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Immunology

Image: Defective Selection of Autoreactive B Cells seen in Systemic Lupus Erythematosus (Photo courtesy of Sebastian Kaulitzki).

Early B Cell Differentiation Activation Seen in Lupus

In people with systemic lupus erythematosus, their B cells, part of the immune system, are abnormally activated. They produce antibodies that react against their own tissues, causing a variety of symptoms, such as fatigue, joint pain, skin rashes and kidney problems. More...
17 Jul 2019
Image: QuantiFERON-TB Gold (QFT) is an innovative blood test that measures the cell-mediated immune response of Mycobacterium tuberculosis infected individuals (Photo courtesy of Qiagen).

TB Tests May Not Detect Infection in Exposed Individual

Mycobacterium tuberculosis is the leading infectious cause of death worldwide Exposure to M. tuberculosis results in heterogeneous clinical outcomes including primary progressive tuberculosis (TB) and latent tuberculosis infection (LTBI). More...
17 Jul 2019
Image: An example of an ELISA test kit designed for quantitative determination of the concentration of human interleukin 6 (IL-6) in serum and plasma (Photo courtesy of Thermo Fisher Scientific).

Blood Biomarkers Help Predict Recovery Time after Concussion

A study of high school and college football players suggests that biomarkers in the blood may have potential use in identifying which players are more likely to need a longer recovery time after concussion. More...
17 Jul 2019
Image: A 3D-reconstructed image of a doublet of a T cell (CD3, green) and a monocyte (CD14) (Photo courtesy of La Jolla Institute for Immunology).

Circulating T Cell-Monocyte Complexes Indicate Immune Perturbations

Communication between immune cells is a major component of immune responses, either directly through cell-cell contacts or indirectly through the secretion of messenger molecules such as cytokines. More...
10 Jul 2019
Image: The RealStar Zika Virus reverse transcription polymerase chain reaction (RT-PCR) (Photo courtesy of Altona Diagnostics).

Whole-Blood Testing Diagnoses Acute Zika Virus Infections

Zika virus infections are linked to congenital malformations in neonates from mothers infected during pregnancy and to neurologic disorders in adults. Reverse transcription polymerase chain reaction (RT-PCR) is the most reliable method for confirming Zika virus infections. More...
04 Jul 2019
Image: A scanning electron photomicrograph of Candida albicans yeast cells (Photo courtesy of Science Photo Library).

Immune-Related Gene Implicated in Chronic Candida Infection Risk

Candida vaginitis is a frequent clinical diagnosis with up to 8% of women experiencing recurrent vulvovaginal candidiasis (RVVC) globally. RVVC is characterized by at least three episodes per year. More...
26 Jun 2019
Image: Lupus Erythematosus (LE) Cells are neutrophils that have engulfed lymphocyte nuclei coated with and denatured by antibody to nucleoprotein (Photo courtesy of Dr. Moustafa Abdou).

Cardiovascular Risk Biomarkers Found for JSLE Patients

Systemic lupus erythematosus is an autoimmune disease typically affecting women between the ages of 15 and 50, and symptoms flare up unpredictably. Approximately 20% of cases begin during childhood and in these patients the disease is suggested to be more severe. More...
25 Jun 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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