We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
RANDOX LABORATORIES

Download Mobile App




Blood Test Identifies Prediabetics with Highest Risk of Developing Diabetes Before Symptoms Develop

By LabMedica International staff writers
Posted on 27 Feb 2023
Print article
Image: The GlycoMark test is a 10 minute, two-step enzymatic kinetic assay (Photo courtesy of Precision Diabetes)
Image: The GlycoMark test is a 10 minute, two-step enzymatic kinetic assay (Photo courtesy of Precision Diabetes)

Type 2 diabetes takes years to develop but is preventable if caught early. However, just 50% of people with prediabetes go on to develop full-blown diabetes over a period of 10 years. Unfortunately, current diabetes tests such as hemoglobin A1C and fasting glucose are incapable of accurately identifying prediabetic individuals who are at the highest risk of progression. Now, a blood test can identify high-risk, asymptomatic patients with prediabetes who cannot be detected by standard diabetes tests, hemoglobin A1C and glucose. The blood test meets a critical clinical need as it can be used by physicians to identify patients closest to developing type 2 diabetes and provide treatment to prevent the onset of the disease.

GlycoMark from Precision Diabetes, Inc. (Raleigh, NC, USA) is an FDA-cleared, non-fasting serum or plasma test for monitoring blood glucose variability in people with diabetes. The GlycoMark test provides quantitative measurement of 1,5-anhydroglucitol (1,5-AG) in serum or plasma. As the GlycoMark test reflects a progressive decline of functional beta-cell mass, it can identify prediabetic patients with the highest risk of developing diabetes before the first symptoms develop. Most high-risk patients can prevent the development of type 2 diabetes by making lifestyle changes such as eating a well-balanced diet, exercising and maintaining a healthy body weight.

In a new study, the GlycoMark blood test has shown that it can identify high-risk, asymptomatic patients with prediabetes, not detected by standard diabetes tests, hemoglobin A1C and glucose. The finding is extremely important as there is a significant clinical need for a sensitive and robust biomarker of functional beta-cell mass (beta cells are cells in the pancreas that produce insulin). A functional beta-cell mass biomarker is essential to identify which prediabetic individuals have the highest risk of progression to diabetes.

"This study not only has significant clinical implications as there has been a long search for an accurate biomarker of beta-cell function, but given the sheer numbers of people with prediabetes, it is important to target the highest-risk patients from a public health and economic standpoint," said Eric Button, CEO of Precision Diabetes, Inc. "GlycoMark will be an important tool in stratifying these patients for follow-up treatment."

Related Links:
Precision Diabetes, Inc. 

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Magnetic Bead Separation Modules
MAG and HEATMAG
Complement 3 (C3) Test
GPP-100 C3 Kit
New
Gold Member
TORCH Panel Rapid Test
Rapid TORCH Panel Test

Print article

Channels

Molecular Diagnostics

view channel
Image: Liquid biopsy could detect and monitor aggressive small cell lung cancer (Photo courtesy of Shutterstock)

Blood-Based Test Detects and Monitors Aggressive Small Cell Lung Cancer

Small cell lung cancer (SCLC) is a highly aggressive type of cancer known for its ability to metastasize. The behavior of tumors is largely governed by which genes are turned on, or transcribed, irrespective... Read more

Hematology

view channel
Image: The CAPILLARYS 3 DBS devices have received U.S. FDA 510(k) clearance (Photo courtesy of Sebia)

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Hemoglobinopathies, the most widespread inherited conditions globally, affect about 7% of the population as carriers, with 2.7% of newborns being born with these conditions. The spectrum of clinical manifestations... Read more

Immunology

view channel
Image: The groundbreaking treatment approach has shown promise in hard-to-treat cancers (Photo courtesy of 123RF)

Genetic Testing Combined With Personalized Drug Screening On Tumor Samples to Revolutionize Cancer Treatment

Cancer treatment typically adheres to a standard of care—established, statistically validated regimens that are effective for the majority of patients. However, the disease’s inherent variability means... Read more

Microbiology

view channel
Image: Microscope image showing human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color (Photo courtesy of Fred Hutch Cancer Center)

Mouth Bacteria Test Could Predict Colon Cancer Progression

Colon cancer, a relatively common but challenging disease to diagnose, requires confirmation through a colonoscopy or surgery. Recently, there has been a worrying increase in colon cancer rates among younger... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.