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Pathology

Image: The Synapt G2 high definition mass spectrometer (HDMS) (Photo courtesy of Waters).

Metabolomics Analysis Applied to Investigate MPS

Inborn errors of metabolism (IEM) represent a group of about 500 rare diseases with an overall estimated incidence of 1/2,500. The diversity of involved metabolisms explains the difficulties in establishing their diagnosis. More...
17 Oct 2017
Image: Three-dimensional images showing the complex vascular system in ovarian cancer (left) and bladder cancer (right). Thick vessels are colored red, thin vessels colored blue (Photo courtesy of Nobuyuki Tanaka / Karolinska Institutet).

New 3D App Provides More Accurate Cancer Diagnosis

With further development of light-sheet microscopy based 3D imaging, researchers were able to examine tumor biopsy tissue in more detail than current 2D methods, resulting in improved intratumoral heterogeneity phenotyping and diagnosis of solid tumors. More...
16 Oct 2017
ELITech Group
Image: SelectMDx can be used to diagnose prostate cancer without doing a biopsy or an MRI scan (Photo courtesy of MDxHealth SA).

Liquid Biopsy Test Outperforms Prostate Cancer PCA3 Test

Of the nearly two million prostate biopsies performed each year, less than a third find cancer. Most of these men could have avoided a painful and invasive prostate biopsy procedure, with its associated complications and costs. More...
11 Oct 2017
Image: A new genetic test was highly sensitive at determining which pancreatic cysts are most likely to be associated with one of the most aggressive types of pancreatic cancer (Photo courtesy of Shutterstock).

Pre-Op Test Can Detect Some Pancreatic Cancers

A newly developed genetic test was highly sensitive at determining which pancreatic cysts are most likely to be associated with one of the most aggressive types of pancreatic cancer. The successful results are a critical step toward a precision medicine approach to detecting and treating pancreatic cancer. More...
09 Oct 2017
Image: Immunohistochemistry of estrogen-receptor-positive (ER (+)) breast cancer (Photo courtesy of Biocare Medical).

Genetic Test Discovered for Predicting Cancer Recurrence

Treatment failure, due to drug resistance, still remains a major obstacle for more effective anti-cancer therapy and personalized medicine. In estrogen-receptor-positive (ER (+)) breast cancer, approximately 40% to 50% of patients eventually develop tamoxifen-resistance. More...
04 Oct 2017
Image: The Hybrid Capture 2 modular system used for processing the digene HC2 HPV DNA Test of human papillomavirus infections (Photo courtesy of Qiagen).

HPV Testing Detects More Precancerous Lesions

Human papillomavirus (HPV) testing detects a higher number of precancerous cervical lesions than cytology-based Papanicolaou (Pap) smears in a female population including a proportion offered HPV vaccination according to a new study. More...
03 Oct 2017
Image: A photomicrograph showing Blastomyces organisms stained with Periodic Acid Schiff (PAS). Note the budding organism (arrow) and the underlying pyogranulomatous inflammatory reaction in the background (Photo courtesy of University of Alabama at Birmingham).

Immunocompromised Patients at Risk for Blastomycosis

Most invasive fungal infections in immunocompromised patients are caused by Zygomycetes, Aspergillus, and Candida, but literature about Blastomyces infection in immunocompromised patients has been sparse. More...
28 Sep 2017


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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