We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




Newly Identified Genes May Help to Screen and Treat Individuals with Hearing Loss

By LabMedica International staff writers
Posted on 17 May 2022

A massive genome-wide association study (GWAS) identified 10 novel gene loci associated with hearing loss, which may aid in screening and treating the disorder. More...

Hearing loss is one of the top contributors to years lived with disability and is a risk factor for developing dementia. Hearing loss is a major medical problem worldwide with an estimated 2.4 billion individuals expected to have some form of hearing loss by the year 2050.

Molecular evidence on the cellular origins of hearing loss in humans is growing. In this regard, investigators at King's College London (United Kingdom) and colleagues at Karolinska Institute (Stockholm, Sweden) and Erasmus University (Rotterdam, Netherlands) performed a genome-wide association meta-analysis of clinically diagnosed and self-reported hearing impairment on 723,266 individuals. The study comprised 147,997 affected individuals and 575,269 control subjects including 60,941 affected individuals that were not included in a previously published GWAS meta-analysis.

Results of the meta-analysis revealed 48 genes linked to hearing loss, including 10 novel variants newly linked to hearing.

Contributing author Dr. Frances Williams, professor of genomic epidemiology at King's College London, said, "Our findings identify 10 genes newly linked with hearing loss. This study points to genes we could target for screening purposes, drug development. and even gene therapy in the future. This study provides a solid foundation for ultimately improving therapies against hearing loss."

The study was published in the May 16, 2022, online edition of the American Journal of Human Genetics.

Related Links:
King's College London 
Karolinska Institute 
Erasmus University 

 


Gold Member
Hematology Analyzer
Medonic M32B
Portable Electronic Pipette
Mini 96
6 Part Hematology Analyzer with RET + IPF
Mispa HX 88
Gram-Negative Blood Culture Assay
LIAISON PLEX Gram-Negative Blood Culture Assay
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Hematology

view channel
Image: New evidence shows viscoelastic testing can improve assessment of blood clotting during postpartum hemorrhage (Photo courtesy of 123RF)

Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage

Postpartum hemorrhage, severe bleeding after childbirth, remains one of the leading causes of maternal mortality worldwide, yet many of these deaths are preventable. Standard care can be hindered by delays... Read more

Immunology

view channel
Image: When assessing the same lung biopsy sample, research shows that only 18% of pathologists will agree on a TCMR diagnosis (Photo courtesy of Thermo Fisher)

Molecular Microscope Diagnostic System Assesses Lung Transplant Rejection

Lung transplant recipients face a significant risk of rejection and often require routine biopsies to monitor graft health, yet assessing the same biopsy sample can be highly inconsistent among pathologists.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.