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Immunology

Image: A diagram of urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment (Photo courtesy of University College London).

Urine Biopsies Help Monitor Bladder Cancer Treatment

Despite the advances in cancer immunotherapy, only a fraction of patients with bladder cancer exhibit responses to checkpoint blockade, highlighting a need to better understand drug resistance and identify rational immunotherapy combinations. More...
10 Oct 2018
Image: CT45, a biomarker marker found in some ovarian cancer cells, is associated with extended disease-free survival for women with advanced ovarian cancer (Photo courtesy of University of Chicago Medical Center).

Ovarian Cancer Biomarker Predicts Therapy Response

Despite months of aggressive treatment involving surgery and chemotherapy, about 85% of women with high-grade widespread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but never to a cure. About 15% of patients, however, do not have a recurrence and most of those women remain disease free for years. More...
01 Oct 2018
DIASOURCE (A Biovendor Company)
Image: An ELISA Kit for Kidney Injury Molecule 1 (Kim1) (Photo courtesy of Enzo Life Sciences).

Blood Test May Help Detect Kidney Cancer Earlier

Renal cell carcinoma (RCC) has the potential for cure with surgery when diagnosed at an early stage. Kidney injury molecule-1 (KIM-1) has been shown to be elevated in the plasma of RCC patients. More...
26 Sep 2018
Image: The Immage 800 immunochemistry system (Photo courtesy of Beckman Coulter).

Biomarkers Correlated with Idiopathic Inflammatory Myopathy

Patients with idiopathic inflammatory myositis (IIM) typically present with muscle weakness, myalgia and in case of dermatomyositis (DM) also skin involvement. Arthralgia is often present, but the articular manifestations are usually mild and non-destructive. More...
25 Sep 2018
Image: High magnification micrograph of senile cardiac amyloidosis from an autopsy specimen (Photo courtesy of Nephron).

Novel Biomarkers Predict CV Events in Type 2 Diabetes

Cardiovascular disease generally refers to conditions that involve narrowed or blocked blood vessels that can lead to a heart attack, chest pain (angina) or stroke. Cardiovascular disease (CVD) risk prediction represents an increasing clinical challenge in the treatment of diabetes. More...
20 Sep 2018
Image: Immunostaining of Helicobacter pylori infection in the small intestine. The small spiral-curved shaped bacterium can be seen clearly using a ×100 oil objective under the microscope (Photo courtesy of BioCare Medical).

Tumor Markers Associated with H. Pylori Infection

Helicobacter pylori infection is a major cause of several cancers such as gastric, pancreatic and lung. The relationship between H. pylori and tumor markers continues to remain unclear. As one of the leading causes of morbidity and mortality globally, cancer represents a major detrimental public health problem worldwide. More...
19 Sep 2018
Image: The Vitros 5600 integrated system for blood analysis (Photo courtesy of Ortho Clinical Diagnostics).

High Levels of Aldosterone Increase Risk of Diabetes

Increased levels of aldosterone, the main mineralocorticoid hormone, is already associated with hypertension, can play a significant role in the development of diabetes, particularly among certain racial groups. More...
19 Sep 2018
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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