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Eurofins Technologies

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Ground-Breaking Test Assesses Expansion and Persistence of CAR-T Therapy in Cancer Patients

By LabMedica International staff writers
Posted on 21 Feb 2023
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Image: ExPeCT CAR-T multiplexed qPCR) assay directly monitors effectiveness of CAR T-cell therapy (Photo courtesy of Eurofins Viracor)
Image: ExPeCT CAR-T multiplexed qPCR) assay directly monitors effectiveness of CAR T-cell therapy (Photo courtesy of Eurofins Viracor)

Chimeric Antigen Receptor T-Cell (CAR-T) therapy is a revolutionary form of immunotherapy that utilizes genetically engineered T-cells to attack cancer cells and has demonstrated promise in treating various types of cancers. Research has shown that the persistence and expansion of CAR-T therapy are important indicators of how long the therapy can remain effective in the patient. Now, a ground-breaking test provides clinicians with an accurate and comprehensive assessment of the CAR-T cell population in the patient's body and offers insights to therapy effectiveness.

Eurofins Viracor LLC (Lenexa, KS, USA) has launched the ExPeCT CAR-T multiplexed quantitative real-time PCR (qPCR) assay that acts as a powerful diagnostic tool to monitor and optimize CAR-T therapy involving patients with pre-B cell acute lymphoblastic leukemia and B cell lymphomas. The test, based on a method developed by Eurofins Viracor, is designed to help clinicians better understand how CAR-T therapy is performing for their patients. The test marks an important step forward in the evaluation and management of CAR-T therapy in cancer patients by helping clinicians to make more informed decisions about the best course of treatment for their patients.

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