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Image: Equipment required for the smaRT-LAMP testing technology would cost less than USD100 (Photo courtesy of Michael Mahan, PhD)

Rapid COVID Test Developed Solves Problems With LAMP Sensitivity

Researchers from the University of California, Santa Barbara have developed an isothermal amplification-based SARS-CoV-2 and influenza test that could retail for as little as $2 while addressing a key problem with loop-mediated isothermal amplification tests — false positive results. More...
14 Feb 2022
Image: Gene fusions play a key role in the formation and spread of nearly 20% of all human cancers. This schematic shows the ways a fusion gene can occur at a chromosomal level (Photo courtesy of Wikimedia Commons)

RNA Sequencing Improves Gene Fusion Detection for Childhood Cancer Diagnostics

Analysis of whole tumor RNA in children with cancer significantly increases the detection of gene fusions, which can provide information concerning the exact cancer type, the aggressiveness of the tumor, and the possible benefit of targeted drugs. More...
07 Feb 2022
Image: (a) 3D-rendered exploded view of autohaem smear showing the non-3D printed parts. (b) Photo of an autohaem smear showing the assembled device with the two microscope slides in their positions (Photo courtesy of Cambridge University)

Automating Blood Smears Developed for Easier Malaria Diagnosis

Blood smears are used in diagnosis for a variety of hematological disorders, such as anemia and leukemia. They are also the preferred method of diagnosis of parasitic infections, such as malaria and filariasis in developing world laboratories. More...
03 Feb 2022
Image: Schematic diagram of image-enabled cell sorting, developed at BD Biosciences and  tested by European Molecular Biology Laboratory (Photo courtesy of BD Bioscience)

High-Speed Fluorescence Image-Enabled Cell Sorting Tested

Cell sorting through flow cytometry is a technique that enables scientists to identify and sort individual cells based on specific characteristics of each cell in order to study them in more detail, evaluate how each cell may react to a new drug or perform other single cell studies. More...
03 Feb 2022
Image: Highly Sensitive Immuno-CRISPR Assay Developed for CXCL9 Detection Helps Diagnose Early Kidney Transplant Rejection (Photo courtesy of Rensselaer Polytechnic Institute)

Immuno-CRISPR Assay Helps Diagnose Early Kidney Transplant Rejection

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage. More...
20 Jan 2022
Image: Optimized reaction time for Multiple Cross Displacement Amplification (MCDA-LFB) assay to detect Legionella pneumophila. The best sensitivity was seen when the amplification lasted for 35 minutes (Photo courtesy of Zhejiang Provincial People’s Hospital)

MCDA-LFB Assay Developed for Rapid Detection of Legionnaires’ Disease

Legionella pneumophila is an opportunistic waterborne pathogen of significant public health problems, which can cause serious human respiratory diseases (Legionnaires’ disease). Legionnaires’ disease is characterized by severe lung infection symptoms, including severe pneumonia with a high fatality rate. More...
18 Jan 2022
Image: The UBC Rapid is a qualitative test to detect cytokeratin fragments 8 and 18 in urine for bladder cancer detection (Photo courtesy of IDL Biotech)

Nomograms Including Rapid Antigen Test Detects Primary Bladder Cancer

Urinary bladder cancer (BC) is the tenth most prevalent cancer affecting mainly the elderly and men. The suspicion of BC often arises after the detection of microscopic or macroscopic (gross) hematuria during a patient’s examination. More...
04 Jan 2022
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