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BioResearch

Image: A ball-and-stick model of the docosahexaenoic acid (DHA) molecule. DHA is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina (Photo courtesy of Wikimedia Commons).

Synthetic Fatty Acid Derivatives Display Anti-Cancer Potential

Metabolites produced during digestion of omega-3 fatty acids have been found to have anti-cancer properties, and their synthetic derivatives have the potential to be developed into potent chemotherapeutic drugs. More...
26 Jul 2018
Image: A model of human calpastatin (Photo courtesy of Sigma-Aldrich).

Protein Combination Reduces Muscle Damage in ALS Model

Researchers have found that high levels of the enzyme mitofusion 2 (Mfn2) prevent nerve degeneration, muscle atrophy, and paralysis in a mouse model of the muscle wasting disease amyloid lateral sclerosis (ALS). More...
25 Jul 2018
Image: When the enzyme DYRK3 is inhibited, mitotic defects are resulting (red: droplets, green: spindle, blue: DNA) (Photo courtesy of Arpan Rai, University of Zurich).

Mechanism Regulates Organelle Distribution during Cell Division

A team of Swiss cell biologists has discovered how cells maintain the integrity and distribution of cytoplasmic organelles during and following the process of cell division. More...
24 Jul 2018
Image: The eye of a zebrafish embryo deficient in NADPH oxidase 2 has an enlarged ganglion cell layer (green) and altered innervation of the brain, which leads to problems with signaling between the eyes and the brain (Photo courtesy of Dr. Daniel Suter, Purdue University).

Model Defines Role of Reactive Oxygen Species in Neural System Development

Using a mutant zebrafish model, a team researching development of the neural system has found a molecular mechanism linking reactive oxygen species to growth of the retina and its associated nerves. More...
23 Jul 2018
Image: A micrograph of a teratoma showing tissue from all three germ layers: mesoderm (immature cartilage - left-upper), endoderm (gastrointestinal glands - center-bottom) and ectoderm (epidermis - right) (Photo courtesy of Wikimedia Commons).

Teratomas Offer Source for Rebuilding Damaged Tissues

Muscle stem cells, which were derived from benign teratoma tumors, were found to demonstrate exceptional potential as starting material for rebuilding and maintaining damaged muscle tissues. More...
19 Jul 2018
Image: This photomicrograph reveals the histopathology in an acute case of gonococcal urethritis using Gram-stain technique. This slide demonstrates the non-random distribution of gonococci among polymorphonuclear neutrophils. Note that there are both intracellular and extracellular bacteria in the field of view (Photo courtesy of the CDC).

Novel Bacterial Inhibitor Blocks Lysozyme Activity in Model

A team of molecular microbiologists has identified a mechanism by which certain bacteria – in particular the Gram-negative pathogen Neisseria gonorrhoeae – avoid lysozyme destruction. More...
18 Jul 2018
Image: A histopathology of urothelial carcinoma of the urinary bladder (Photo courtesy of Wikimedia Commons).

MicroRNA Biomarker Identified for Bladder Cancers

Cancer researchers have identified a microRNA that acts as a prognostic biomarker of p53-like bladder cancers. More...
17 Jul 2018
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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