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Hematology

Image: Genetron has received CE Mark for its human B lymphocyte minimal residual disease detection kit (Photo courtesy of Genetron Health)

NGS Technology-Based Assay Detects Minimal Residual Disease in Patients with Lymphatic Hematological Tumors

A new assay based on high-throughput next generation sequencing (NGS) technology can test the CDR3 regional sequence of the IgH/K/L gene of the B cell receptor (BCR) in bone marrow samples collected from patients with B lymphpocytic leukemia (B-ALL/CLL) and multiple myeloma (MM) before and after the treatment. More...
20 Apr 2022
Image Technozym vWF:Ag ELISA is an assay kit for determination of von Willebrand Factor (vWF) antigen in plasma and concentrates (Photo courtesy of Diapharma)

Non-O Blood Type Cancer Patients Face Higher Risk of Developing Thrombosis

Venous thromboembolism includes deep-vein thrombosis (DVT), a blood clot that typically forms in the deep veins of the leg, and pulmonary embolism (PE), a life-threatening condition that occurs when a blood clot breaks free and becomes lodged in the arteries of the lung. More...
19 Apr 2022
Image: Fluidigm CyTOF2 Mass Cytometer (Photo courtesy of University of Minnesota)

Epigenomic Biomarker Predict CAR T-Cell Therapy Resistance in Pediatric Leukemia

Children with acute lymphoblastic leukemia (ALL) whose cells express an epigenomic biomarker rooted in DNA methylation patterns may be less likely to respond to CD19-directed CAR T-cell therapy. More...
18 Apr 2022
Image: POC device could monitor blood ammonia in liver disease patients (Photo courtesy of Versantis)

Portable Point-of-Care (POC) Device to Monitor Blood Ammonia in Liver Disease Patients

Versantis AG (Zurich, Switzerland) is developing a prototype POC device named TS-01 based on the polymersome-based ammonia quantification method. TS-01 is a unique point-of-care diagnostic device for at-home measurement of ammonia in blood, the primary cause of hepatic encephalopathy (HE). More...
15 Apr 2022
Image: Umbilical cord blood has increased access to potentially curative therapy for patients with life-threatening disorders of the bone marrow and immune system (Photo courtesy of Cellsafe Biotech Group)

Primary Graft Failure Identified by Early Chimerism Following DCBU Transplantation

Umbilical cord blood transplantation (UCBT) has increased access to potentially curative therapy for patients with life-threatening disorders of the bone marrow and immune system. The introduction of reduced intensity conditioning (RIC) regimens and double umbilical cord unit infusions (DUCBT) has broadened the applicability of UCBT to frailer or larger recipients. More...
14 Apr 2022
Image: New data shows blood test highly accurate in detecting multiple cancers (Photo courtesy of Guardant Health)

Blood Test Proves Highly Accurate in Detecting Multiple Cancers in Early Stage

Guardant Health, Inc. (Redwood City, CA, USA) has announced new data demonstrating the ability of the company’s investigational next-generation Guardant SHIELD multi-cancer assay to accurately detect early-stage cancers. More...
13 Apr 2022
Image: LeukoPrint is a first-in-class leukemia sWGS CNA test (Photo courtesy of SeekIn Inc.)

First-of-Its-Kind Molecular Karyotyping Test Assists Hematologists in Diagnosing Leukemia

A new test kit can evaluate copy number aberrations (CNAs) in bone marrow cells and/or circulating cell-free DNA (cfDNA) via shallow whole-genome sequencing (sWGS), in combination with conventional cytogenetics technologies, to make leukemia diagnosis, molecular subtyping, prognostic stratification and treatment response monitoring more precise and comprehensive. More...
11 Apr 2022
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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