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Immunology

Image: PLATEILA DENGUE NS1 AG: Qualitative or semi-quantitative detection of dengue virus NS1 antigen in human serum or plasma by enzyme immunoassay (Photo courtesy of Bio-Rad).

Dengue Virus IgM Serotyped by ELISA

Dengue virus (DENV) is an arthropod-borne flavivirus that is endemic in tropical and subtropical regions, causing hundreds of millions of infections annually. It is subdivided into four serotypes, DENV-1–4. After infection, patients have lifelong immunity against the homologous serotype but remain susceptible to infections with the others. More...
03 Jan 2019
Image: SureSelect Target Enrichment Systems (Photo courtesy of Agilent Technologies).

Genetic and Epigenetic Features Found in Glioma Tumors

Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder that is characterized by cutaneous findings, most notably café-au-lait spots and axillary freckling, by skeletal dysplasias, and by the growth of both benign and malignant nervous system tumors, most notably benign neurofibromas. More...
27 Dec 2018
Image: The Simoa HD-1 Analyzer is a fully automated instrument for running immunoassays (Photo courtesy of Quanterix).

Urinary Biomarkers for Tuberculosis Explored

The gold standard for tuberculosis (TB) diagnosis is the isolation in culture of Mycobacterium tuberculosis in biological samples. However, culture is time consuming and does not accomplish the need of quickly and properly starting treatment, it is not always feasible in extra-pulmonary TB and it is difficult to carry out in resource-limited settings. More...
25 Dec 2018
Image: The Lumipulse G 25-OH Vitamin D is an immunoreaction cartridge for in vitro diagnostic for the quantitative determination of 25-hydroxyvitamin D (25(OH)D) in human serum or plasma to be used in the assessment of Vitamin D sufficiency (Photo courtesy of Fujirebio).

Vitamin D Measured in Patients with Diabetic Foot

Peripheral artery disease (PAD) is the underlying predisposing factor in the etiology of the majority of diabetic feet. Vitamin D plays a role in calcium and bone metabolism and it is known to be an important immune modulator agent. More...
19 Dec 2018
Image: Patients with inflammatory bowel disease who have an elevated PSA, may be at risk for prostate cancer (Photo courtesy of Harvard University).

Inflammatory Bowel Disease Linked to Prostate Cancer

About one million men have inflammatory bowel disease in the USA, a common chronic condition that includes Crohn's disease and ulcerative colitis. Epidemiologic studies have noted an association between chronic inflammation and prostate cancer. More...
18 Dec 2018
Image: A section from the hippocampus of an Alzheimer’s disease patient stained with a tau antibody (TNT1). Note the classical triad of tau pathologies in AD, 1) neurofibrillary tangles (arrowheads), 2) neuropil threads (arrows), and 3) a neuritic plaque (asterisk) (Photo courtesy of Michigan State University).

Tau Blood Test Developed for Alzheimer's Disease

Presently, the only way to definitively diagnose Alzheimer's disease in life is through brain scans and tests of cerebrospinal fluid that must be collected via lumbar puncture. Though cumbersome and expensive, such tests provide the most accurate diagnoses for patients. More...
17 Dec 2018
Image: A histopathology of Strongyloides stercoralis in the duodenum (Photo courtesy of Dr. Raul S. Gonzalez, MD).

Strongyloidiasis Antibodies Found in Transplant Donors

Strongyloidiasis is a neglected tropical disease caused by a parasite, which is endemic in most parts of the world. It can cause a life-threatening disease among immunosuppressed individuals and can be transmitted from solid organ transplant (SOT) donors to recipients. More...
10 Dec 2018
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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