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Pathology

Image: A new study suggests that mutations in the gene CABLES1 may lead to Cushing syndrome (Photo courtesy of iStock).

Potential Genetic Cause of Cushing Syndrome Found

A recent study suggests that mutations in the gene Cdk5 And Abl Enzyme Substrate 1 (CABLES1) may lead to Cushing syndrome, a rare disorder in which the body overproduces the stress hormone cortisol. More...
22 Jun 2017
Image: A new study shows pre-op serum cholesterol level may have a significant impact with prognosis in renal cell carcinoma patients (Photo courtesy of Getty Images).

Pre-Op Cholesterol Level Predicts RCC Patients Survival

Renal cell carcinoma (RCC) is the most frequently diagnosed renal malignancy. The constant advances of modern imaging technologies and the percentage of incidentally detected renal tumors has constantly increased during the last couple of decades, and a good percentage of patients are still diagnosed with metastatic renal cell carcinoma (mRCC). More...
21 Jun 2017
Image: A histopathology of pancreatic adenocarcinoma, where the adenocarcinoma has wrapped around a nerve (center) (Photo courtesy of Johns Hopkins Medicine).

Pancreatic Cancer Potentially Diagnosed by ctDNA

Pancreatic cancer remains a devastating disease, with the diagnosis typically being made late. Circulating Tumor DNA (ctDNA) has shown promise as a screening test for various tumor types. More...
21 Jun 2017
Image: The Videssa Breast protein biomarker blood test for breast cancer evaluates 11 serum protein biomarkers and 33 tumor-associated autoantibodies (Photo courtesy of Provista Diagnostics).

Blood Test Offers Improved Breast Cancer Detection

Breast cancer is predicted to be the second leading cause of cancer deaths in the USA women. Approximately 232,000 cases of invasive breast cancer and 60,000 cases of ductal carcinoma in situ (DCIS) are diagnosed and 40,000 deaths occur annually. More...
16 Jun 2017
Image: Early research found that a genetic test could lead to a reduction in painful procedures and minimize the over-treatment of people at low risk for anal cancer (Photo courtesy of Queen Mary University of London).

Genetic Test Identifies Risk of Anal Cancer

Anal cancer is mostly caused by human papillomavirus (HPV), which is the same virus that causes cervical cancer. Diagnosis presents many challenges as full biopsies are painful, and taking a small sample of cells for cytology is problematic because lesions can be hidden. More...
14 Jun 2017
Image: New research shows changes in immune activity appear to signal a growing brain tumor up to five years before symptoms begin (Photo courtesy of iStock).

Immune System Changes Signal Early Brain Cancer

Glioma is a heterogeneous primary malignant brain tumor with a median survival time, for the most common adult subtype, glioblastoma, of only 14 months. Changes in immune activity appear to signal a growing brain tumor five years before symptoms arise. More...
14 Jun 2017
Image: A new study suggests using a new genomic-dequencing approach could help develop an assay that could detect cancer at early stages (Photo courtesy of Memorial Sloan Kettering Cancer Center).

Sequencing Approach to Detect Genomic Alterations

An early study evaluated a sophisticated new genomic-sequencing approach that analyzes cell-free DNA (cfDNA) in the blood of people with advanced cancer and will help development of a future assay that could potentially detect cancer in its earliest stages. More...
13 Jun 2017


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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