Hidden Vitamin in Beer May Prevent Obesity

The researchers succeeded in showing that NR was capable of all of these functions, culminating in enhanced oxidative metabolism and protection against high-fat diet-induced metabolic abnormalities.

Mice on a high-fat diet fed NR over a ten-week period gained significantly less weight (60%) than mice eating the same diet, but without NR supplementation. In addition, none of the NR-treated mice had indications that they were developing diabetes, unlike the untreated mice. The mice fed NR supplements also had better endurance performance and improved energy expenditure compared to those who had not received the vitamins; and no side effects were evident in mice given the NR supplement. The study was published on June 6, 2012, in Cell Metabolism.

“The results indicate that the natural vitamin NR could be used as a nutritional supplement to ameliorate metabolic and age-related disorders characterized by defective mitochondrial function,” concluded lead author Carles Canto, PHD, of the EPFL. “Cells use what they need when they need it, and the rest is set aside without being transformed into any kind of deleterious form.”

The researchers believe that the increase in the NR molecule leads to an improvement in mitochondrial function, which is also believed to play a role in the aging process, and hypothesize that by stimulating mitochondrial with the NR molecule, longevity, as well as other health aspects, will also be improved.

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Federal Polytechnic School of Lausanne