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BioResearch

Image: A four milliliter sample of hyperlipidemic blood with lipids separated into the top fraction (Photo courtesy of Wikimedia Commons).

Blocking Phosphatidylcholine Synthesis Lowers Levels of Circulating Lipids in Mouse Hyperlipidemia Model

Cardiovascular disease researchers seeking new ways to treat hyperlipidemia found that inhibition of the gene encoding a protein required for biosynthesis of phosphatidylcholine, a major cell membrane component, in a mouse model resulted in decreased levels of lipids in circulation.   More...
21 Sep 2015
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Novel Spin Column-Based Kits for Standardized Extraction of Exosome RNA

A novel spin column-based method has been developed that provides a faster, more reliable means for the isolation of RNA from exosomes for research, delivering high-quality results with less labor-intensive sample preparation.  More...
21 Sep 2015
Image: Without angiogenesis a tumor cannot grow beyond a limited size (Photo courtesy of Wikimedia Commons).

Blocking the MicroRNA That Controls Angiogenesis Slows Breast Tumor Growth in a Diabetic Mouse Model

A team of molecular biologists demonstrated that it was possible to inhibit growth of breast tumors in a diabetic mouse model by injecting the animals with an antagonist of the microRNA that controls the process of angiogenesis.  More...
20 Sep 2015
Image: A small liquid plug in the bronchus was manipulated by air ventilation to deliver a drug into the most distant alveoli (Photo courtesy of Dr. Jinho Kim, Columbia University).

Mathematical Models Guide Microliter Doses of Drugs to Specific Pathological Sites in the Lungs

A recent paper described a novel technique for precise delivery of microliter quantities of drugs directly to selected pathological areas in the lungs.  More...
16 Sep 2015
Image: The \"Japonica Array\" contains 659,253 SNPs, including tag SNPs for imputation, SNPs of Y chromosome and mitochondria, and SNPs related to previously reported genome-wide association studies and pharmacogenomics (Photo courtesy of Tohoku Medical Megabank Organization).

Custom-Designed SNP Array Facilitates Japanese Genomic Studies

Japanese genomic researchers have created a single nucleotide polymorphism array optimized for studies on the Japanese population.  More...
16 Sep 2015
Image: During the process of cell division, the mitochondria are damaged (yellow indicator) making the cells particularly dependent on glucose as a source of energy. Genetic material is shown in blue and mitochondria in red (Photo courtesy of the Spanish National Cancer Research Center).

Blocking Glycolysis Helps Antimitotic Chemotherapeutic Drugs to Work Better

Blocking the attempts of tumor cells to establish glycolysis as their primary means of generating energy was found to significantly augment the chemotherapeutic benefits of drugs that prevent the cells from dividing.  More...
15 Sep 2015
Image: The Brazilian social wasp Polybia paulista is the source of the Polybia-MP1 anticancer peptide (Photo courtesy of Dr. Mario Palma, Sao Paulo State University).

Toxic Peptide from Wasp Venom Targets Cancer Cell Membrane Phospholipids

A toxic peptide component of the venom produced by a South American wasp effectively destroys some types of cancer cells through interactions with groups of phospholipids that are distributed abnormally on their cell membranes.  More...
15 Sep 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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