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Image: The HaloPlex system enables fast, simple and efficient analysis of genomic regions of interest in a large number of samples (Photo courtesy of Agilent Technologies).

Mutations Identified As Cause for Rare Bone Marrow Disorder

Scientists have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder. The answer may allow some children to avoid the risk and expense of bone marrow transplantation, a common treatment for leukemia and bone marrow disorders. More...
09 Aug 2018
Image: The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies (Photo courtesy of PerkinElmer).

Homogeneous BTK Occupancy Assay Developed

Bruton’s tyrosine kinase (BTK), a member of the tyrosine kinase expressed in the hepatocellular carcinoma (TEC) family of cytoplasmic protein tyrosine kinases, was initially identified as the pathogenic protein in X-linked agammaglobulinemia, a human primary immune deficiency disease. More...
02 Aug 2018
Image: A blood smear from a patient with acute myeloid leukemia showing very large, immature myeloblasts with many nucleoli. A distinctive feature of these blasts is a linear red \"Auer rod\" composed of crystallized granules (Photo courtesy of University of Utah Medical School).

Acute Myeloid Leukemia Risk Predicted in Healthy Individuals

The incidence of acute myeloid leukemia (AML) increases with age and mortality exceeds 90% when diagnosed after age 65. Most cases arise without any detectable early symptoms and patients usually present with the acute complications of bone marrow failure. More...
25 Jul 2018
Image: A blood smear shows size heterogeneity of peripheral red blood cells, known as anisocytosis (Photo courtesy of Dr. Jay Park, MD).

Hematological Parameters Predict Severity of Acute Pancreatitis

Acute pancreatitis (AP) is an acute inflammation of the pancreatic parenchyma induced by activated pancreatic enzymes due to multiple causes. Current severity scores include multiple variables and some of them are only complete within 48 hours of admission. More...
23 Jul 2018
Image: A digitally colorized transmission electron microscopic (TEM) image of Zika virus, which is a member of the family, Flaviviridae. Virus particles, here colored blue, are 40nm in diameter, with an outer envelope, and an inner dense core (Photo courtesy of Cynthia Goldsmith).

FDA Recommends Pooled Blood Testing of Zika Screening

The US Food and Drug Administration said today that it has revised its recommendations for testing blood donations for the Zika virus. In a revised final guidance, the agency said that pooled testing of donations using a screening test that it has licensed is a sufficient method for complying with its testing regulations and effectively reducing the risk of Zika virus transmission. More...
17 Jul 2018
Image: The HumaStar 80 clinical chemistry analyzer (Photo courtesy of Human Diagnostics).

Biochemical Changes in Stored Donor Units Analyzed

Blood transfusion with allogeneic blood products is a common medical intervention to treat anemia or prepare patients for surgical procedures and generally, the blood units are secured and stored prior to expected transfusion. More...
12 Jul 2018
Image: The Procleix Panther system, a fully integrated and automated nucleic acid technology system for blood and plasma screening (Photo courtesy of Grifols Diagnostics).

Two Viral Blood Screening Assays Get FDA Clearance

A global producer of plasma-derived medicines and a developer of diagnostic solutions announced today that it has received approval from the U.S. Food & Drug Administration (FDA, Silver Springs, MD, USA; www.fda.gov) for two blood screening assays. More...
11 Jul 2018

The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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