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BioResearch

Image: Eve, the robot scientist (Photo courtesy of the University of Manchester.

Robot Screening System Streamlines Discovery of New Drug Compounds

British drug developers have automated the drug discovery process by using a "robot scientist" to screen thousands of potential candidate compounds.  More...
23 Feb 2015
Image: The FLUOVIEW FVMPE-RS Gantry microscope (Photo courtesy of Olympus).

New Multiphoton Laser Scanning Microscope Configurations Expand Research Potential

Two new configurations of a state-of-the-art multiphoton laser scanning microscope extend the usefulness of the instrument for examining rapidly occurring biological events and for obtaining images from within cell cultures and tissues. More...
18 Feb 2015
Image: Programmable, self-assembled DNA nanoswitches serve both as templates for positioning molecules, and as sensitive, quantitative reporters of molecular association and dissociation. The figure depicts gel electrophoresis separation of linear and closed loop DNA strands (Photo courtesy of Harvard Medical School).

Low Cost Platform for Studying Molecular Interactions Based on DNA Gel Electrophoresis

A novel platform for studying molecular interactions is based on the separation of linear and circular forms of DNA by gel electrophoresis.  More...
18 Feb 2015
Image: Nanoparticles in low and high resolution micrographs (Photo courtesy of Green Laboratory, Johns Hopkins University).

Nanoparticles Deliver Viral Gene That Activates Toxic Drug Inside Brain Cancer Cells

Cancer researchers have described a nanoparticle-based gene therapy system that inserted the gene for the enzyme herpes simplex virus type I thymidine kinase into brain tumor cells and rendered them highly sensitive to the chemotherapeutic agent ganciclovir.  More...
17 Feb 2015

Protein Interactions Help Prevent Arterial Blockage

The protein alpha-1-microglobulin helps to prevent development of arteriosclerosis by inhibiting the oxidation of LDL that is induced by the combination of myeloperoxidase and hydrogen peroxide.  More...
17 Feb 2015
Image: Using the compact multi-organ chip (comparable in size to a one-euro piece), and those of three separate microcircuits, researchers can study the regeneration of certain kidney cells (Photo courtesy of Fraunhofer Institute for Material and Beam Technology IWS).

Mini-Organism-on-a-Chip May Replace Test Animals in Drug Studies

A team of German biomedical researchers has developed a highly miniaturized micro-circulatory system for testing the response of various body organs to drugs or other chemicals.  More...
16 Feb 2015
Image: PKC-zeta intestinal cancer stem cell regulation (Photo courtesy of Sanford-Burnham Medical Research Institute).

Lack of Stem Cell Regulator Leads to Intestinal Cancer in Mouse Model

The interaction of the enzyme protein kinase C-zeta with the enzymes Yap and beta-catenin was found to be a key regulator of intestinal stem cell function and the point where normal cell replacement could give rise to cancerous growth.  More...
15 Feb 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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