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BioResearch

Image: The three types of heart cells—cardiomyocytes, endothelial cells, and smooth muscle cells—created from ieCPCs (Photo courtesy of Dr. Yu Zhang, Gladstone Institutes).

Stem Cell Therapy Repairs Damaged Heart Muscle in Mouse Myocardial Infarction Model

Advanced stem cell techniques were used to generate expandable cardiovascular progenitor cells from skin fibroblasts, which could repair damage to the heart muscle caused by myocardial infarction.  More...
13 Mar 2016
Image: Loss of the DJ-1 gene in nerve cells (green) impairs the transport of mitochondria (red) and important metabolic pathways of the cellular respiration (Photo courtesy of the University of Luxembourg).

Reduced Antioxidant Protection Leads to Neuron Loss in Parkinson's Disease

Lack of antioxidant protection in brain cells due to mutations that prevent the expression of the protein encoded by the oncogene DJ-1 has been linked to premature aging of neurons in Parkinson's disease patients.  More...
13 Mar 2016
Image: Scanning electron micrograph of Leptospira sp. Bacteria (Photo courtesy of the CDC - US Centers for Disease Control and Prevention).

Asymptomatic Individuals May Shed Infective Leptospira Bacteria in Their Urine

An international team of molecular microbiologists has assembled a comprehensive, cross-species genomic comparison of all 20 known species of Leptospira and determined that a pool of asymptomatic individuals was shedding the bacteria in their urine.   More...
09 Mar 2016
Image: Reprogrammed stem cells (green) chase down and kill glioblastoma cells (pink), potentially offering a new and more effective treatment option for a disease that has not had any in more than 30 years (Photo courtesy of the University of North Carolina).

Stem Cell Therapies Improve Survival of Mouse Brain Cancer Model

Two papers have described the use of fibrin-embedded, biologically engineered induced neural and mesenchymal stem cells in tumor-homing cytotoxic stem cell therapy that shows promise as a new approach for treating the incurable brain cancer glioblastoma multiforme.  More...
09 Mar 2016
Image: Intermediate-magnification micrograph of an osteosarcoma (center and right of image) adjacent to nonmalignant bone (left-bottom of image) (Photo courtesy of Wikimedia Commons).

MicroRNA-Nanoparticle Complexes Prevent Growth of Osteosarcoma Cells

Cancer researchers developed a nanoparticle delivery system to transport dormancy-inducing microRNAs into osteosarcoma cells.  More...
08 Mar 2016
Image: Structure of the beta-secretase-inhibitor complex (Photo courtesy of Wikimedia Commons).

Potential Alzheimer's Disease Drug Selectively Blocks Endosomal Beta-Secretase Activity

Alzheimer's disease researchers have developed a drug that blocks the disease-related activity of the enzyme beta-secretase without affecting other interactions that are not related to AD.  More...
08 Mar 2016
Image: Progressively spaced micropillars highlight the new magnetic ratcheting cell sorting system (Photo courtesy of University of California, Los Angeles).

Researchers Reveal a Microchip Magnetic Cell Sorting Device

A novel magnetic cell sorting system may potentially be reduced in size for development into a "lab-on-a-chip" device.  More...
07 Mar 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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