We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
LGC Clinical Diagnostics

Download Mobile App




Protein Patterns in Blood Can Predict IBD As Early As 16 Years Before Diagnosis

By LabMedica International staff writers
Posted on 27 Nov 2024
Print article
Image: Specific protein patterns in the blood can predict IBD up to 16 years before onset (Photo courtesy of 123RF)
Image: Specific protein patterns in the blood can predict IBD up to 16 years before onset (Photo courtesy of 123RF)

Inflammatory bowel disease (IBD) is particularly challenging because it can progress for years without showing symptoms, leading to damage in the gastrointestinal tract before treatment begins. Now, scientists have discovered specific protein patterns in blood that can predict IBD up to 16 years before it is diagnosed. This is especially true for Crohn’s disease, which can be detected with remarkable accuracy.

Researchers at Örebro University (Örebro, Sweden) analyzed nearly 800 blood samples and identified distinct protein patterns that differentiate healthy individuals from those who later develop Crohn’s disease or ulcerative colitis. Their findings revealed that a particular combination of 29 proteins could predict Crohn’s disease with high accuracy. In contrast, predicting ulcerative colitis proved to be more difficult. The study showed that changes in protein patterns could be detected in individuals with Crohn’s disease as early as 16 years before diagnosis. According to the research published in Gastroenterology, the results emphasize that proteins related to intestinal barrier function and the immune system play a critical role in understanding the development of Crohn’s disease.

“We’ve taken an important step towards us being able to predict and prevent these diseases at a very early stage in the future,” said Jonas Halfvarson, professor of gastroenterology at Örebro University, and lead researcher of the study. “By discovering these markers long before symptoms make themselves known, we can potentially intervene earlier and hopefully improve quality of life for those individuals that risk developing IBD.”

Gold Member
Blood Gas Analyzer
GEM Premier 7000 with iQM3
Antipsychotic TDM AssaysSaladax Antipsychotic Assays
New
Silver Member
Oncology Molecular Diagnostic Test
BCR-ABL Dx ELITe MGB Kit
New
Liquid Based Cytology Production Machine
LBP-4032

Print article

Channels

Clinical Chemistry

view channel
Image: The new saliva-based test for heart failure measures two biomarkers in about 15 minutes (Photo courtesy of Trey Pittman)

POC Saliva Testing Device Predicts Heart Failure in 15 Minutes

Heart failure is a serious condition where the heart muscle is unable to pump sufficient oxygen-rich blood throughout the body. It ranks as a major cause of death globally and is particularly fatal for... Read more

Hematology

view channel
Image: The smartphone technology measures blood hemoglobin levels from a digital photo of the inner eyelid (Photo courtesy of Purdue University)

First-Of-Its-Kind Smartphone Technology Noninvasively Measures Blood Hemoglobin Levels at POC

Blood hemoglobin tests are among the most frequently conducted blood tests, as hemoglobin levels can provide vital insights into various health conditions. However, traditional tests are often underutilized... Read more

Immunology

view channel
Image: Concept for the device. Memory B cells able to bind influenza virus remain stuck to channels despite shear forces (Photo courtesy of Steven George/UC Davis)

Microfluidic Chip-Based Device to Measure Viral Immunity

Each winter, a new variant of influenza emerges, posing a challenge for immunity. People who have previously been infected or vaccinated against the flu may have some level of protection, but how well... Read more

Microbiology

view channel
Image: A new test finds bacteria in liquids and indicate their presence by changing color (Photo courtesy of Georgia Kirkos/McMaster University)

New Hands-Free Rapid Test Detects Bacteria in Fluids

Bacteriophages, the most abundant form of life on Earth, are specialized to target and destroy specific types of bacteria. Their natural ability to fight bacteria has long been harnessed to treat infections.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.