We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us


Curetis GmbH develops and commercializes molecular diagnostic products that are designed to address the global challe... read more Featured Products: More products

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Rapid Molecular Diagnostics Platform Uses Multiplex PCR Technology for Fast Diagnosis of Severe Infectious Diseases

By LabMedica International staff writers
Posted on 20 Apr 2023
Print article
Image: The Unyvero A50 System can process two cartridges independently with full random-access capabilities (Photo courtesy of Curetis)
Image: The Unyvero A50 System can process two cartridges independently with full random-access capabilities (Photo courtesy of Curetis)

In order to improve patient outcomes in cases of bacterial co-infections like severe pneumonia, rapid detection of pathogens and associated resistance markers is crucial to guide appropriate antibiotic treatment. Now, a cutting-edge molecular diagnostic platform can reliably and accurately diagnose severe infectious diseases by using multiplex PCR technology to detect a wide range of microorganisms, antibiotic resistance markers, or toxins from sample-to-answer within 4-5 hours.

Curetis GmbH’s (Holzgerlingen, Germany) Unyvero A50 system is designed to support various applications for diagnosing severe infectious diseases through syndromic testing. The Unyvero A50 system offers five panels to test for Hospitalized Pneumonia (HPN), Blood Stream Infections (BCU), Implant & Tissue Infections (ITI), Intra-Abdominal Infections (IAI), and Urinary Tract Infections (UTI). Unyvero's multiplex diagnostic panels employ a molecular approach using multiplex PCR technology to detect a wide range of clinically relevant microorganisms and antibiotic resistance markers. This allows for the rapid and accurate identification of infectious agents within less than five hours. The ability to concurrently detect various clinically relevant microorganisms and antibiotic resistance in a single test facilitates prompt identification of likely pathogens and more rapid, targeted antibiotic selection.

The Unyvero multiplex diagnostic panels include the Unyvero Hospitalized Pneumonia (HPN) Cartridge, which tests for 38 reportable targets (21 pathogens and 17 resistance genes) within 4-5 hours, enabling targeted syndromic treatment during the critical early hours of infection. The Unyvero panel range also features the Unyvero Implant & Tissue Infection (ITI) Cartridge, which tests for 46 reportable targets (29 pathogens and 17 resistance genes) and delivers results with high sensitivity and specificity within 4-5 hours. This test panel allows physicians to swiftly diagnose infections and determine the most effective treatment.

Additionally, the Unyvero multiplex diagnostic panels include the Unyvero Blood Culture (BCU) Cartridge for positive blood cultures, testing for 50 reportable targets (34 pathogens and 16 resistance genes) with a single sample, delivering results with high sensitivity and specificity within 4-5 hours. Additionally, the panels range features the Unyvero Intra-Abdominal Infection (IAI) Cartridge, which tests for 50 targets (26 pathogens, 2 toxins, and 22 resistance genes) with a 4-5 hour sample-to-answer time. Based on this comprehensive analysis, physicians can promptly decide on the most suitable treatment path, resulting in improved outcomes, reduced hospital stays, and decreased healthcare costs.

Related Links:
Curetis GmbH

Flocked Swab
HydraFlock and PurFlock Ultra
Gold Supplier
Foam Tipped Applicator
PurSwab 5"
Rapid Test Analyzer
RapiRead CUBE Reader
Auto Immunochemistry System

Print article


Clinical Chem.

view channel
Image: Electrochemical cells etched by laser on wooden tongue depressor measure glucose and nitrite in saliva (Photo courtesy of Analytical Chemistry)

Biosensor-Fabricated Wooden Tongue Depressor Measures Glucose and Nitrite in Saliva

Physicians often use tongue depressors to examine a patient's mouth and throat. However, it is hard to imagine that this simple wooden tool could actively assess a patient's health. This idea has led to... Read more


view channel
Image: The Atellica HEMA 570 and 580 hematology analyzers remove workflow barriers (Photo courtesy of Siemens)

Next-Gen Hematology Analyzers Eliminate Workflow Roadblocks and Achieve Fast Throughput

Hematology testing is a critical aspect of patient care, utilized to establish a patient's health baseline, track treatment progress, or guide timely modifications to care. However, increasing constraints... Read more


view channel
Image: Newly observed anti-FSP antibodies have also been found to predict immune-related adverse events (Photo courtesy of Calviri)

First Blood-Based Biomarkers Test to Predict Treatment Response in Cancer Patients

Every year worldwide, lung cancer afflicts over two million individuals and almost the same number of people succumb to the disease. This malignancy leads the charts in cancer-related mortalities, with... Read more


view channel
Image: The UNIQO 160 (CE-IVDR) advances diagnostic analysis for autoimmune diseases (Photo courtesy of EUROIMMUN)

Novel Automated IIFT System Enables Cutting-Edge Diagnostic Analysis

A newly-launched automated indirect immunofluorescence test (IIFT) system for autoimmune disease diagnostics offers an all-in-one solution to enhance the efficiency of the complete IIFT process, comprising... Read more


view channel
Electronic biosensor uses DNA aptamers for detecting biomarkers in whole blood samples (Photo courtesy of Freepik)

Electronic Biosensor Detects Biomarkers in Whole Blood Samples without Addition of Reagents

The absence of robust, reliable, and user-friendly bioanalytical tools for early and timely diagnosis of cardiovascular diseases, particularly sudden cardiac arrest, leads to preventable deaths and imposes... Read more


view channel
Image: The Coris acquisition provides Avacta with a broad, professional-use rapid test product portfolio (Photo courtesy of Coris Bioconcept)

Avacta Expands Diagnostics Portfolio with Acquisition of Rapid Test Maker Coris Bioconcept

Avacta Group plc (London, UK), a life sciences company developing oncology drugs and diagnostics, has acquired Coris Bioconcept SRL (Gembloux, Belgium) for an upfront cash consideration of GBP 7.... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.