Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




New Test Measures Men's Fertility

By LabMedica International staff writers
Posted on 06 Nov 2018
Male fertility is a serious and growing concern globally. More...
Yet, the field of andrology faces critical gaps in diagnostic technologies and knowledge, affecting scientific advancement as well as clinical management by both reproductive endocrinologists and urologists.

Although effective at identifying descriptive parameters, traditional semen analysis fails to identify defects in sperm function. Put simply, it does not provide information about whether a man's sperm can fertilize an egg, and the probability of that man generating a pregnancy.

A team of scientists working with Cornell University (Ithaca, NY, USA) collected 208 semen samples from men having medical evaluations because of questions regarding their fertility. In addition to undergoing traditional semen analysis, the team tested the samples and assigned them prospectively into groups predicted to have low versus normal fertility. The samples were collected and processed using Cap‐Score Male Fertility Assay kits. Clinical outcomes were later reported for 91 of these men.

The team reported that men with normal Cap-Scores had a 2.78-fold higher chance of pregnancy than men with a low score, and a 4.23-fold higher success rate at achieving pregnancy in their first attempt at intrauterine insemination (IUI). In contrast, none of the elements of semen analysis, such as sperm swimming or concentration, had any relationship with male fertility. The team collected more Cap-Scores and clinical outcomes from a total of five fertility clinics and urology practices and using data from 124 men, the scientists generated a curve that translates a Cap-Score into the probability of generating a pregnancy.

Alexander J. Travis, VMD, PhD, an Associate Professor of Reproductive Biology and senior author of the study, said, “Out of all the tests commonly used to measure sperm, the Cap-Score is the only one that prospectively has been shown to indicate the probability of a man to generate a pregnancy. This new ability to diagnose a man's fertility status and ability to generate a pregnancy will let doctors counsel their patients toward a personalized journey to parenthood, using the approaches most appropriate for them.” The study was published on September 24, 2018, in the journal Molecular Reproduction and Development.

Related Links:
Cornell University


New
Gold Member
Latex Test
SLE-Latex Test
3-Part Differential Hematology Analyzer
Swelab Alfa Plus Sampler
New
Pan-Cancer Panel
TruSight Oncology 500
New
Celiac Disease Test
Anti-Gliadin IgG ELISA
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








DIASOURCE (A Biovendor Company)

Channels

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: A simple blood test could replace surgical biopsies for early detecion of heart transplant rejection (Photo courtesy of Shutterstock)

Blood Test Detects Organ Rejection in Heart Transplant Patients

Following a heart transplant, patients are required to undergo surgical biopsies so that physicians can assess the possibility of organ rejection. Rejection happens when the recipient’s immune system identifies... Read more

Pathology

view channel
These images illustrate how precision oncology Organ Chips recapitulate individual patients’ responses to chemotherapy (Photo courtesy of Wyss Institute at Harvard University)

Cancer Chip Accurately Predicts Patient-Specific Chemotherapy Response

Esophageal adenocarcinoma (EAC), one of the two primary types of esophageal cancer, ranks as the sixth leading cause of cancer-related deaths worldwide and currently lacks effective targeted therapies.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.