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Microbiology

Image: The BD FACSymphony A5 flow cytometer (Photo courtesy of BD Biosciences).

MAIT Cell Activation Dynamics Associated with COVID-19 Disease Severity

The balance between protective versus pathological immune responses in COVID-19 has been a concern since the onset of the pandemic. SARS-CoV-2 infection can lead to acute respiratory distress syndrome (ARDS), a condition characterized by aggressive inflammatory responses in the lower airways. More...
13 Oct 2020
Image: Yellow color shows thiamine degradation on an agar plate of cultured Paenibacillus thiaminolyticus (Photo courtesy of Catherine A. Richter, PhD).

Bacterium and Viral Coinfection Contributes to Postinfectious Hydrocephalus

Neonatal sepsis often precedes postinfectious hydrocephalus (PIH), although the manifestations of hydrocephalus typically emerge in the months after the neonatal period as sufficient cerebrospinal fluid (CSF) accumulates such that cranial expansion garners medical attention. More...
12 Oct 2020
Image: The ACL TOP 750 analyzer is for advanced automation and quality management in hemostasis testing (Photo courtesy of Instrumentation Laboratory).

Elevated Clotting Factor V Found with Severe COVID-19

Coagulopathy causes morbidity and mortality in patients with coronavirus disease 2019 (COVID‐19) due to severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection. Most doctors now know that COVID-19 can cause blood clots, potentially leading to paralysis, stroke, heart attack and death. More...
08 Oct 2020
Image: The Applied Biosystems ViiA 7 Real-Time PCR System combines all of the qPCR features in a single high performance instrument (Photo courtesy of Thermo Fisher Scientific).

Blood-Based Test Accurately Identifies Viral Infection Before Symptoms Develop

Acute viral infections are one of the most common reasons for visits to primary care physicians in high-income countries. The usefulness of traditional pathogen-focused diagnostic methods for viral infection (e.g., culture, serology, antigen detection, and PCR) is limited by the fact they can be slow, costly, and restricted in terms of breadth of pathogens detected. More...
07 Oct 2020
Image: Scanning electron microscope image shows SARS-CoV-2 (yellow) the virus that causes COVID-19, isolated from a patient in the USA, emerging from the surface of cells (pink) cultured in the laboratory (Photo courtesy of NIAID-RML).

RBC Distribution Width Associated with COVID-19 Mortality Risk

COVID-19 has a high rate of hospitalization, critical care requirement, and mortality. Identifying patients at highest risk for severe disease is important to facilitate early, aggressive intervention and to manage local hospital resources to mitigate the critical care crises that have impacted some hospital systems. More...
06 Oct 2020
Image: DPP Ebola Antigen System is a 15 minute rapid test for detection of Ebola Virus Specific Antigen (Photo courtesy of Chembio Diagnostic Systems).

Performance Compared for Three Ebola Rapid Diagnostic Tests

Ebola is a rare but deadly virus that causes fever, body aches, and diarrhea, and sometimes bleeding inside and outside the body. As the virus spreads through the body, it damages the immune system and organs. Ultimately, it causes levels of blood-clotting cells to drop. More...
01 Oct 2020
Image: A low level of potassium (K+), known as  hypokalemia, in the blood serum in COVID-19 patients is associated with disease severity and the need for invasive mechanical ventilation (Photo courtesy of Remedy Health Media).

Hypokalemia Is Associated With COVID-19 Severity

Early studies reported various electrolyte abnormalities at admission in patients who later presented the severe form of coronavirus disease 2019 (COVID-19). Electrolyte imbalance may not only affect patient care, but could provide insights into the COVID-19 pathophysiology. More...
01 Oct 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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