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BioResearch

Image: Structure of the ferritin complex. The toxic anticancer drug daunorubicin was sequestered at the core of the molecule, protected by the protein coat (Photo courtesy of Wikimedia Commons).

Apoferritin-Based Nanocapsules Used to Transport Toxic Anticancer Drug

A toxic anticancer therapeutic agent was encapsulated in capsules derived from apoferritin, which sequestered the drug until its selective delivery to cancer cells.  More...
08 Nov 2015
Image: Comparison of a knockout obese mouse (left) and a normal laboratory mouse (right). Lipid metabolism in mice was shown to be regulated by a group of microRNAs (Photo courtesy of Wikimedia Commons).

MicroRNAs Shown to Control Lipid and Cholesterol Metabolism in Mouse Models

A group of microRNAs was identified as modulators of lipid and cholesterol metabolism in two mouse models and may serve as targets for drugs designed to protect against cardiovascular diseases.  More...
08 Nov 2015

European Biopharmaceutical Companies to Collaborate on Cancer Drug Development

Two European-based biopharmaceutical companies have agreed to collaborate on the development of new anticancer therapeutic agents.  More...
08 Nov 2015
Image: In these mouse embryo cells, XistAR RNA strands show up in red, and the Xist RNA whose production they trigger show up in green (Photo courtesy of University of Michigan).

Antisense RNA Found That Controls the X Chromosome Inactivation Regulator

Genomics researchers have learned how one of a female's two X chromosomes is rendered inactive, which prevents development of most diseases linked to X chromosome genetic defects.  More...
04 Nov 2015
Image: Photomicrograph of a kidney organoid (one millimeter diameter) grown from a patient\'s stem cells (Photo courtesy of Brigham and Women\'s Hospital).

3D Organoid Cultures to Serve as Model System for Kidney Disease Research

By combining an advanced genome editing technique with stem cell technology cell biologists have succeeded in establishing the growth in culture of functional three-dimensional kidney-like organoids and spheroids.  More...
04 Nov 2015
Image: Atopic dermatitis of the inside crease of the elbow (Photo courtesy of Wikimedia Commons).

Additional Genetic Loci Linked to Development of Atopic Dermatitis

A large genomic study linked added 10 genetic loci to the 21 already known that indicate risk of developing the chronic skin disease atopic dermatitis.  More...
03 Nov 2015
Image: Researchers have developed a technique that detects a pair of markers for glioblastoma, a type of brain cancer. Left: Cancerous cells are marked with green (blue shows cell nucleus but does not indicate cancer). Right: When only epidermal growth factor receptor is detected in the same sample, the cancer signal is much less obvious (Photo courtesy of Weibo Cai laboratory, University of Wisconsin).

Bispecific Antibody Boosts Sensitivity of Brain Cancer PET Scans

A bispecific antibody was developed that is taken up by glioblastoma cells in a manner that increases the specificity and intensity of signals detected by PET scanning.  More...
03 Nov 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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