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Technology

Image: The Holomics Reader HRDR-300 mobile device was used to measure fluorescent intensity of the quantum dots complex after lateral migration of patient serum (Photo courtesy of Medical College of Georgia).

POC Test Based on Quantum Dots Detects Antibody Responses

Point-of-care (POC) assays, which can be performed at or near the site of care with a rapid turnaround time, are pivotal to transforming global disease control efforts, particularly in resource-constrained settings where access to laboratory facilities is limited. More...
31 Oct 2019
Image: The Aurora advanced flow cytometry system is now available with five lasers to enable seeing more than 30 colors from a single sample (Photo courtesy of Cytek Biosciences).

Flow Cytometry Improved Updated Spectral Analyzer

Flow cytometry aims to count the number, size, granularity, and other properties of cells in a heterogeneous population. Standard flow cytometry lasers excite certain fluorescent markers (fluorochromes, antibodies, or stains) on a cell as it passes through the beam. More...
31 Oct 2019
Image: Representative negative-stained transmission electron microscopy images of 4R RT-QuIC products seeded with brain homogenates from individuals with the designated diseases – frontotemporal dementia and Parkinsonism linked to chromosome 17; corticobasal degeneration; and progressive supranuclear palsy (Photo courtesy of National Institute of Allergy and Infectious Diseases).

CSF Test Developed for Uncommon Brain Diseases

Scientific studies have linked the abnormal deposition of tau in the brain to at least 25 different neurodegenerative diseases. However, to accurately diagnose these diseases, brain tissue often must be analyzed after the patient has died. More...
30 Oct 2019
Image: Diagram workflow for co-amplification at lower denaturation temperature PCR (COLD-PCR)/fluorescence melting curve analysis (FMCA) (Photo courtesy of The First Affiliated Hospital of Fujian Medical University).

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. More...
23 Oct 2019
Image: An example of an FTIR spectrometer with an attenuated total reflectance (ATR) attachment (Photo courtesy of Wikimedia Commons).

Infrared Spectrometry Method Used for Triage of Brain Cancer Patients

A team of British researchers has adapted an advanced spectrophotometric method for use in brain cancer testing as a triage tool to speed up the diagnostic process. More...
23 Oct 2019
Image: The BioPhotometer 6131 spectrophotometer/fluorometer (Photo courtesy of Eppendorf).

PCR Kit Developed for Detection of Q-fever Pathogen

Coxiella burnetii is an obligate intracellular bacterium that causes Q fever in animals and humans. The infection results from inhalation of a spore-like small-cell variant, and from contact with the milk, urine, feces, vaginal mucus or semen of infected animals. More...
17 Oct 2019
Image: A test to detect opioid drugs in exhaled breath was developed. In this photograph, a volunteer breathes normally into the human breath sampler. Samples are frozen before being taken to the laboratory for analysis (Photo courtesy of Dr. Cristina Davis, University of California, Davis).

Breath Analysis May Replace Blood Sampling to Monitor Drug Usage

A simple and non-invasive technique to collect exhaled breath condensate (EBC) from chronic pain patients was developed, and its usefulness was confirmed by comparing metabolites in breath and blood samples following use of different analgesic opioid drugs. More...
14 Oct 2019
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