We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
LGC Clinical Diagnostics

Download Mobile App


24 Feb 2024 - 28 Feb 2024
05 Mar 2024 - 07 Mar 2024

PCR Screening and Typing, Toolset Expanded for Ebolavirus

By LabMedica International staff writers
Posted on 19 Aug 2014
Print article
Image: Colorized transmission electron micrograph (TEM) revealing some of the ultrastructural morphology of an Ebolavirus virion (Image courtesy of Cynthia Goldsmith and the US Centers for Disease Control and Prevention (USA; CDC ref# PHIL 1832), via Wikimedia Commons).
Image: Colorized transmission electron micrograph (TEM) revealing some of the ultrastructural morphology of an Ebolavirus virion (Image courtesy of Cynthia Goldsmith and the US Centers for Disease Control and Prevention (USA; CDC ref# PHIL 1832), via Wikimedia Commons).
A new real-time polymerase chain reaction (RT-PCR)-based assay for identification of the five Ebolavirus species and Marburgvirus has been added to the Ebolavirus diagnostics toolset.

altona Diagnostics, GmbH (Hamburg, Germany), focused on the development, approval, manufacturing, and marketing of molecular diagnostic test systems for the detection and quantification of pathogens, has added a real-time RT-PCR-based assay, the RealStar Filovirus type RT-PCR kit, for identification of the five known Ebolavirus species and of Marburgvirus to their product portfolio. In addition to other activities, altona Diagnostics was also among the first to make reliable diagnostic kits commercially available during outbreaks for severe acute respiratory syndrome (SARS), avian Flu, swine Flu, and enterohemorrhagic Escherichia coli (EHEC).

Together with their already existing RealStar Filovirus Screen RT-PCR kit for first-line analysis, which is currently being used in the epidemic epicenter in West-Africa by the European Mobile Laboratory, altona Diagnostics now offers a comprehensive assay family for the detection and characterization of filovirus RNA from human sample material. While the screen kit detects all five Ebolavirus species without differentiation, as well as Marburgvirus, the typing kit is meant to be used as a second-line assay for confirmation of positive results and to distinguish between the five Ebolavirus species as well as Marburgvirus. Both kits are compatible with various real-time PCR platforms.

“For us, in the current situation during this epidemic outbreak, it´s more relevant that we were able to come up with a ready-to-use first-line test kit for filoviruses , which is now used in Guinea and Nigeria to identify infected patients and which is stocked by several European reference institutions under their preparedness plans,” said Dr. Markus Hess, chief scientific officer of altona Diagnostics, “The characterization of a positive sample by using the RealStar Filovirus type RT-PCR kit for Ebola and Marburgvirus is more of epidemiological and scientific importance.”

The ready-to-use real-time PCR kits for screening and typing of filoviruses are available as research use only reagents, currently. The In-Vitro Diagnostic (IVD) CE-marked version of the RealStar Filovirus Screen RT-PCR Kit will be available in September 2014.

Related Links:

altona Diagnostics
RealStar Filovirus RT-PCR kits

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Specimen Collection & Transport
Complement 3 (C3) Test
GPP-100 C3 Kit
Gold Member
Turbidimetric Control
D-Dimer Turbidimetric Control

Print article


Clinical Chemistry

view channel
Image: Wireless Point-of-Care Testing for Hepatitis B Virus (Photo courtesy of Chulalongkorn University)

Wireless Hepatitis B Test Kit Completes Screening and Data Collection in One Step

Hepatitis B, a significant global health concern, is responsible for chronic liver diseases like cirrhosis and liver cancer which is one of the most common cancers worldwide. The challenge with hepatitis... Read more

Molecular Diagnostics

view channel
Image: Aptiva utilizes particle-based multi-analyte technology (PMAT) (Photo courtesy of Werfen)

Novel Immunoassays Enable Early Diagnosis of Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is an autoimmune disorder that typically presents as venous or arterial thrombosis and/or pregnancy loss. Diagnosing APS can be difficult as its symptoms often resemble... Read more


view channel
Image: The Gazelle Hb Variant Test (Photo courtesy of Hemex Health)

First Affordable and Rapid Test for Beta Thalassemia Demonstrates 99% Diagnostic Accuracy

Hemoglobin disorders rank as some of the most prevalent monogenic diseases globally. Among various hemoglobin disorders, beta thalassemia, a hereditary blood disorder, affects about 1.5% of the world's... Read more


view channel
Image: The photoacoustic spectral response sensing instrument is based on low-cost laser diodes (Photo courtesy of Khan et al., doi 10.1117/1.JBO.29.1.017002)

Compact Photoacoustic Sensing Instrument Enhances Biomedical Tissue Diagnosis

The pursuit of precise and efficient diagnostic methods is a top priority in the constantly evolving field of biomedical sciences. A promising development in this area is the photoacoustic (PA) technique.... Read more


view channel
Image: The companies will develop genetic testing systems based on capillary electrophoresis sequencers (Photo courtesy of 123RF)

Sysmex and Hitachi Collaborate on Development of New Genetic Testing Systems

Sysmex Corporation (Kobe, Japan) and Hitachi High-Tech Corporation (Tokyo, Japan) have entered into a collaboration for the development of genetic testing systems using capillary electrophoresis sequencers... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.