, are regulated by autonomic sympathovagal balance. More...
08 Feb 2022
Image: Schematic diagram of image-enabled cell sorting, developed at BD Biosciences and tested by European Molecular Biology Laboratory (Photo courtesy of BD Bioscience)

High-Speed Fluorescence Image-Enabled Cell Sorting Tested

Cell sorting through flow cytometry is a technique that enables scientists to identify and sort individual cells based on specific characteristics of each cell in order to study them in more detail, evaluate how each cell may react to a new drug or perform other single cell studies. More...
03 Feb 2022
Image: The MACSQuant Analyzer 16 is engineered to expand the horizons of automated data acquisition with 16 optical parameters (Photo courtesy of Miltenyi Biotec)

ABO Blood Group Related to Specific Immune Response to Anti-SARS-CoV-2

Markers of the protective humoral response, such as total anti-SARS-CoV-2 immunoglobulins and neutralizing antibodies, have been observed to decrease in convalescent individuals, even though a potential long-lasting humoral B-cell memory subset was detected. More...
31 Jan 2022
Image: The High Capacity RNA-to-cDNA Kit is a streamlined reverse transcription kit designed for optimum performance with TaqMan Gene Expression Master Mix, Power SYBR Green PCR Master Mix, and other PCR enzymes (Photo courtesy of Thermo Fisher Scientific)

Melanoma Test Offers Reassurance of Low Risk of Cancer Spread

Cutaneous melanoma is an aggressive form of skin cancer with an increasing worldwide incidence, particularly in the younger population. Although treatment for patients with metastatic melanoma has improved remarkably in the last decade, principally with targeted therapies and immune checkpoint modulators, there are still no consistently beneficial treatments for patients with metastatic disease. More...
25 Jan 2022
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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