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BioResearch

Image: The bone marrow of mice with normal ether lipid production (top) contains more white blood cells than are found in the bone marrow of mice with ether lipid deficiency (bottom) (Photo courtesy of Washington University School of Medicine).

Inactivating Fatty Acid Synthase Reduces Inflammation by Interfering with Neutrophil Membrane Function

The enzyme fatty acid synthase was shown to regulate inflammation by sustaining neutrophil viability through modulation of membrane phospholipid composition.  More...
19 Jan 2015

Biotech Acquisition Designed to Accelerate the Development and Marketing of Immunosequencing Applications

Adaptive Biotechnologies, a developer of next-generation sequencing (NGS) to profile T-cell and B-cell receptors, has acquired of Sequenta, which is expected to expedite and expand the use of innovative immunosequencing technology for researchers and clinicians to diagnose, treat, and monitor patients with cancer, autoimmune disorders, and infectious diseases.  More...
19 Jan 2015
Image: Disc-shaped microparticles use monocytes to get to their destination (Photo courtesy of the University of California, Santa Barbara).

Novel Drug Delivery System Capitalizes on Monocytes' Ability to Penetrate Areas of Inflammation

A novel experimental drug delivery system is based on disc-shaped polymeric microparticles that are attached to monocytes, white blood cells that possess a unique ability to target and penetrate into sites of inflammation.  More...
18 Jan 2015

Strategic Alliance Will Promote Genetics Discovery Research

A major representative of the biotech industry will be collaborating with one of the United States' premiere research institutions in a 30 million USD strategic alliance to conduct genetics discovery research on the underlying causes of disease and to identify new treatment approaches.  More...
18 Jan 2015
Image: Mycobacterium tuberculosis (stained red) in sputum from a human patient (Photo courtesy of the CDC - US Centers for Disease Control and Prevention).

Combining Drugs Reduces Toxicity of Key Anti-Tuberculosis Therapy Option

Combining a potent drug used to treat multidrug-resistant tuberculosis with a calcium-channel blocker significantly reduces the required dosage of the anti-tuberculosis drug, which eliminates most of its toxic side effects.  More...
14 Jan 2015
Image: A new finding goes against dogma, showing for the first time that the building blocks of a protein, called amino acids, can be assembled by another protein, and without genetic instructions. The Rqc2 protein (yellow) binds tRNAs (dark blue, teal), which add amino acids (bright spot in middle) to a partially made protein (green). The complex binds the ribosome (white) (Photo courtesy of Janet Iwasa, PhD, University of Utah).

Challenging Classic Science Principles, New Research Finds New Role for Proteins

A new study revealed for the first time that the essential components of a protein, called amino acids, can be assembled without blueprints—DNA and an intermediate template called messenger RNA. Researchers have observed an instance in which another protein specifies which amino acids are added.   More...
14 Jan 2015
Image: Molecular structure of phosphatidylinositol (Photo courtesy of Wikimedia Commons).

Cancer Cells with p53 Mutations Have Phosphatidylinositol Signaling Molecules with Shortened Lipid Acyl Chains

A recent study showed that cancer cells with mutations in the p53 gene were distinguished by reduced-length fatty acid moieties in their cell membranes.  More...
13 Jan 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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