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BioResearch

Image: Phase and T immunofluorescence images of mesoendoderm patterns in different drug test groups on day 3. The morphology of the mesoendoderm pattern was significantly disrupted under teratogen (Thalidomide, RA, D-penicillamine, or VPA) treatment in a dose-dependent manner; whereas under non-teratogen (Penicillin G) treatment, the structure of the mesoendoderm pattern remained unchanged. Scale bar = 200 μm (Photo courtesy of Xing J et al. 2015 and Institute of Bioengineering and Nanotechnology, Singapore).

Embryonic Development “In a Dish” – Recreating Two Key Processes

In a biotechnological advancement involving human pluripotent stem cells and geometric restriction, researchers have for the first time developed animal-free platforms to help screen for and study drugs that cause birth defects.  More...
21 Oct 2015
Image: A new technique enabled growth of aged brain cells from patients’ skin cells. The micrograph shows induced neurons that were directly converted from skin fibroblasts obtained from elderly human donors (Photo courtesy of the Salk Institute for Biological Studies).

Directly Differentiated Neurons Maintain Precursor Cells' Genetic Aging Pattern

Advanced stem cell techniques allow direct inducement of neurons that maintain the genetic pattern of aging that was present in the precursor skin fibroblasts and which may be used to model age-related neurological diseases.  More...
21 Oct 2015

New Platform Detects MicroRNA Directly in Serum and Plasma

Biotech and other life science researchers will benefit from the introduction of a novel microRNA detection platform.  More...
20 Oct 2015
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Enhanced Cuvette-Free UV-Visible Spectrophotometer Now Available

The next generation of cuvette-free UV-visible spectrophotometers is now available for biotech and other life science laboratories.  More...
20 Oct 2015
Image: Micrograph showing brain cells with signs of Parkinson\'s disease (Photo courtesy of the University of Copenhagen).

Interferon-Beta Gene Therapy Reverses Parkinson's Disease Symptoms in Mouse Model

The lack of cytokine interferon-beta signaling in a mouse model caused formation of Lewy bodies in the animals' brains and triggered neurodegeneration similar to that seen in the brains of human Parkinson's disease patients.   More...
19 Oct 2015
Image: Scanning electron micrograph of Salmonella enterica (shown in red) (Photo courtesy of the [US] National Institute of Allergy and Infectious Diseases).

PCR-based Method Rapidly Detects Pathogens in the Environment

A newly developed PCR-based technique detects soil, air, and waterborne pathogens within 24 hours, which is three to four days faster than currently used culture-based methods.  More...
19 Oct 2015
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New Automated Extraction System Produces High Quality RNA-free DNA

A state-of-the-art precipitation-based system completely automates the DNA extraction process from primary tube sampling to final DNA elution into storage tubes.  More...
18 Oct 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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